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» LymeNet Flash » Questions and Discussion » Medical Questions » Biaxin vs Zith

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Author Topic: Biaxin vs Zith
bcb1200
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So, I've been on Biaxin pretty much since June.

Looks like I'm going to be adding Bactrim DS to the regimen in a few weeks.

I see most take it with Zith, but will Biaxin do as good of a job?

I'd. Like to avoid Zith if possible. Too many ear issues already.

--------------------
Bite date ?
2/10 symptoms began
5/10 dx'd, after 3 months numerous test and doctors

IgM Igenex +/CDC +
+ 23/25, 30, 31, 34, 41, 83/93

Currently on:

Currently at around 80% +/- most days.

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joalo
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Up.

--------------------
Sick since January 1985. Misdiagnosed for 20 years. Tested CDC positive October 2005. Treating since April 2006.

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onbam
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Think biaxin has the same ear issues, but not sure...
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jkmom
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I like Biaxin better than zith for my muscle twitching.

My daughter is taking Biaxin and Bactrim.

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BackinStOlaf
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From what I've read, Biaxin is a better drug orally than Zith. Wish I knew this before as I took Zith for months.

Also, PLEASE lookout for any strange side effects from Bactrim, like a headache, rash or fever!! very important!

--------------------
First Symptom 9/09
Multiple docs, negative Labcorp test
LLMD: 1/10
Positive Igenex/CDC test
Treatment 2/10
2/10-8/10 Amox, ceftin, zith, flagyl
Currently: Bicillin, Minocycline, still dealing with severe breathing issues

 -

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17hens
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My daughter was on Bactrim and Biaxin for a few months. Worked fine.

--------------------
"My flesh and my heart may fail, but God is the strength of my heart and my portion forever." Psalms 73:26

bit 4/09, diagnosed 1/10

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sammy
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My doctor prescribed Biaxin instead of Zithromax.
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lymednva
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I've been on both, at different times and had good results when used in the right protocols. Toward the end of my year of zith (all my insurance would cover) my white count went down, so my LLMD wanted me off anyway.

--------------------
Lymednva

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'Kete-tracker
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Quote:
"From what I've read, Biaxin is a better drug orally than Zith."

Depends on what you're fighting, 'Back'!
Most lower respiratory bacterial infections are pummeled by azithromycin.
On the other hand, "Zith"- as you folks like to refer to it here- is not particularily effective against borrelia Burgdefori BY ITSELF. (See the various abx reviewed in "Dr. B's guidelines".)

However, when it is combined with something like cefuroxime axetil (Ceftin), the combo is more efficacious than 'Ceftin' alone, & consequently is a very popular combo used by many LLMDs.

Getting back to the original inquiry made by 'bcb', it's common to combine clarithromycin (Biaxin) with an agent that raises the inter-cellular pH levels up (to be less acidic), such as hydroxychloroquine (Plaquenil) or Amantadine HCl (Symmetrel).

This alkaline "buffering" of the tissues is thought to help the effectiveness of the 'Biaxin' in combating Lyme bacteria within the cells.
(I'm surprised no-one had pointed this out yet)

However, as with any drug, there Are risks. For example, extended use (months) of Plaquenil at higher dosing levels MAY have a detrimental effect on vision (even permanent damage) and should be discussed with your doctor. An initial "base-line" vision check is recommended to detect any problems early on.

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bcb1200
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I'm on Amantadine with my Biaxin and have been for months for the reasons you state.

I asked about Biaxin vs Zith because I always see people mention Mepron/Zith or Bactrim DS / Zith combos. Yet I'd prefer to stay on Biaxin because a)I know I do well on it and b)I don't need any more tinnitus and I hear Zith can cause it.

I'll be adding Bactrim DS in a few weeks and probably Rifabutin and was wondering if Biaxin used in combination with these two is as effective as Zith.

Also, since I've been on Biaxin for 4 months, is it time to switch it up?

--------------------
Bite date ?
2/10 symptoms began
5/10 dx'd, after 3 months numerous test and doctors

IgM Igenex +/CDC +
+ 23/25, 30, 31, 34, 41, 83/93

Currently on:

Currently at around 80% +/- most days.

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DebraKelly
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my doctor put me on Biaxin instead of zith only because my medical wouldn't pay for zith. Although, Biaxin worked great with Bactrim, then with malarone.

It was not a pleasant experience, with the ears, nausea, etc. but it did work very well.

The best was adding accupuncture. It made me get through when it got really bad. I highly recommend it.

Good luck!

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Remember to Smile
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Beware! Both can cause permanent ear damage. Beware!

I was on zith briefly, then stopped it due to bad tinnitus. Hadn't had tinnitus issues at all until 2010.

Switched to Biaxin, and tinnitus remained at same "zith level" for several months.

Next, increased Mepron dosing and felt very good! Hooray! Long-standing pains upon taking deep breaths were GONE for the very first time after decades with that babesiosis symptom. Wow! I actually experienced why others suggest one take a deep breath. It can be quite pleasant!

Then, tinnitus got worse. I decided I didn't want to risk having tinnitus like this or even worse for the rest of my life. Consulted with my LLMD and stopped Biaxin.

Ultra-loud tinnitus episodes ceased, but base-level ringing is unending & worse overall. Have been advised this may be permanent, or may clear with Borrelia treatment.

And, yup, pains all over are back every time I take a deep breath or exert myself.

Gotta smile anyway, for the endorphins...

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Sophie1234
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May I ask, are we talking about these combos in treating Babesia specifically? Or Lyme, Babesia, etc?

The reason I ask is that I am currently trying to focus on Babesia; am on Malarone, Artemisinin and have just added Zithromax. It seems to be giving me tummy issues, and I do really well with Biaxin.

Can I substitute the Biaxin for the Zith, and stay with the Malarone and Art? Thanks!

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lululymemom
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yes, you can substitute Zith with Biaxin.. Any macrolide abx will work with Malarone. Many can't tolerate Zith and use Biaxin. This combo is usually used to treat Babesia.

--------------------
IGM 41 IND, 83-93+ IGG 31 IND,34 IND, 41++, 58+, 83-93 IND

31 Epitope test neg.

Bartonella henselae 1:100

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Sophie1234, you're wise to tackle babesosis. It may be the key to many LD patients who haven't achieved long-term remission.

Malarone, zith, and artemisinin are all helpful in battling Babs.

Mepron is a parallel for Malarone. For Mepron to be effective, patients must take it with zith, Biaxin, or a similar Rx. Also, the dose must be ingested w/ at least 25 to 26 grams of total dietary fat to be effective because Mepron is "barely water soluble."

When I eat the appropriate amount of fat, I do fine. If the meal is a little short, a handful of sunflower seeds, almonds, or walnuts can bring up the fat content in a healthy way. Having quacamole as a dinner appetizer is good, too.

If I feel a little chemical nausea after Breakfast or Dinner dosing, a slice of Ezekial bread or some brown rice crackers curtails the problem swiftly.

Malarone may be similar, but I don't know.

Artemisinin should be taken on an empty stomach, at least 2 hours away from Rx abx.

It is my understanding that zith offers more benefits to LD patients than Biaxin, so if you're tolerating it, keep going!
Smile

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