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» LymeNet Flash » Questions and Discussion » Medical Questions » Biofilm inflammation - Rapid Relapsers - LymeMD Blog

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Author Topic: Biofilm inflammation - Rapid Relapsers - LymeMD Blog
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Very interesting:

Biofilm induced inflammation in mouse model and rapid relapsers

By LymeMD / Blog - December 15, 2018


. . . For me one of the clinical mysteries has been the rapidity with which clinical symptoms may relapse when antibiotics are stopped. . . .

. . . Lyme bacteria are pleomorphic and exhibit a great degree of phenotypic variability.

In layman’s words “they act like shape shifting aliens” which have widely invaded host bodies.

The Lyme bacterium is a long, thin, twisted bacteria, a spirochete of the genus Borrelia. There are various species and strains which may cause human disease.

Dr. Zhang describes 3-4 variations. The spirochetes may be aggregated in a rapidly growing biomass mathematically referred to as a logarithmic growth phase.

One might think this group with its very high numbers causes the most harm and one would be wrong.

a second group he calls microcolonies (aggregated biofilm like colonies).

This is a stationary group showing no active growth.

Individual spirochetes, free swimming are planktonic variants. In microbiology, planktonic bacteria are distinguished from organisms confined to biofilms.

Most of the planktonic bacteria are round forms. This is not something I have seen described with any other pathogenic bacteria. . . .

[full post at link above]

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