This is topic HBOT a reason why it works in forum Medical Questions at LymeNet Flash.

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Posted by Marnie (Member # 773) on :
Please try to follow:

The WFL hunts for insects to eat at night. While doing so, it is covered in Bb infected ticks which, when full, fall off and no longer contain Bb.

I order to see in dim light, the WFL has to have a lot of eye rods which produce rhodopsin = an enzyme and scramblase.

Dr. Robert Lane of Berkely said there is an enzyme in the WFL's blood that is capable of destroying Bb


Now...rhodopsin converts to transducin which clears cGMP = cyclin GMP (not c-di-cGMP)

Bb needs *cyclic* di GMP when in the tick.

The conversion of c-di-GMP to c-GMP involves:

Rpfg (a response regulator is needed for quorum sensing is involved in

*oxygen sensing. *

Rpfg has a HD-GYP domain and

hydrolyses cyclic di GMP to cGMP (which is degraded by transducin)

O2 sensors control c di GMP (esp. when O2 is limited.)

Repeating... O2 limited, cGMP is up and transducin clears cGMP,

closing the sodium channel.

***On the flip side, HBOT -> lowers cGMP (like transducin does).***

PMID: 786572

Bb has sodium antiporters (genes)...several.

cGMP dependent PKG (protein kinase gamma).

Lower cGMP and PKG is kaput.
Posted by Cass A (Member # 11134) on :
Dear Marnie,

What is a WFL?


Posted by Cass A (Member # 11134) on :
Dear Marnie,

What is a WFL?
Posted by sammy (Member # 13952) on :
Possibly White Foot Mouse
Posted by Keebler (Member # 12673) on :
WFL? White-footed (little?) mouse, a good guess.

Western Fence Lizard, perhaps, since there is a reference to its blood being able to destroy borrelia and I recall reading that years ago about this little critter which favors N. California.

[ 08-03-2019, 05:27 PM: Message edited by: Keebler ]

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