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» LymeNet Flash » Questions and Discussion » Medical Questions » Mepron, Biaxin or Zith, and Bactrim DS

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Author Topic: Mepron, Biaxin or Zith, and Bactrim DS
RZR
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If this combo is taken long enough...will it eradicate lyme, bart, and babs?

If so, why do LLMDs stop this and treat bart separately?

--------------------
Tick bite May 2009
Diagnosed June 2009

Posts: 2329 | From SouthEast | Registered: Jun 2009  |  IP: Logged | Report this post to a Moderator
nefferdun
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Dr. H uses this combo to treat all three infections, pusling flagyl or tindamax. It won't necessarily cure all three as you might need to change protocols and take stronger abx to wipe it all out.

Another protocol that is stronger on the bart is malaron, levaquin and doxy, pulsing flagyl or tindamax.

Not everyone can handle these drugs at once as they put a lot of stress on the kidneys and liver.

--------------------
old joke: idiopathic means the patient is pathological and the the doctor is an idiot

Posts: 4676 | From western Montana | Registered: Apr 2009  |  IP: Logged | Report this post to a Moderator
BoxerMom
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nefferdun is right. This protocol doesn't contain any of the first-line abx for Bart: Levaquin, Factive, Rifampin.

Most of us need to spend time on the best abx for each infection. That's why many LL docs treat for Lyme and one co-infection at a time. They can prescribe the most effective abx for each infection. Often, the best are the strongest, and cannot be combined.

You are still on a good combo.

--------------------
 - Must...find...BRAIN!!!

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SashaC
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Neffer,
How often do you pulse the flagyl/ tindamax? I've never tried that before.

I've taken flagyl every day for six weeks and it has caused alot of numbness and tingling in my hands and feet.

Maybe when I begin again I could ask my LLMD to pulse? Is that how the possible neuropathy from flagyl is usually avoided?

Also, are doxy and mino in the same family? I can't take doxy so my doc has me on mino.

Boxer, what ARE the "top of the line" meds for each infection? Malarone/ mepron for babs and Levaquin/ Rifampin for Bart is what I have understood. Is that right?

I often wondered why everything isn't treated at once. Is it because taking all at once is too hard on our organs, or because the different abx are contraindicated to take together?

Sorry for all the questions!

Thanks [Smile]

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RZR
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I just switched from the protocol I mentioned to Rifampin and Zith. I am terrified that babs might come roaring back.

So, I could take malarone or Mepron, Levaquin, and doxy? Levaquin is scary, but might think about it.

I will give it a couple of weeks and see if I start feeling better on Rifampin first.

I just never improved on Mepron, Zith, and Bactrim DS.

--------------------
Tick bite May 2009
Diagnosed June 2009

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BoxerMom
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Sasha - I agree with Mepron/Malarone for Babs.

Jennie - I just finished a round of Rifampin/Zith, and I found it very effective, but my Babs did come roaring back. Now I'm on Mepron/Zith/Mino.

How long did you take Mepron/Zith/Bactrim? It can take a long time to see improvement with Babs.

I have never seen Mepron and Levaquin prescribed together. Usually, to treat Babs while contolling Bart, Mepron is Rxed with Biaxin and/or Bactrim.

When Bart is dominant, Rifampin, Factive and Levaquin are the abx of choice.

--------------------
 - Must...find...BRAIN!!!

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nefferdun
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I have the book, The Treatment and Diagnosis of Human Babesiosis by Dr. S. I find this book helpful (although I do not like his book on bartonella). This book was published in 2006.

He gives treatment protocols from the three doctors. Most of it addresses treating babesia and not the co-infections. I have the book open now so I can copy the information more accurately for you.

Dr J protocol for lyme and babesia:

Mepron 750 mg (one teaspoon) twice a day with fatty meal
Zithromax 500 mg twice a day
Take both medications 5-7 days a week for 3-4 weeks followed by a week long break.
The week prior to the break patients take 500mg flagyl or tindamax twice a day for 3-5 consecutive days.

800 mg Ketek can replace Zithromax but should not be taken with zithro. Ketek is very active against lyme and is a macrolide that prevents Mepron resistance (like zithro).

In some patients he also prescribes artemisinin. A 150 lb person would build up to 700-900 mg twice a day with a one week break.

If this does not work he adds IV Clindamycin.
For resistant babesia he prescribes Lariam, Doxy, Zithro and Flagyl or Tindamax. When he is using more difficult to tolerate drugs he pulses the tindamax (flagyl) 3-5 days a week.

Dr. H's treatment for Bb, bartonella and babesia:

Bactrim DS twice a day
Macrolide - he prefers Zithromax 250mg twice day
Mepron 750 mg twice a day
100-300 mg artemisinin 3 times day (Allergy Research Group)
He does not use a cyst buster in this protocol.

Another protocol Dr. H uses is Malarone, Levaquin, Plaquenil and Doxycycline.

Dr. B's protocol:

Mepron 750 mg twice a day
Zithromax 600 mg per day
Artimisinin 100 mg three times a day

2nd option if first fails:
Malarone 3 pills twice a day
Bactrim DS twice a day
Flagyl ER (extended release) 750 twice a day
Macrolide - prefers zithromax

You can't take Rifampin with Mepron as they interact. Doxy lowers the serum levels of Mepron.

--------------------
old joke: idiopathic means the patient is pathological and the the doctor is an idiot

Posts: 4676 | From western Montana | Registered: Apr 2009  |  IP: Logged | Report this post to a Moderator
   

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