LymeNet Home LymeNet Home Page LymeNet Flash Discussion LymeNet Support Group Database LymeNet Literature Library LymeNet Legal Resources LymeNet Medical & Scientific Abstract Database LymeNet Newsletter Home Page LymeNet Recommended Books LymeNet Tick Pictures Search The LymeNet Site LymeNet Links LymeNet Frequently Asked Questions About The Lyme Disease Network LymeNet Menu

LymeNet on Facebook

LymeNet on Twitter




The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

LymeNet Flash Discussion
Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive


The Lyme Disease Network is a non-profit organization funded by individual donations.

LymeNet Flash Post New Topic  New Poll  Post A Reply
my profile | directory login | register | search | faq | forum home

  next oldest topic   next newest topic
» LymeNet Flash » Questions and Discussion » Medical Questions » Lyme Induced Lupus / Anti-DNA

 - UBBFriend: Email this page to someone!    
Author Topic: Lyme Induced Lupus / Anti-DNA
momintexas
Frequent Contributor (1K+ posts)
Member # 23391

Icon 5 posted      Profile for momintexas   Author's Homepage     Send New Private Message       Edit/Delete Post   Reply With Quote 
I believe a positive ANA can be fairly common in Lyme patients, but what about the Anti-DNA?

Does Lyme trigger the Anti-DNA as well?

Can Lyme induce Lupus?

[ 04-22-2011, 11:01 AM: Message edited by: momintexas ]

Posts: 1408 | From Tx | Registered: Nov 2009  |  IP: Logged | Report this post to a Moderator
Lymetoo
Moderator
Member # 743

Icon 1 posted      Profile for Lymetoo     Send New Private Message       Edit/Delete Post   Reply With Quote 
UP for those who know something about Anti-DNA!!

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
Lymetoo
Moderator
Member # 743

Icon 1 posted      Profile for Lymetoo     Send New Private Message       Edit/Delete Post   Reply With Quote 
No one has had this test??

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
Razzle
Frequent Contributor (1K+ posts)
Member # 30398

Icon 1 posted      Profile for Razzle     Send New Private Message       Edit/Delete Post   Reply With Quote 
I have had this test, but the ANA was high and the DS-DNA antibodies were negative.

I did have one positive Anti-Smith antibody show up once...

I do think Lyme can cause these antibodies, but don't know if that is the cause for everyone with elevated ANA's.

--------------------
-Razzle
Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs.

Posts: 4166 | From WA | Registered: Feb 2011  |  IP: Logged | Report this post to a Moderator
renny1985
LymeNet Contributor
Member # 25222

Icon 1 posted      Profile for renny1985     Send New Private Message       Edit/Delete Post   Reply With Quote 
My LLMD told me that Lyme can cause all sorts of autoimmune antibodies to spike up..I have the centromere AB which are indicative of scleroderma.. he says he doubts anything will come of this and its likely a result of Lyme...
Posts: 341 | From NY/FL | Registered: Apr 2010  |  IP: Logged | Report this post to a Moderator
ktkdommer
Frequent Contributor (1K+ posts)
Member # 29020

Icon 1 posted      Profile for ktkdommer     Send New Private Message       Edit/Delete Post   Reply With Quote 
I was diagnosed with lupus with only ANA at 1:640 and symptoms. The rest of my lupus panel was negative. That was 10 years ago at U of M. They were wrong. My son is ANA positive and Anti-Sm positive but nothing else on his lupus panel of labs.
I am interested to see if those labs return to normal further into treatment.
Lyme can mimic lupus. I should have been diagnosed atypical lupus if anything and should have been tested for Lyme.

--------------------
Things are never dull. After 3 fighting Lyme, 2 are in remission. Youngest is still sick, age 22. He has new diagnosed Chiari Malformation and Ehlers Danlos Syndrome.

Posts: 1366 | From Perrysburg, Ohio | Registered: Nov 2010  |  IP: Logged | Report this post to a Moderator
map1131
Frequent Contributor (5K+ posts)
Member # 2022

Icon 1 posted      Profile for map1131     Send New Private Message       Edit/Delete Post   Reply With Quote 
Today I was at the lovely yearly with gyn. When I went to give urine speciman and looked at myself in the mirror there was my bright red butterfly looking rash on my face.

I've had this numerous times in the last 7 yrs. Everytime I've seen my PCP that is my main doc and more than 70% lyme literate, I've not had the rash.

It comes and goes. I did notice this morning after I'd been up couple hours that my neck seemed to be rashed/whelp like? It was odd, but heck I'm used to weird stuff.

My PCP has probably tested me 6-8 times for Lupus ANA. I'm negative

Just looked up the test from '07 and it's LabCorp ANA w/reflex if positive
Antinuclear Antibodies Direct.

Would that be the same test?

Pam

--------------------
"Never, never, never, never, never give up" Winston Churchill

Posts: 6478 | From Louisville, Ky | Registered: Jan 2002  |  IP: Logged | Report this post to a Moderator
momintexas
Frequent Contributor (1K+ posts)
Member # 23391

Icon 1 posted      Profile for momintexas   Author's Homepage     Send New Private Message       Edit/Delete Post   Reply With Quote 
Thank you for your replies.

My ANA came back positive and so did my Anti-DNA (DS).

Pam - I'm not really sure if it's the same test that you had.

I'm just not sure what to think about my results and I'm waiting to hear more from the Dr.

I have been symptom free for a few months now except for a red butterfly rash that suddenly appeared on my chest a couple months ago.

It doesn't hurt or itch - it's just there. Heat from the shower and sunlight make it more pronounced.

I have read that a positive ANA test can mean a lot of things, but I'm having trouble finding any info on the Anti-DNA (DS).

Posts: 1408 | From Tx | Registered: Nov 2009  |  IP: Logged | Report this post to a Moderator
Razzle
Frequent Contributor (1K+ posts)
Member # 30398

Icon 1 posted      Profile for Razzle     Send New Private Message       Edit/Delete Post   Reply With Quote 
The Anti-DS-DNA is more specific to Lupus than just a generally elevated ANA... Some drug reactions apparently can also cause a positive DS-DNA antibody test. --from http://www.hopkins-arthritis.org/ask-the-expert/systemic-lupus-erythemato-022/anti-ds-dna-test-734.html

--------------------
-Razzle
Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs.

Posts: 4166 | From WA | Registered: Feb 2011  |  IP: Logged | Report this post to a Moderator
momintexas
Frequent Contributor (1K+ posts)
Member # 23391

Icon 1 posted      Profile for momintexas   Author's Homepage     Send New Private Message       Edit/Delete Post   Reply With Quote 
Thank you for the link!

I wish I could find what drugs that Dr is referring to.


How do people that have Lyme & Lupus deal with both??

Posts: 1408 | From Tx | Registered: Nov 2009  |  IP: Logged | Report this post to a Moderator
karenl
Frequent Contributor (1K+ posts)
Member # 17753

Icon 1 posted      Profile for karenl     Send New Private Message       Edit/Delete Post   Reply With Quote 
I had anti DNA, but now it is gone and I have only the 3,200 ANA.
Nobody can give me an explanation.

I think now they treat with low dose doxy.
There is a group of modern lupus docs and they treat with abx.
Pm me if you need more then I try to find my old files.

Posts: 1834 | From US | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
momintexas
Frequent Contributor (1K+ posts)
Member # 23391

Icon 1 posted      Profile for momintexas   Author's Homepage     Send New Private Message       Edit/Delete Post   Reply With Quote 
Up for any more info on Anti-DS-DNA testing in how it relates to Lyme or Lupus.
Posts: 1408 | From Tx | Registered: Nov 2009  |  IP: Logged | Report this post to a Moderator
   

Quick Reply
Message:

HTML is not enabled.
UBB Code� is enabled.

Instant Graemlins
   


Post New Topic  New Poll  Post A Reply Close Topic   Feature Topic   Move Topic   Delete Topic next oldest topic   next newest topic
 - Printer-friendly view of this topic
Hop To:


Contact Us | LymeNet home page | Privacy Statement

Powered by UBB.classic™ 6.7.3


The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA


| Flash Discussion | Support Groups | On-Line Library
Legal Resources | Medical Abstracts | Newsletter | Books
Pictures | Site Search | Links | Help/Questions
About LymeNet | Contact Us

© 1993-2020 The Lyme Disease Network of New Jersey, Inc.
All Rights Reserved.
Use of the LymeNet Site is subject to Terms and Conditions.