posted
I'm wondering if 200 micrograms of synthetic glucocorticoids is enough to compromise a lyme patient?
This is a specific question about triamcinolone, which has systemic activity of 70% through the nasal mucosa. (In constrast, fluticasone propionate only has 2% systemic bioavailability from intranasal application).
And what about topical betamethasone for dermatitis?
Posts: 200 | From Ohio | Registered: Apr 2016
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Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- Unless a life threatening emergency (and under the care of a LLMD with added protections),
avoid steroids, even topicals and nasal sprays. Even in the sinus cavity, steroids can make lyme in your whole body worse.
There are far better ways to treat nasal issues as well as dermatitis. Even in a skin lotion, it can make lyme in your entire body much worse. It has happened to others and there is not point in taking such a risk. These questions are addressed in articles here:
Topic: what do STEROIDS actually do to those with lyme? Risks, long term damage discussed. Links. -
Posts: 48021 | From Tree House | Registered: Jul 2007
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posted
I read that thread, and two things don't make sense:
1. Ashwagandha LOWERS cortisol. Absolutely terrible for someone with critically-low cortisol.
2. The thread says that low dose CORTEF let the adrenals rest? Actually, usage causes a downregulation of endogenous cortisol production, and can suppress the HPTA, as well as cause adrenal atrophy. How do either of those things "help the adrenals rest."???
I'm also interested in scientific literature that 200 micrograms of a synthetic glucocorticoid interfered with the immune response against bacteria.
Posts: 200 | From Ohio | Registered: Apr 2016
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Keebler
Honored Contributor (25K+ posts)
Member # 12673
. . . "Steroid Disaster" is a term coined by the pioneer of Lyme Treatment . . .
Corticosteroids are immune suppressants, the last thing a Lyme patient needs is to lower immunity. -
Posts: 48021 | From Tree House | Registered: Jul 2007
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Keebler
Honored Contributor (25K+ posts)
Member # 12673
posted
- To answer questions number
1. Ashwagandha lowers cortisol ONLY when the body needs that action. Search: ADAPTOGEN
Many lyme patients have very high spikes of cortisol at times and this can be damaging. Ashwagandha is an adaptogen. Detail as to what that means and to better understand all of it, see Wilson's book and other links in that set.
2. It's all about the PHYSIOLOGICAL REPLACEMENT DOSE and no more - see Wilson's book & also:
Safe Uses of Cortisol by William Jefferies
You can get Wilson's book - and maybe Jefferies, too - through any US library - the interlibrary loan system or through various web vendors. -
Posts: 48021 | From Tree House | Registered: Jul 2007
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TF
Frequent Contributor (5K+ posts)
Member # 14183
posted
You said:
"I'm also interested in scientific literature that 200 micrograms of a synthetic glucocorticoid interfered with the immune response against bacteria."
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96222 | From Texas | Registered: Feb 2001
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TF
Frequent Contributor (5K+ posts)
Member # 14183
posted
Nasacort (Discontinued in U.S.)
Posts: 9931 | From Maryland | Registered: Dec 2007
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desertwind
Frequent Contributor (1K+ posts)
Member # 25256
posted
I use it and no problems. My llmd, Dr. H., said not an issue. Now, the 4 months of Dexamethasone I was on....totally different story.
Posts: 1671 | From Tick Infested New Jersey | Registered: Apr 2010
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posted
It's not discontinued; its over the counter now in the USA, along with flonase, and even rhinocort.
Posts: 200 | From Ohio | Registered: Apr 2016
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randibear
Honored Contributor (10K+ posts)
Member # 11290
posted
my llmd said no steroidsin any way shape or form
-------------------- do not look back when the only course is forward Posts: 12262 | From texas | Registered: Mar 2007
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