LymeNet Home LymeNet Home Page LymeNet Flash Discussion LymeNet Support Group Database LymeNet Literature Library LymeNet Legal Resources LymeNet Medical & Scientific Abstract Database LymeNet Newsletter Home Page LymeNet Recommended Books LymeNet Tick Pictures Search The LymeNet Site LymeNet Links LymeNet Frequently Asked Questions About The Lyme Disease Network LymeNet Menu

LymeNet on Facebook

LymeNet on Twitter




The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

LymeNet Flash Discussion
Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive


The Lyme Disease Network is a non-profit organization funded by individual donations.

LymeNet Flash Post New Topic  New Poll  Post A Reply
my profile | directory login | register | search | faq | forum home

  next oldest topic   next newest topic
» LymeNet Flash » Questions and Discussion » Medical Questions » Quinoline (plaquenil) vs quinolone what is difference

 - UBBFriend: Email this page to someone!    
Author Topic: Quinoline (plaquenil) vs quinolone what is difference
TxLymie
LymeNet Contributor
Member # 20847

Icon 1 posted      Profile for TxLymie     Send New Private Message       Edit/Delete Post   Reply With Quote 
I just started plaquenil a week ago and feel terrible . I've never had tendinitis but I suppose that is what I now have in my neck shoulder area. My muscle/tendon is so tight it feels like a guitar strings and pops when massaged. Is plaquenil as dangerous as The FQ drugs? I am on a new abx regimen of plaquenil and clindamycin and feel horrible. I know it could also be a herx but feeling like this is not worth it.

I have been doing pretty well for several years… Back to 90% of my previous health most of the time. I began to experience a little more fatigue recently so went to my LL M.D. who recommended this treatment to hopefully eradicate lyme once and for all.

However now I'm worried that I could have caused permanent damage? Does plaquenil have the same dangers as Levaquin? thoughts?

--------------------
TxLymie
IgG-Negative
IgM - Postive bands 23 and 41

Other dx: 2000: Endometriosis 2009: Chronic EBV, Mycoplasma infection, HHV6, H.pylori

Posts: 297 | From Houston | Registered: Jun 2009  |  IP: Logged | Report this post to a Moderator
bluelyme
Frequent Contributor (1K+ posts)
Member # 47170

Icon 1 posted      Profile for bluelyme     Send New Private Message       Edit/Delete Post   Reply With Quote 
Hi tx , i dont believe plaq is in the floruidinated drugs ...ther is a list that tutu had ...it does have a extremly long half life like 6 wks and can effect eyes .it is immunosuppressive and may have anti babs cyst busting abilities but maybe try alinia or tinidazole ...?

--------------------
Blue

Posts: 1539 | From southwest | Registered: Dec 2015  |  IP: Logged | Report this post to a Moderator
Judie
Frequent Contributor (1K+ posts)
Member # 38323

Icon 1 posted      Profile for Judie     Send New Private Message       Edit/Delete Post   Reply With Quote 
Hydroxychloroquine (plaquenil) is a quinolone.

Fluoroquinolones are a combination of quinolones with fluoride.

The quinolone is one of the problem in fluoroquinolones.

I got refloxed on a plain, old quinolone drug. Ankle swelled up horribly.

Some people believe it's the fluoride that causes the quinolone part to go even deeper into the body.

Personally, I have no problem with fluoride. It's the quinolone part that does me in.

I got horrible problems from both fluoroquinolones (levaquin) and quinolones (primaquine).

Tinidazole also causes peripheral neurapathy and tendon problems. Be careful.

I wish I knew all this before I took any of these.

Posts: 2839 | From California | Registered: Jul 2012  |  IP: Logged | Report this post to a Moderator
TxLymie
LymeNet Contributor
Member # 20847

Icon 1 posted      Profile for TxLymie     Send New Private Message       Edit/Delete Post   Reply With Quote 
Thanks for the replies! I am still a bit confused though. Is there a difference in quinolones and quinolines. Spelling is almost the same.

And is there any way to tell if the quinolone (Plaq) is causing me issues...or is it a Herx? I already stopped taking plaq because I don't want to take my chances. I also had a lot of heart fluttering today...which is not a normal symptom for me. In fact, I feel so much worse now than when I went to the doc. I was actually not doing that bad but just wanted to knock out the Lyme once and for all but I'd rather just live with the "manageable symptoms" I had than feel like this....I have crazy fatigue, major joint and tendon pain, heart fluttering and can't sleep!

--------------------
TxLymie
IgG-Negative
IgM - Postive bands 23 and 41

Other dx: 2000: Endometriosis 2009: Chronic EBV, Mycoplasma infection, HHV6, H.pylori

Posts: 297 | From Houston | Registered: Jun 2009  |  IP: Logged | Report this post to a Moderator
Lymetoo
Moderator
Member # 743

Icon 1 posted      Profile for Lymetoo     Send New Private Message       Edit/Delete Post   Reply With Quote 
What quinolINE are you referring to?

http://medical-dictionary.thefreedictionary.com/quinoline

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
SickSam
LymeNet Contributor
Member # 45330

Icon 1 posted      Profile for SickSam     Send New Private Message       Edit/Delete Post   Reply With Quote 
I've researched this some more. QuinolINEs are not quinolones. It appears that quinolONEs are quinolINEs. I had it backwards the last time I posted about this. Quinolines are the superclass. Quinolones are the subclass.

See: http://wikidiff.com/quinolone/quinoline

So plaquenil isn't a quinolone, it's a quinoline. I'd venture to say that since they're basically derived from the same stuff though, they both could be harmful.

Also, plaquenil can rarely cause heart issues too.

[ 08-05-2016, 10:35 PM: Message edited by: SickSam ]

Posts: 748 | From Texas | Registered: Feb 2015  |  IP: Logged | Report this post to a Moderator
Lymetoo
Moderator
Member # 743

Icon 1 posted      Profile for Lymetoo     Send New Private Message       Edit/Delete Post   Reply With Quote 
NO wonder I can't tolerate either group. It contains a "benzene ring."

I'm pretty sure that is related to salicylates. No phenols or benzoates, etc.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96222 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
   

Quick Reply
Message:

HTML is not enabled.
UBB Code� is enabled.

Instant Graemlins
   


Post New Topic  New Poll  Post A Reply Close Topic   Feature Topic   Move Topic   Delete Topic next oldest topic   next newest topic
 - Printer-friendly view of this topic
Hop To:


Contact Us | LymeNet home page | Privacy Statement

Powered by UBB.classic™ 6.7.3


The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA


| Flash Discussion | Support Groups | On-Line Library
Legal Resources | Medical Abstracts | Newsletter | Books
Pictures | Site Search | Links | Help/Questions
About LymeNet | Contact Us

© 1993-2020 The Lyme Disease Network of New Jersey, Inc.
All Rights Reserved.
Use of the LymeNet Site is subject to Terms and Conditions.