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Wash Your Mouth out With Silver, to Treat Hard-To-Treat Mouth Infections? ScienceDaily (Mar. 8, 2012) � Yeasts which cause hard-to-treat mouth infections are killed using silver nanoparticles in the laboratory, scientists have found. These yeast infections, caused by Candida albicans and Candida glabrata target the young, old and immuno-compromised. Professor Mariana Henriques, University of Minho, and her colleagues hope to test silver nanoparticles in mouthwash and dentures as a potential preventative measure against these infections.
Professor Henriques and her team, who recently published their research in the Society for Applied Microbiology's journal Letters in Applied Microbiology, looked at the use of different sizes of silver nanoparticles to determine their anti-fungal properties against Candida albicans and Candida glabrata. These two yeasts cause infections including oral thrush and dental stomatitis, a painful infection affecting around seven out of ten denture wearers. Infections like these are particularly difficult to treat because the microorganisms involved form biofilms.
The scientists used artificial biofilms in conditions which mimic those of saliva as closely as possible. They then added different sizes and concentrations of silver nanoparticles and found that different sizes of nanoparticles were equally effective at killing the yeasts. Due to the diversity of the sizes of nanoparticles demonstrating anti-fungal properties the researchers hope this will enable the nanoparticles to be used in many different applications.
Some researchers have expressed concerns around the safety of nanoparticle use but the authors stress this research is at an early stage and extensive safety trials will be carried out before any product reaches the market.
Professor Henriques comments: With the emergence of Candida infections which are frequently resistant to the traditional antifungal therapies, there is an increasing need for alternative approaches. So, silver nanoparticles appear to be a new potential strategy to combat these infections. As the nanoparticles are relatively stable in liquid medium they could be developed into a mouthwash solution in the near future.
Moving forward Professor Henriques hopes to integrate silver nanoparticles into dentures which could prevent infections from taking hold.
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D. Al Groosh, G.B. Roudsari, D.R. Moles, D. Ready, J.H. Noar, J. Pratten. The prevalence of opportunistic pathogens associated with intraoral implants. Letters in Applied Microbiology, 2011; 52 (5): 501 DOI: 10.1111/j.1472-765X.2011.03031.x Need to cite this story in your essay, paper, or report? Use one of the following formats: APA
MLA Wiley-Blackwell (2012, March 8). Wash your mouth out with silver, to treat hard-to-treat mouth infections?. ScienceDaily. Retrieved March 10, 2012, from http://www.sciencedaily.com� /releases/2012/03/120308062553.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29 , to Treat Hard-To-Treat Mouth Infections? ScienceDaily (Mar. 8, 2012) � Yeasts which cause hard-to-treat mouth infections are killed using silver nanoparticles in the laboratory, scientists have found. These yeast infections, caused by Candida albicans and Candida glabrata target the young, old and immuno-compromised. Professor Mariana Henriques, University of Minho, and her colleagues hope to test silver nanoparticles in mouthwash and dentures as a potential preventative measure against these infections.
Professor Henriques and her team, who recently published their research in the Society for Applied Microbiology's journal Letters in Applied Microbiology, looked at the use of different sizes of silver nanoparticles to determine their anti-fungal properties against Candida albicans and Candida glabrata. These two yeasts cause infections including oral thrush and dental stomatitis, a painful infection affecting around seven out of ten denture wearers. Infections like these are particularly difficult to treat because the microorganisms involved form biofilms.
The scientists used artificial biofilms in conditions which mimic those of saliva as closely as possible. They then added different sizes and concentrations of silver nanoparticles and found that different sizes of nanoparticles were equally effective at killing the yeasts. Due to the diversity of the sizes of nanoparticles demonstrating anti-fungal properties the researchers hope this will enable the nanoparticles to be used in many different applications.
Some researchers have expressed concerns around the safety of nanoparticle use but the authors stress this research is at an early stage and extensive safety trials will be carried out before any product reaches the market.
Professor Henriques comments: With the emergence of Candida infections which are frequently resistant to the traditional antifungal therapies, there is an increasing need for alternative approaches. So, silver nanoparticles appear to be a new potential strategy to combat these infections. As the nanoparticles are relatively stable in liquid medium they could be developed into a mouthwash solution in the near future.
Moving forward Professor Henriques hopes to integrate silver nanoparticles into dentures which could prevent infections from taking hold.
Journal Reference:
D. Al Groosh, G.B. Roudsari, D.R. Moles, D. Ready, J.H. Noar, J. Pratten. The prevalence of opportunistic pathogens associated with intraoral implants. Letters in Applied Microbiology, 2011; 52 (5): 501 DOI: 10.1111/j.1472-765X.2011.03031.x Need to cite this story in your essay, paper, or report? Use one of the following formats: APA
MLA Wiley-Blackwell (2012, March 8). Wash your mouth out with silver, to treat hard-to-treat mouth infections?. ScienceDaily. Retrieved March 10, 2012, from http://www.sciencedaily.com� /releases/2012/03/120308062553.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine+%28ScienceDaily%3A+Health+%26+Medicine+News%29
Posts: 789 | From CT, | Registered: Jun 2006
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Marz
Frequent Contributor (1K+ posts)
Member # 3446
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Thanks for posting. Very interesting.
Wondering if colloidal silver used just to rinse mouth would work in the meantime until the mouthwash is developed?
Posts: 1297 | From USA | Registered: Dec 2002
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'Kete-tracker
Frequent Contributor (1K+ posts)
Member # 17189
posted
GOD... I was sucking down the colloidal silver solution per my LLND for aWhile there. (2 TBSP, 4 times a day) I HOPE there's no safety issue with "nanoparticle use"!
Interesting... They never say how strong this silver nano-particle solution IS that they're planning to have us swish around as a mouth wash.
It makes sense that it works, though, as external topical applications of silver products have been used quite extensively for Decades- i.e: to knock down bacterial & other infections of the skin- prior to the development of our "modern antibiotics", in the 1940s & '50s.
Re: "silver nanoparticles appear to be a new potential strategy" It's almost as if they're 'discovering' silver solutions all over again!
Posts: 1233 | From Dover, NH | Registered: Sep 2008
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Carol in PA
Frequent Contributor (5K+ posts)
Member # 5338
posted
Yes, they've used Silvadene Cream since the 70's at least, to apply to burns to prevent infection.
Something else you may be interested in to kill Candida is Gentian Violet solution.
It's not expensive, and is available at drugstores. I also found it at Amazon.com and most of the reviews were good.
However, Gentian Violet stains whatever it touches, so a silver solution would be alot less messy.
Editing to add, I've read some of the reviews for colloidal silver at iHerb and at Amazon, and people are using it for oral infections. Also almost every other infection you could think of, including in a nebulizer for bronchitis/pneumonia.
[ 03-10-2012, 04:12 AM: Message edited by: Carol in PA ]
Posts: 6947 | From Lancaster, PA | Registered: Feb 2004
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posted
"The candida yeast answer" has a protocol for candida. It's proprietor claims that it is extremely successful. Nanoparticle "biotic" silver is a main component of this program.
I've mentioned this program a few times here, but no one seems to know anything about it.
-------------------- -chaps �Listen to the bell, Borrelia. It tolls for thee!� Posts: 631 | From A little place called, "we'll see." | Registered: Apr 2010
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