What Lyme patients need to know about general anesthesia
From American Association of Nurse Anesthetists:
An article in the American Association of Nurse Anesthetists (AANA)’s AANA Journal, “Lyme Disease and Anesthesia Considerations,” discusses possible effects of anesthesia on Lyme disease patients undergoing surgery.
Jan 8, 2018 -
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Keebler
Honored Contributor (25K+ posts)
Member # 12673
Anesthetic Considerations in Porphyrias [Jensen, Fiddler, Striepe]
Introduction
Porphyrias present special anesthetic challenges,
Excerpts
[Page 9] . . . B. Induction of anesthesia
Thiopental has accounted for the majority of drug-precipitated attacks(15, 35) but the multifactorial nature of porphyric crisis makes interpretation of isolated cases difficult. (18) Since dehydration, infection, fever, and endogonous steroid hormones themselves induce ALA synthetase, virtually any drug administered to a patient entering a porphyric crisis implicates that drug as a "trigger".(18)
Interestingly, even a known trigger may not induce an attack. (5, 44) . . .
. . . [top of page 10] Etomidate is porphyrinogenic in animal models.[46] . . .
[Reference: 46. Harrison GG, Moore MR, Meissner PN.
Porphyrinogenicity of etomidate and ketamine as continuous infusions. Br J Anaesth 1985; 57: 420-423.] -
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Keebler
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Member # 12673
Science Recorder | Jonathan Marker | Friday, December 13, 2013
According to a December 13 news release from Wolters Kluwer Health,
a recent study appearing in the December issue of Anesthesia & Analgesia (“Etomidate and General Anesthesia: The Butterfly Effect?”) identified
the widely-used anesthesia drug etomidate as a safety concern for patients receiving the drug during surgical procedures, because the drug may increase the risk of mortality or cardiovascular events. -
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