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» LymeNet Flash » Questions and Discussion » Medical Questions » Thyroid hormones cause muscle atrophy!

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Author Topic: Thyroid hormones cause muscle atrophy!
Indica440
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My thyroid hormones cause slow but steady muscle atrophy. I dont get it yet. Maybe its because of adrenal fatigue? I had my body temp going up when i took hydrocortisone (10-10-5 or just one dose of 30-35) but my muscles woud get weak and sluggish after i took the hydrocorti - which means im low in testosterone.

Has anyone here had these problems?
Its so confusing!!!

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poppy
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How did you decide that thyroid hormones were doing this? Very unlikely, I would say.
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Indica440
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because i notice an increase of muscle loss and fat loss on hormones.... i need the hormones because i cant think without them.

why you think its very unlikely?!

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poppy
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Unlikely because I have never heard of such a thing. Thyroid affects metabolism. Do a google search of hyperthyroid and hypothyroid and see what too much or too litle will do.

If muscle wasting is happening at the same time that you are taking thyroid meds, then it is coincidental and unrelated.

What does your doctor say about your thyroid dose?

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Indica440
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doctors dont have a clue. usually they say its a bit too low. but if i go higher the wasting gets worse and worse. i dont get it...
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Lymetoo
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Get your testosterone checked and supplement if needed. That will help your muscle loss.

--------------------
--Lymetutu--
Opinions, not medical advice!

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lpkayak
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i have been on both cortef and armour for over 20 yrs...in theat time i have exercises intermittently

sometimes i gain muscle and fitness other times i atrophy and have muscle problems

but i dont think it is realted to the meds

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Lyme? Its complicated. Educate yourself.

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canefan17
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Rhodiola has helped me increase and build muscle. Also it's a big time help for adrenals.

I use Gaia Herbs Adrenal Health.

Go slow with it - it can be too stimulating if you don't find right dose.

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Pocono Lyme
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I agree with Lymetoo to get your testosterone level checked.

From below link. hmm

Interestingly, thyroid hormones can cause muscle wasting due to both excess and deficiency by yet-unknown mechanisms.


http://ajpcell.physiology.org/content/290/2/C650.full

--------------------
2 Corinthians 12:9-11


9 But he said to me, �My grace is sufficient for you, for my power is made perfect in weakness.� Therefore I will boast all the more gladly about my weaknesses, so that Christ�s power may rest on me.

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Indica440
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i dont understand that arcticle at all. i only know most thyroid patients dont have that.... thats my question. why do i have it?

need to check testosterone, right!

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MichaelTampa
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Hydrocortisone is an adrenal hormone, not a thyroid hormone. I did read an article recently suggesting that hydrocortisone and testosterone were similar enough that they do compete for usage in the body, and was stating that as a mechanism for hydrocortisone causing muscle wasting. I'm not giving any opinion that the article was correct or not, but suggesting that might be what you would want to look into.
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CherylSue
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Have you been eating enough protein and are you supplementing with enough magnesium?
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Indica440
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yes.... more than enough. i never had this before my illness with lyme and co.

i also had it BEFORE hydrocirtosone.
its scary as hell!

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nonna05
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I used to takev a natural thyroid ,before I got sick//50mg. Nature I could tell mentally in 3 day's if I stopped .

Then they started only making a combo.that didn't help

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Sammi
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I have been treating Hashimoto's Thyroiditis for years. Despite frequent exercising, at one time I loss muscle tone. I had all of my hormone levels tested (estrogen, progesterone, estradiol, testosterone, cortisol) and they were all low.

I believe the low testosterone was the culprit. After treating the deficiencies, my muscle tone returned to normal. I agree with the others to have it tested. I recommend having all levels checked through saliva testing. Aeron Lab and ZRT Lab are both good. I actually had some of it covered when I used Aeron.

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TerryK
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I guess the key is getting the correct amount.

Annu Rev Nutr. 1997;17:457-85.

Hormonal regulation of human muscle protein metabolism.

Rooyackers OE, Nair KS.

Endocrinology Division, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.

Abstract
A continuous turnover of protein (synthesis and breakdown) maintains the functional integrity and quality of skeletal muscle. Hormones are important regulators of this remodeling process.

Anabolic hormones stimulate human muscle growth mainly by increasing protein synthesis (growth hormone, insulin-like growth factors, and testosterone) or by decreasing protein breakdown (insulin).

Unlike in growing animals, insulin's main anabolic effect on muscle protein in adult humans is an inhibition of protein breakdown. Protein synthesis is stimulated only in the presence of a high amino acid supply. A combination of the stress hormones (glucagon, glucocorticoids, and catecholamines) cause muscle catabolism, but the effects of the individual hormones on human muscle and their mechanisms of action remain to be clearly defined.

Although thyroid hormone is essential during growth, both an excess and a deficiency cause muscle wasting by yet unknown mechanisms.

A greater understanding of the regulation of human muscle protein metabolism is essential to elucidate mechanisms of muscle wasting.

PMID: 9240936 [PubMed - indexed for MEDLINE]

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Indica440
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I noticed that my girldfriend who is hypothyroid since a 1 year has started developing the SAME muscle athropy issues as i. It seems like its more hormone related (!) and not lyme/candida whatever. Its really the same patternm skinning out the muscles on the arms and legs and losing overall body fat... bascially the whole body is getting thinner and losing fat everywhere (!)

i think its not just testosterone which is out of balance but also other hormones. for example hydrocortisone helps me, but not enough yet and it makes my muscle weakness worse so this means i have low testosterone.

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Sammi
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I agree it is likely hormone related. I think it is possible if one (or more) hormone is off it may affect the others.

I recommend having saliva testing done to check all levels.

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Indica440
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Is this low testosterone? My muscles are all so soft and flabby and they just shrink and shrink [Frown]

Workouts help to some point but they begin to shrink again within days.

I really lose my mind with this crap...

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OtterJ
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I am also taking hormone replacement. I am also taking fruitcake, chex party mix (homemade) and a cookie called "haystacks" that my grandma used to make. This is called being a pig. The family party is next weekend and my willpower is not holding up. I am flabby and fat. Oh well. Not feeling like a treadmill, well, okay maybe for a few minutes. Can I pour ChexMix into the cupholder, or is that bad form? [shake] [Roll Eyes] [Big Grin]
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Indica440
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did anyone here in this thread have muscle wasting because of low testosterone?!
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Sammi
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I believe mine was caused from low testosterone.
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Sammi
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I believe mine was caused from low testosterone.
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