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» LymeNet Flash » Questions and Discussion » Medical Questions » C-diff, Vanco & probiotics

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Author Topic: C-diff, Vanco & probiotics
JCarlhelp
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Getting mixed messages whether to do probiotics at same time or whether this weakens vanco as it kills the probiotics. Any thoughts?
Posts: 366 | From Kalamazoo, Michigan | Registered: Jun 2008  |  IP: Logged | Report this post to a Moderator
Marnie
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Everything I've read says if C. Diff...need probiotics too.

Maybe a synergy...a good thing.

http://www.nutraingredients.com/Research/Probiotics-show-potential-to-stop-C.-difficile-Study

"When MDRp inhibitors are present, however, the activity of berberine against gram-positive bacteria, like C. difficile, increases by 60-fold.

Hence this combination of MDR efflux inhibitors and berberine results in a powerful antimicrobial agent capable of eradicating C. difficile."

http://www.northeastern.edu/news/stories/2009/01/lewisnihcdifficile.html


MDRp = multi drug resistant pump. In other words, the pathogens are capable of "spitting out" the drugs so to prevent that we give a healing medicine and another one that prevents the pathogen from spitting it out called a MDR efflux inhibitor.

"Several trials are currently being conducted to develop drugs that can be co-administered with antibiotics to act as inhibitors for the efflux-mediated extrusion of antibiotics.

None of the efflux inhibitors tested is yet in clinical use.

However, some of them are used to determine the efflux prevalence in clinical isolates.

Its shown that Verapamil can inhibit P-glycoprotein mediated efflux which can increase oral absorption of some compounds.

Some chemicals found in plants have potential as reflex pump inhibitors.

Chemicals such as Capsanthin and capsorubin, carotenoids isolated from paprika; the flavonoids, rotenone, chrysin, phloretin and sakuranetin."

Wikipedia.

This is why in medical schools of old, there were adjacent gardens full of plants and herbs. That is where many of our medicines to cure sick people originally came FROM.

If not cured...this is a very unique approach (donation from a spouse) - no joke:

http://www.smart-publications.com/blog/a-poop-transplant-fecal-matters-no-sh

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canefan17
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I just ordered this product...
(supposed to be the best for C Diff)
I've talked to people who said it saved their life.

http://www.forresthealth.com/supernatant-synbiotic-formula.html

Also Dr H makes his patients go on Florastar (sachorromyces boullardii)
2 caps per day.

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Maryland Mom
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Definitely do probiotics with vanco, but try to space them apart by taking the probiotics either 1-2 hours before the vanco, or 4-5 hours after.
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chastain
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I had C diff. It put me in intensive care and nearly killed me. I took Bio K plus, culturelle and vanco all at the same time. I believe it was the simultaneous combo of the probiotics and the vanco that saved my life. Jess.
Posts: 651 | From ct | Registered: Sep 2011  |  IP: Logged | Report this post to a Moderator
canefan17
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What is Vanco?
Posts: 5394 | From Houston, Tx | Registered: Aug 2009  |  IP: Logged | Report this post to a Moderator
Marnie
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No flora in gut/extrmemely reduced =

weight loss (pretty extreme and can happen fairly quickly),

passing undigested food,

sometimes nausea too,

extreme depression (neurotransmitters plummet).

The above comes from personal experience - son, likely food poisoning = extreme foul diarrhea followed by appendectomy one week later with abx after = no beneficial bacteria left (stool spec. sent to lab = only a few E. Coli and some yeast remaining). Two months later...20# weight loss and the other symptoms (extreme depression).

LOADING doses of probiotics (Essential Formulas - whole package in one weeks' time) turned him around, but it took nearly 2 years for complete "recovery"...rebalancing.

We need a healthy gut - lots of the "good guys" - to help us absorb nutrients which are used to make OUR proteins, our neurotransmitters, etc.

There is a catch...we need adequate *sodium* in our gut to help us absorb glucose and amino acids from our foods.

http://www.livestrong.com/article/286681-hypoglycemia-vegan-diet/

Bb likes the sodium (and chloride) channels open. He uses NaCL for motility and the amino acids to make "his" RNA/DNA and cell walls and cell membranes.

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