Topic: Is far infrared impacting our antibodies to Bb?
Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Does photon therapy -> the release of electrons impact the antibodies to release ***trivalent minerals***?
"To improve counts per pixel and target-to-background ratios in single-photon imaging with antibodies,
Khaw et al. and Torchilin et al.
***modified antibodies with negatively charged chelating polymers. This process permitted the chelation of a large number of ***trivalent metallic radiolabel molecules*** per modified antibody molecule (26,27)"
Which simply means Bb breaksdown a Zn-protein (of ours) to use to make it's "zinc fingers".
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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hiker53
Frequent Contributor (5K+ posts)
Member # 6046
posted
Most of us may not know what a trivalent mineral is. Would you mind simplifying this.
-------------------- Hiker53
"God is light. In Him there is no darkness." 1John 1:5 Posts: 8879 | From Illinois | Registered: Aug 2004
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Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Many elements can have different electromagnetic "charges" like Cr++ (chromium 2) or Cr +++ (chromium 3) which is trivalent.
Tri = three and think of valence as the ***combining power***.
The botulism "anti-toxin" is trivalent.
I don't know what it is.
I suspect the anti-toxin to Bb maybe trivalent too.
O3?
Or
We know Bb has "zinc fingers" = likely zinc attached to cysteine and histidine.
Does its toxin remove zinc from one of our Zn-proteins in order to grab that zinc to make its zinc fingers?
But when Bb is "dead"...
If Bb's toxin cleaves (breaks apart)a zinc-protein (most toxins are zinc metalloproteinases), when Bb is destroyed and that toxin is released...
does the toxin continue to work -> way too much free Zn in the system?
What about histidine..it converts to histamine = major problem. Need for an anti-histamine, like Mg...
Mg citrate? Will it "disassociate" so we can use them "separately"?
Same /different?...how to we get trivalent citrate?
Downside of citrates?
"In particular, at equimolar concentrations of citrate and bile salt,
the trivalent citrate anion reduces the amount of bile salt binding by about 40%.
This suggests that the efficiency of cholestyramine-based bile salt sequestering drugs used in the reduction of hypercholesterolemia may be improved by
eliminating citric acid as an excipient and avoiding the use of fruit juices during ingestion."
(So if you are on Questran, no fruit juice?)
Any chemists here to help out?
BTW...the symptoms of too much zinc are awful.
[ 05-18-2009, 01:33 AM: Message edited by: Marnie ]
Posts: 9424 | From Sunshine State | Registered: Mar 2001
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