LymeNet Flash: Anesthesia, considerations with lyme, etc.

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»	LymeNet Flash » Questions and Discussion » Medical Questions » Anesthesia, considerations with lyme, etc.

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Topic: Anesthesia, considerations with lyme, etc.

Keebler
Honored Contributor (25K+ posts)
Member # 12673

posted

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From recent newsletter at LymeDisease.org

https://www.lymedisease.org/anthesia-lyme/?utm_source=Jan+13--CDC+Lyme+stats&utm_campaign=Jre-send+jan+6--NY+state+of+state&utm_medium=email

What Lyme patients need to know about general anesthesia

From American Association of Nurse Anesthetists:

An article in the American Association of Nurse Anesthetists (AANA)’s AANA Journal, “Lyme Disease and Anesthesia Considerations,” discusses possible effects of anesthesia on Lyme disease patients undergoing surgery.

Jan 8, 2018
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Posts: 48021 | From Tree House | Registered: Jul 2007 | IP: Logged |

Keebler
Honored Contributor (25K+ posts)
Member # 12673

posted

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http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/91842?#000000"

what type of M.D. tests for PORPHYRIA? Includes detail about: HPU / KPU . . . .

Some links here are expired yet you can find the detail by searching with article titles / authors.

http://anesthesiologyboards.com/pdfs/porphyria.pdf

22-page pdf:

Anesthetic Considerations in Porphyrias [Jensen, Fiddler, Striepe]

Introduction

Porphyrias present special anesthetic challenges,

Excerpts

[Page 9] . . . B. Induction of anesthesia

Thiopental has accounted for the majority of drug-precipitated attacks(15, 35) but the
multifactorial nature of porphyric crisis makes interpretation of isolated cases difficult. (18)
Since dehydration, infection, fever, and endogonous steroid hormones themselves induce ALA
synthetase, virtually any drug administered to a patient entering a porphyric crisis implicates
that drug as a "trigger".(18)

Interestingly, even a known trigger may not induce an attack. (5, 44) . . .

. . . [top of page 10] Etomidate is porphyrinogenic in animal models.[46] . . .

[Reference: 46. Harrison GG, Moore MR, Meissner PN.

Porphyrinogenicity of etomidate and ketamine as continuous infusions. Br J Anaesth 1985; 57: 420-423.]
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Posts: 48021 | From Tree House | Registered: Jul 2007 | IP: Logged |

Keebler
Honored Contributor (25K+ posts)
Member # 12673

posted

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etomidate

http://www.sciencerecorder.com/news/anesthesia-drug-etomidate-may-increase-risk-of-mortality-cardiovascular-events/

Science Recorder | Jonathan Marker | Friday, December 13, 2013

According to a December 13 news release from Wolters Kluwer Health,

a recent study appearing in the December issue of Anesthesia & Analgesia (“Etomidate and General Anesthesia: The Butterfly Effect?”) identified

the widely-used anesthesia drug etomidate as a safety concern for patients receiving the drug during surgical procedures, because the drug may increase the risk of mortality or cardiovascular events.
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Posts: 48021 | From Tree House | Registered: Jul 2007 | IP: Logged |

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