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» LymeNet Flash » Questions and Discussion » Medical Questions » Tafenoquine for Babesia?

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Author Topic: Tafenoquine for Babesia?
Charles12
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It's finally been approved by the FDA. Has anyone tried it?

There's a study on Pubmed from 1997 that concluded it was very effective against Babesia, and New York Medical College is doing a Babesia study with it.

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Keebler
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Hmmm. Nice to hear of some investigation for babesia.

I've not tried it though it does pique my interest. Just passing along some links for those wondering more.

The study link, itself, would be good to see, too. Hope they consider more than just one dose or even just three as babesia can be so hard to eradicate. I'm wary of short doses that are supposed to make the world right again. Still, starter links:


https://en.wikipedia.org/wiki/Tafenoquine

Tafenoquine

Excerpt:

. . . Like primaquine, tafenoquine causes hemolysis in people with G6PD deficiency.[2]

Indeed, the long half-life of tafenoquine suggests that particular care should be taken to ensure that individuals with severe G6PD deficiency do not receive the drug.

The dose of tafenoquine has not been firmly established, but for the treatment of Plasmodium vivax malaria, a dose of 800 mg over three days has been used.[5]

In 2018 United States Food and Drug Administration (FDA) approved single dose tafenoquine for the radical cure (prevention of relapse) of Plasmodium vivax malaria[6]. . . .


https://en.wikipedia.org/wiki/Glucose-6-phosphate_dehydrogenase_deficiency

Glucose-6-phosphate dehydrogenase deficiency

[paraphrased] . . . anyone who considers certain kinds of higher / IV Vitamin C therapy also needs to first rule out G6PD deficiency . . . .
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Keebler
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I thought I might look up the study but ran out of steam. Quite a few links pop up in this search at Google for:

Babesia, Tafenoquine "New York Medical College"
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Charles12
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It’s scheduled for release in 2021, if I remember correctly.

There’s a study on pub med, dating back to 1997, when it was still an experimental compound. It was the most effective substance tested.

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Keebler
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Thanks for bringing this to our attention.
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