canbravelyme
Frequent Contributor (1K+ posts)
Member # 9785
posted
Hi all,
There is some literature linking Miralax (laxative: Polyethylene Glycol 3350) to mood swings.
Anyone experience any mood changes while taking Miralax?
Best,
-------------------- For medical advice related to Lyme disease, please see an ILADS physician. Posts: 1494 | From Getting there... | Registered: Aug 2006
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beaches
Frequent Contributor (1K+ posts)
Member # 38251
posted
Please provide links to the literature to which you are referring.
Posts: 1885 | From here | Registered: Jul 2012
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canbravelyme
Frequent Contributor (1K+ posts)
Member # 9785
posted
Hi Beaches,
Maybe I shouldn't have said literature, because it usually implies medical literature (which may be available, but I couldn't find on a Google search).
More accurately, there are some references. Here's a couple:
"The mainstream medical position has been that PEG is minimally absorbed from the intestine, and thus poses no systemic risk. But there are many anecdotal reports by parents of very serious adverse side effects of this medication, particularly neuropsychiatric symptoms, mood and anxiety symptoms, tics, self-stimulating repetitive behaviors, seizures, to name only a few. A Yahoo group dedicated to this concern has over 1700 members."
-------------------- For medical advice related to Lyme disease, please see an ILADS physician. Posts: 1494 | From Getting there... | Registered: Aug 2006
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posted
My Naturopath told me there are ingredients in Miralax that are used in anit-freeze. He said do not take this product!!!!
Posts: 620 | From Ks | Registered: Oct 2011
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beaches
Frequent Contributor (1K+ posts)
Member # 38251
posted
FWIW, my DD suffered through GI sx like no kid should EVER have to. She went through HELL and back over and over and over again for YEARS. She went through test after test after test. We tried every allopathic/naturopathic/holistic remedy under the sun.
We finally �stumbled� across an enlightened GI doc after YEARS of searching with NO expectation of any physician being able to relate to her in any way at all.
He wasn�t LL per se, this doc we came across, but he was very Lyme-aware and very respectful of my daughter and her significant medical history, him being from a medical center in an endemic area of the Midwest.
Guess what? His recommendation was that she do a full clean out with Miralax, followed by a nightly �maintenance dose� of Miralax. He explained the need for fluid intake when using Miralax.
Guess what again. The protocol he recommended is still working for her.
The only serious side effect we've seen from "this medication" aka Miralax is its ability to maintain bowel regularity.
You state: "The mainstream medical position has been that PEG is minimally absorbed from the intestine, and thus poses no systemic risk. But there are many anecdotal reports by parents of very serious adverse side effects of this medication, particularly neuropsychiatric symptoms, mood and anxiety symptoms, tics, self-stimulating repetitive behaviors, seizures, to name only a few. A Yahoo group dedicated to this concern has over 1700 members."
This has not been our experience at all. Hmm, those symptoms sound like they could be from Lyme/associated coinfections. Those parents might want to consider getting their kids evaluated for same.
posted
I've taken it for 8 years, because of pain meds, and don't have any psychiatric issues due to it. It is a bit scary looking at the chemicals in it. But, it's preferable to the effects of NOT taking it in some cases. It is also sold over the counter now, although I think it is still cheaper for me to use my rx.
-------------------- One day at a time Posts: 409 | From TX | Registered: Mar 2004
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posted
There is a whole support group on Yahoo on the negative aspects of taking Miralax
I suffer from IBS, ulcerative colitis and constipation... never had problems with the IBS
and colitis until I started abx... I too was told by my gastro to take Miralax. I do
"occasionally" but find high dose ascorbic (powder) Vit C and other options more natural
I am concerned about the Polyethylene Glycol 3350 content of Miralax
Posts: 396 | From EAPennsylvania | Registered: Dec 2007
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canbravelyme
Frequent Contributor (1K+ posts)
Member # 9785
posted
Hi Fourwinds,
I was reading the posts in the yahoo group this AM. I took some Miralax last night, and found myself thinking about things in a more easygoing way than usual (which is why I started researching Miralax and mood).
Who knows whether it was the Miralax, but I'm going to try to see whether I can control the hideously constipating effects of the Zofran naturally or with Colace...
-------------------- For medical advice related to Lyme disease, please see an ILADS physician. Posts: 1494 | From Getting there... | Registered: Aug 2006
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beaches
Frequent Contributor (1K+ posts)
Member # 38251
posted
canbravelyme,
We tried colace, vit c, mag, etc. etc. etc.
Nothing worked like the miralax!
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posted
Can Miralax be taken with meds and/or probiotics or is it another thing that has to be spaced?
Posts: 832 | From Somewhere | Registered: Nov 2010
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beaches
Frequent Contributor (1K+ posts)
Member # 38251
posted
terv, in my experience with DD the Miralax can be taken with meds and probiotics. She's been taking them all at the same time for quite awhile and it's worked for her.
Of course during times when she's on abx, the probiotics are taken separately. But she has taken abx with Miralax and there have been no issues at all.
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beaches
Frequent Contributor (1K+ posts)
Member # 38251
posted
fourwinds and canbravelyme,
I have to tell you both, I am surprised to even hear of this yahoo group. And, honestly, since the Miralax has worked so well for dd who had been so sick, I�m very hesitant to even explore this group! Lyme/cos has been so god-awful and enough already! I don�t need any more problems!
The sx that were mentioned previously and associated with use of Miralax�tics, neuropsych issues, etc. reek of tick-borne disease sx. DD�s sx have been greatly diminished with tx for same, along with the regular use of Miralax.
Canbravelyme, are you saying you felt a bit lighter after taking the Miralax? LOL Sorry, I just couldn�t resist!
Hope you feel better soon. I know how bad/painful it is.
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seekhelp
Frequent Contributor (5K+ posts)
Member # 15067
posted
My young daughter has been on Miralax every day for 3 years now. Her docs say it's completely safe.
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008
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posted
Miralax works differently than colace or some other laxatives. This is what I was told by my pain clinic. It stimulates the system to go, doesn't "soften" or change consistency. At least that's what they told me. The pain meds I take slow the system and the miralax is just to kick start it up.
-------------------- One day at a time Posts: 409 | From TX | Registered: Mar 2004
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posted
@beaches and @seekhelp ... yes I guess there are negatives to anything if we look hard enough, sigh.
I have concerns about pharmaceuticals and OTC "stuff" that has serious chemicals in it.
I am just one of those curious types that doesn't put anything in my mouth to swallow without looking it up, LOL.
There are so many "things" on the market that are dangerous that the FDA just closes their eyes to because it is profitable.
I view knowledge as empowerment with regard to my body. I've had too many doctors give me BAD advice. ("I" don't trust everything doctors tell us...;0
Ultimately, we each have to make our own decisions based on that knowledge..... Posts: 396 | From EAPennsylvania | Registered: Dec 2007
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Razzle
Frequent Contributor (1K+ posts)
Member # 30398
posted
I have had a bad experience with Miralax. It turned my guts to cement that was absolutely $##$@% to pass (manual extraction required). Worst stuff on the planet for me.
-------------------- -Razzle Lyme IgM IGeneX Pos. 18+++, 23-25+, 30++, 31+, 34++, 39 IND, 83-93 IND; IgG IGeneX Neg. 30+, 39 IND; Mayo/CDC Pos. IgM 23+, 39+; IgG Mayo/CDC Neg. band 41+; Bart. (clinical dx; Fry Labs neg. for all coinfections), sx >30 yrs. Posts: 4166 | From WA | Registered: Feb 2011
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