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» LymeNet Flash » Questions and Discussion » Medical Questions » Manganese vs Magnesium

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Author Topic: Manganese vs Magnesium
canefan17
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What's the difference?

I'm trying to find good sources of manganese (ala Dr K's Pyloria tx)

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elley0531
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All I know is that Manganese is a completely different mineral than Magnesium and I'm pretty sure legumes are a good source. Not sure which ones though.
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massman
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Must be the same, they sound close enough [shake]
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canefan17
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That's why I was curious Dick
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seekhelp
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Massman, why don't you help answer questions too. [Smile]
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canefan17
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His way or the highway. That's the approach all the "know it alls" take.
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sutherngrl
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They are different, but I don't remember the difference. Guess I need to take some!
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canefan17
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Chuck!

What a website! Good stuff my man

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canefan17
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The name Chuck always makes me think of Charles Barkley. (haha random i know)
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massman
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Much more fun to ramble 'round here with goofy fun replies than try to actually help people !
[puke] [woohoo]

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elley0531
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Also Cane-I believe you mentioned that you eat a decent amount of quinoa-that is a very good source of manganese as well. I remembered that this morning when i was making it for breakfast.
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djf2005
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Massman-

If you are a DC I would have thought you would be a lot more compassionate, sharing, and understanding since most of the chiropractors I see are humble, unassuming, and extremely knowledgeable.

I guess I was wrong.

[puke]

--------------------
"Experience is not what happens to you; it is what you do with what happens to you."

[email protected]

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elley0531
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I love the hell out of my wellness chiro. He's like my cheerleader.
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ninjaphire
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I take a quarter of this pill (5mg).

http://www.iherb.com/Carlson-Labs-Chelated-Manganese-250-Tablets/13270?at=0

Works quite well for me.

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massman
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Nobody here likes to laugh, do they ?


How could one be compassionate with those who already know everything ?

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elley0531
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who claims to know everything? This thread started as a question...but anyway.

Greens are also a great source-just looked this up because it made me curious. Mustard Greens, Kale, Romaine lettuce-so pile up the greens!

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kitty9309
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quote:
Originally posted by massman:
Much more fun to ramble 'round here with goofy fun replies than try to actually help people !
[puke] [woohoo]

But, you did not help answer this question, only had a rude comment.
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kitty9309
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quote:
Originally posted by massman:
Must be the same, they sound close enough [shake]

Where is the answer here?
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canefan17
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elley,

Thanks. Ya I do eat quite a bit of quinoa.

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ping
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cane - My LLMD (now retired) told me that soy products usually contain good sources of manganese, esp. soy sauce. Also said that too much would make Lyme sx's very active.

--------------------
ping
"We are more than containers for Lyme"

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MDW005
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is mangosteen a derivative of mangos?

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God's promises mean you always have something wonderful to look forward to.

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MDW005
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never mind just read Ping's post

--------------------
God's promises mean you always have something wonderful to look forward to.

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sutherngrl
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Ping, very interesting! I had a severe reaction to soy sauce at a chinese restaurant.

One of my lyme symptoms is feeling like my throat is closing up. It was during a period where it had been a little worse than normal and we went to eat chinese and I put soy sauce on my rice.

About 20 minutes after finishing my meal, it felt like my throat was completely closed up. I almost went to ER it was so bad.

Anyway haven't been back to that restaurant again since then. Didn't know if it was the soy sauce or all the MSG they use in their food.

I also had an increase in other lyme symptoms but thought it was from the trauma of the whole ordeal of the throat closing up.

Now I wonder!

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ping
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sutherngrl: I think it was to you I sent this LLMD's patient manual. He talks about manganese reaction(s) in there. Too bad for me as well because I loved soy sauce. Now the problem isn't manganese for me but hypertension.

--------------------
ping
"We are more than containers for Lyme"

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djf2005
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quote:
Originally posted by massman:
Nobody here likes to laugh, do they ?


How could one be compassionate with those who already know everything ?

Hmmm. Good Point.

Those like you perhaps??

Plenty here like to laugh. Most people do not laugh at condescending, sarcastic, and utterly useless comments.

--------------------
"Experience is not what happens to you; it is what you do with what happens to you."

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seibertneurolyme
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Not sure it is a good idea to supplement this mineral in excess. Lyme uses managanese rather than iron to multiply.

Bea Seibert

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seibertneurolyme
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Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3449-54. Epub 2009 Feb 13.

A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi.

Ouyang Z, He M, Oman T, Yang XF, Norgard MV.

Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Borrelia burgdorferi (Bb), the causative agent of Lyme disease, is transmitted to mammalian hosts through an arthropod (tick) vector.

To establish infection, Bb must acquire essential nutrients, including transition metals, from its mammalian and tick hosts. Thus far, no metal transporter has been identified in Bb.

Here, we report the identification of the first metal transporter, BmtA (BB0219), in Bb. BmtA-deficient mutants of virulent Bb were readily generated, and the mutants grew slightly slower than wild-type Bb in vitro.

However, BmtA mutants were sensitive to the chelating actions of EDTA, suggesting a role for BmtA in metal utilization. Intracellular accumulation of manganese (Mn) was substantially diminished in the bmtA mutant, indicating that BmtA was operative in Mn uptake.

Given that BmtA lacks homology to any known Mn transporter, we postulate that BmtA is part of a novel mechanism for Mn acquisition by a bacterial pathogen. BmtA also was essential to the infectious life cycle of Bb in ticks and mammals, thereby qualifying BmtA as a new borrelial virulence factor.

In addition, the bmtA mutant was sensitive to treatment with t-butyl hydroperoxide, implying that BmtA, and thus Mn, is important to Bb for detoxifying reactive oxygen species, including those potentially liberated by immune effector cells during the innate immune response.

Our discovery of the first molecule involved in metal transport in Bb provides a foundation for further elucidating metal homeostasis in this important human pathogen, which may lead to new strategies for thwarting Lyme disease.

PMID: 19218460 [PubMed - indexed for MEDLINE]

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Pinelady
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So you think we should not take manganese as Bb uses it cellular?

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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bv
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Somewhere, maybe here, maybe elsewhere, I read that BB metabolizes manganese. I showed the article to my LLMD---he said stay away from it. It nourishes BB.

Magnesium, on the other hand, is a totally differnt chemical than manganese. Magneisum is supposed to help with neuro symptoms, especially muscle twitches & burning skin & other peripheral nerve symptoms.

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gwb
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quote:
Originally posted by massman:
How could one be compassionate with those who already know everything ?

I don't know everything. That's why I pm you with questions sometimes because I think you can give some good advice and input.

By the way, think you'll have some time to answer my recent questions I sent you in a pm? Look forward to it. [Smile]

Gary

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seibertneurolyme
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pinelady,

I guess managanese is kind of like B12 -- it is a necessary nutrient and some people may need supplements since lyme obviously uses up the nutrient.

Just picked up a new issue of the monthly health newsletter, Developing Healthy Habits, at my local health food store. Manganese was the feature nutrient. This is what Dr. Linda Page says about manganese.

Quote -- A mineral that nourishes brain and nerve centers to eliminate fatigue, nerves and low back pain, and aids in sugar and fat metabolism. SOD (superoxide dismutase), a powerful free radical quenching enzyme, is solely dependent on manganese for its immune enhancing activity. Manganese boosts calcium in nourishing bones, and reduces epileptic seizures.

Deficiencies result in poor hair and nail growth (white spots on nails), hearing loss, blood pressure imbalances, impotence, latent diabetes, and poor muscle coordination.

Tranquilizer drugs deplete manganese. Manganese supplements protect nerves from adverse effects of tranquilizers.

Food sources: blueberries, ginger, rice, eggs, green vegetables, legumes, nuts and bananas. -- End Quote

Seizures, hearing loss, blood pressure imbalances, poor muscle coordination .... Sounds a lot like lyme symptoms.

Oh wow, talk about a smart bug. The abstract I posted above says that Bb uses the manganese to block free radicals generated by a person's immune system -- it is diverting the SOD for its own purposes is what it sounds like to me.

There are 2 kinds of SOD -- I forget what the other one is. looked it up -- the 2nd kind of SOD contains copper and zinc.

Bea Seibert

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seibertneurolyme
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Neuropediatrics. 2005 Dec;36(6):386-8.

Autoantibodies to human manganese superoxide dismutase (MnSOD) in children with facial palsy due to neuroborreliosis.

Eiffert H, Karsten A, Ritter K, Ohlenbusch A, Schlott T, Laskawi R, Christen HJ.

Department of Medical Microbiology, University Hospital, G�ttingen, Germany.

AIM: Acute peripheral facial palsy due to neuroborreliosis is associated with a distal neuritis. In patients with Lyme disease the activity of antioxidant enzymes is decreased.

With respect to the pathogenesis of neuroborreliosis, sera of children with acute peripheral facial palsy were investigated for autoantibodies against human manganese superoxide dismutase (MnSOD), which were suspected of raising the oxidative injury of infected tissues.

METHODS: Sera of 20 children with acute peripheral palsy with neuroborreliosis, sera of 20 children with facial palsy without reference to Lyme disease and sera of 14 blood donors were tested for antibodies against human MnSOD using an ELISA.

RESULTS: The concentrations of IgM autoantibodies to MnSOD of the children with neuroborreliosis were significantly increased, compared with the two control groups.

CONCLUSIONS: We propose that the antibodies detected block the protective effects of MnSOD resulting in an increased oxidative inflammation.

PMID: 16429379 [PubMed - indexed for MEDLINE]

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Pinelady
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Thats interesting about the Manganese boosting Calcium. The dern things build biofilm out of calcium.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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sutherngrl
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So we shouldn't take manganese??? It is in multi vitamins.
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n.northernlights
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article on manganese transporter http://www.pnas.org/content/106/9/3449.full
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