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» LymeNet Flash » Questions and Discussion » Medical Questions » Why is band 41 included on the WB if a positive result is not significant?

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Author Topic: Why is band 41 included on the WB if a positive result is not significant?
Tennessee1
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I had an IGenex Western Blot and tested IgG band 39 indeterminate and band 41++.

My LLMD (who is really a general internist who has taken a few courses on Lyme disease) said my results don't indicate Lyme. He said that a positive on band 41 means nothing and band 39 indeterminate means nothing.

My question is why is band 41 included in Lyme testing if it means nothing? Not only is band 41 included, it's a double-starred band which I understood makes it one of the more important bands in identifying Lyme disease.

What do you think? Is a positive on band 41 significant or not?

Posts: 18 | From Tennessee | Registered: Jun 2011  |  IP: Logged | Report this post to a Moderator
lou
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Have you read the explanation of the WB? It might give you the answer you are looking for:

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=042077;p=0

Other good info contained also in the quick links sticky at the top of the forum page.

Posts: 8430 | From Not available | Registered: Oct 2000  |  IP: Logged | Report this post to a Moderator
Lymetoo
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There are other non-specific bands that are also tested for. I suspect that it gives the doctor a better picture of what is going on.

I do believe 41 is important! It is often the first to show up. Band 39 is "the most specific borrelia band of all."

--

VITAL INFORMATION ON BAND 41!!!!

From a seasoned poster: (NOT Lymetoo)

The number of people exposed is in the millions. The reason you can't get treated is they have decided that only early disease merits diagnosis and treatment. The bacterium itself is the most bizarre human bacterial pathogen known, and is poorly understood.

They don't know how many people are carrying a permanent relapsing brain infection. you can't get diagnosis or treatment because they have to pretend it doesn't exist and use labels like 'post lyme' and 'CFS' etc. for those who manifest illness.

Look at what Steere did in his 1992 study which is the foundation for the CDC serodiagnostic standard. He and others often look back on this and refer to a 'normal' control, but in fact the control was taken from sick people...MS sufferers, CFS sufferers, in sum, conditions which could have been caused or complicated by late Bb infection. Moreover, he threw in 25 syphilitic patients which constituted 20% of the control. However, syphilis itself has an annual US incidence of 3 per 100,000.

This statistical chicanery, which fudged the result at 41 kDa on Bb blot by many multiples, is significant, because syph serum will cross react at 41 kDa to Bb western blots. It allowed them to 'swift boat' the importance of the reaction to 41 kDa, which is the earliest and most consistent human ab response to Bb infection, being present in all stages as opposed to the rest of the proteins which are variably expressed according to stage, tissue type, even temperature.

Flagellin {41kDa} is necessary for Bb to survive under all conditions, and is constantly expressed, including in late CNS infection. Yet they chose to swift-boat this response.


Why? It's for political and economic reasons. telling the truth about diagnosis and treatment results in mass panic and probable economic collapse/political revolution. it's likely a bioweapon. North American disease is different from European disease...lack of CSF antibodies, for instance.

A much larger range of serum resistance to host species in wild{allows Bb to infect a much wider range of species, important in disease spread and maintenance in wild}. The CDC has found that Bb 31 goes intracellular in CNS cells.

Telling the truth threatens the careers and livelihoods of the very individuals who control this issue and who have actively lied and deceived and otherwise operated a scientific propaganda campaign for the past 15+ years, profitting from the campaign as they went.

Lyme disease, which in the US also perhaps includes other pathogens notably a bioweaponized bartonella, threatens the entire establishment. If late disease was rare, we'd be able to get treatment. Unfortunately, the EIS/CDC,DOD totally screwed this up and tried to make money off of the disease, making profitability their first priority as opposed to protecting the health of americans.

Think about this...Allen Steere wouldn't listen to Polly Murray in early 90's when she reported a big incidence of neuropsychiatric disease in lyme. She had to call Fallon. Now, Fallon has overwhelming evidence of a serious disabling relapsing brain condition which is not easily treated.

Global hypoperfusion on spect/pet ain't normal folks. Don't you think the CDC etc. should be breaking their balls trying to figure it out? Instead, we see nothing at all, only continued attempts to deny illness and obstruct treatment.

Obviously, they know what is going on, and have determined that the best course is to do nothing, to cover up, knowing that in doing so, they are condemning large numbers of people to perpetual diagnostic and treatment hell.

Think about it. It's a horrific scandal and I'm not sure how much longer these *******s can keep control of it.

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 95889 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
t9im
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Lymetoo:

The swift boat veterans told the truth. I equate these honorable veterans with courage and conviction.

Are you implying Steere is correct in what he did?

--------------------
Tim

Posts: 1111 | From Glastonbury, CT | Registered: Apr 2010  |  IP: Logged | Report this post to a Moderator
CountryMouse
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quote:
Originally posted by t9im:
Lymetoo:

The swift boat veterans told the truth. I equate these honorable veterans with courage and conviction.

Are you implying Steere is correct in what he did?

Um, Lymetoo didn't write that post, but repeated it. It says so at the top of the post.

--------------------
Country Mouse

6/2011 IgX:
IGG: 31 IND, 41+++, 45+, 58+
IGM: 31+, 39 IND, 41 IND, 83-93 IND
Band 31 confirmed to be Lyme epitope by Igenex 7/2011

8/2011 IgX: POSITIVE
IGG: 31+, 34 IND, 39 IND, 41++, 45+, 58+
IGM: 31+, 34 IND, 39 IND, 41++, 83-93+

Posts: 169 | From Western Mass | Registered: May 2011  |  IP: Logged | Report this post to a Moderator
Lymetoo
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quote:
Originally posted by t9im:
Lymetoo:

The swift boat veterans told the truth. I equate these honorable veterans with courage and conviction. -- {ABSOLUTELY!!}--

Are you implying Steere is correct in what he did?

--As Country Mouse said, I did not write it.--

QUOTE: "Look at what Steere did in his 1992 study which is the foundation for the CDC serodiagnostic standard.**** He and others often look back on this and refer to a 'normal' control, but in fact the control was taken from sick people..."

**** Which we all know is flawed.****



--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 95889 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
Beth22
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swift boating has become a term in and of itself that no one probably even connects anymore to the original meaning.
and it is pejorative, because those accusations were all discredited.
but i just read that a post was deleted cause it was political, so i say no more.

Posts: 236 | From Zionsville IN | Registered: Jan 2011  |  IP: Logged | Report this post to a Moderator
   

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