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» LymeNet Flash » Questions and Discussion » Medical Questions » Yale study re: immune response to spirochete proteins

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Author Topic: Yale study re: immune response to spirochete proteins
MamaBear11
LymeNet Contributor
Member # 25116

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This was in my local paper today:

"Immune response may be cause of long-term Lyme effects"

Non-infectious proteins of the species of bacteria that cause

Lyme disease can remain in the body for a long time after

antibiotic therapy, and are capable of causing an inflammatory

immune reaction that could contribute to the development of

antibiotic-resistant arthritis, Yale researchers have found.

Although Lyme disease is quickly responsive to antibiotics, up

to 25 percent of patients experience prolonged

musculoskeletal symptoms that linger after treatment, and

some develop an arthritis that no longer responds to

antibiotics, according to the study published in the online

Journal of Clinical Investigation.


Lyme patients who develop persistent, painful joint

inflammation after treatment may be suffering from an immune

response to these proteins rather than a lingering bacterial

infection, the researchers said.


"This study provides the first direct evidence that spirochete

proteins can remain long after the bacterium is gone, and in

places where people can experience symptoms after

treatment for Lyme disease," said lead author Dr. Linda K.

Bockenstedt, professor of medicine and rheumatology at Yale

School of Medicine.

--------------------
Untreated Lyme for 25+ years.
Two kids, too much pain & fatigue, no hope of ever being able to treat.

Posts: 310 | From Northeast | Registered: Mar 2010  |  IP: Logged | Report this post to a Moderator
Keebler
Honored Contributor (25K+ posts)
Member # 12673

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-
So many excellent lyme researchers do not agree with that report.

Sad to see the newspapers print that without question. And, if your paper did, all papers might.

And no one will know that Yale is dedicated to discounting chronic lyme. And that campaign will costs lives.
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Posts: 48021 | From Tree House | Registered: Jul 2007  |  IP: Logged | Report this post to a Moderator
poppy
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So Wormser has his little amber theory and Yale has their little protein theory. Seems to be an infinite number of ways to deny that chronic infection occurs.

I always look to see who the authors are before I read one of these things, because certain people are predictable as to whether truth ever comes out of their mouths.

And this arthitis resistant to antibiotics stuff...they mean resistant to a short course, ignoring all the people who are improved with antibiotics and decline without them. Imbeciles or liars, take your choice.

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MichaelTampa
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Sounds like just the standard hogwosh theories of the losers/liars.
Posts: 1927 | From se usa | Registered: Mar 2010  |  IP: Logged | Report this post to a Moderator
WPinVA
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Do doctors have to check their common sense at the door when they enter med school?! I shouldn't say that because SOME doctors are wonderful but jeesh, here, we have remaining spirochetes and remaining symptoms and these doctors still call it "non-infectious."
Posts: 1737 | From Virginia | Registered: Aug 2011  |  IP: Logged | Report this post to a Moderator
Lymetoo
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I thought that was from this link...

http://www.medpagetoday.com/InfectiousDisease/GeneralInfectiousDisease/33337

but I believe it is different .. this one mentions MGH and Steere

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 95725 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
   

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