posted
I came across some very interesting material on Gallium Nitrate, used for cancer treatment and for horses with skin infections. It was found to be effective against syphilis in rabbits. It works by interfering with iron, manganese and other metal metabolism in bacteria. It's downside is that it can lead to anemia. The research article near the bottom here discusses this.
Trivalent gallium is also known to have antibiotic properties to iron-dependent bacteria, but it has not been tested in vitro against nanobacteria. Most recently, Harrington et al. [4] in 2006 reported that Gallium(III) kills Rhodococcus equi, an intracellular bacteria, which causes pneumonia in foals. The extensive review of Bernstein [5] showed that gallium was effective in treating experimental syphilis in rabbits, eliminated Trypanosoma evansi parasites from infected mice, killed Mycobacterium tuberculosis and Mycobacterium avium complex and was effective against malarial parasites. Bernstein suggested that it is likely that the activity stems from gallium's ability to enter microbes through their iron transport mechanisms, to disrupt their iron metabolism, and to interfere with protein synthesis. The ability of transferrin-bound gallium to enter infected cells through the transferrin receptor may be an advantage in treating some intracellular infections. Other bacterial infections are treatable with gallium nitrate. Eby [6] reported that a single topical application of a gallium nitrate solution was immediately effective in terminating pimples, acne, boils, folliculitis and carbuncles and other bacterial skin infections. Eby also reported that a 1% gallium nitrate isotonic saline ocular solution used each several hours for a day terminated overnight two treatment-resistant bacterial eye infections in humans. In 2007, Kaneko et al. [7] found that gallium inhibits Pseudomonas aeruginosa growth and biofilm formation and kills planktonic and biofilm bacteria in vitro. The antibacterial effects of gallium have not been systematically explored, but they appear broad, safe and useful.
Title: Inhibition of hemoglobin production by transferrin-gallium. Author: Chitambar, C R : Zivkovic, Z Citation: Blood. 1987 Jan; 69(1): 144-9
Recent clinical trials evaluating gallium nitrate as a chemotherapeutic agent have reported the development of microcytic hypochromic anemia in patients treated with this agent. Because gallium is known to bind avidly to transferrin, we examined the effect of transferrin-gallium (Tf-Ga) on hemoglobin production by Friend erythroleukemia cells in vitro. Cellular hemoglobin production, as assessed by benzidine staining, cellular hemoglobin content, and 59Fe incorporation into heme, was significantly decreased following exposure of cells to Tf-Ga. Tf-Ga led to an early decrease in cellular 59Fe incorporation even before changes in hemoglobin production were detected. A marked increase in cellular transferrin receptor expression occurred following exposure of cells to Tf-Ga. Tf-Ga inhibition of hemoglobin production could be reversed and hemoglobin production could be restored to normal by addition to the media of either transferrin-iron (Tf-Fe) or iron-pyridoxal isonicotinoyl hydrazone, a compound capable of supplying iron directly to reticulocytes for heme synthesis without transferrin as a mediator. These studies provide an explanation for the development of anemia in patients treated with gallium nitrate and suggest that gallium's mechanism of chemotherapeutic action includes inhibition of cellular iron incorporation.
Posts: 31 | From TX | Registered: Nov 2008
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Carol in PA
Frequent Contributor (5K+ posts)
Member # 5338
posted
I was curious, and looked to see if iHerb carried this.
It is present in trace mineral formulations, which get rave reviews.
Carol
Posts: 6947 | From Lancaster, PA | Registered: Feb 2004
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posted
Thanks for posting this. It's the only thing that claims to work against spirochetes, malaria-like parasites and mycoplasma, all-in-one.
I'd be interested in finding a good source.
Posts: 655 | From USA | Registered: Sep 2007
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emla999/Lyme
Frequent Contributor (1K+ posts)
Member # 12606
posted
You can purchase Gallium Nitrate directly from George Eby. Just click on the link down bellow and scroll down to near the very bottom of that page for ordering options.
****Before oral use, Gallium Nitrate must be diluted to a 1% solution. WARNING! THIS IS NOT OPTIONAL!
On page 1 on the link bellow George Eby tells how a woman helped relieve her osteoarthritis pain by taking 3 to 5 milliliters of the 14% concentrate mixed into about a half-gallon of water each day. She took gallium nitrate every other two weeks (two weeks on and two weeks off).
"Since the inhibitory concentration of Gallium is achievable in humans, and the relative potency of Gallium is greater than HU, additional studies of Gallium appear warranted."
CD57
Frequent Contributor (1K+ posts)
Member # 11749
posted
bringing this up. It was in a book of therapies written by Craig Bruner, which someone was talking about recently. I found this statement interesting. Bartonella and babesia are, I believe, iron dependent for survival. Wouldnt this be worth looking at?
Except no one seems to know how to take it.
I did more literature research and found that gallium was not only beneficial for bones and joints, but that it was strongly antibacterial to iron-dependent bacteria and mycobacterium, and that it was patented as a treatment for arthritis.
Posts: 3528 | From US | Registered: Apr 2007
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posted
I've been taking a homeopathic preparation of Galium in a product called Galium Heel.
Ive used this stuff on and off for years now. Ideally it should be combined with Lymphomyosot (according to the Heel company) to protect against viral infections and to boost of defensce mechinisms in cases of chronic disesaes.
Previously I usually did about 3 weeks of it every year or so... but since lyme I take it daily.
Posts: 803 | From USA | Registered: Oct 2013
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CD57
Frequent Contributor (1K+ posts)
Member # 11749
posted
great Carmen,and how is it?
Posts: 3528 | From US | Registered: Apr 2007
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posted
Its hared to say. Its one of those things that just builds the general strength of the immune system. Im not expecting a cure from it, only fortification.
I use to use Lymphomyosot when I had bad PMS stuff before I started BHRT. At that time I could really feel the difference sometimes in minutes. The galium heel works under the radar. I came across a video on a LLMD who uses the Heel remedies to support patients on a routine basis, but I cant seem to find it now. But I would say, after working with Heel remedies for over 10 years for different things that they should be seriously considered for detox and support.
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