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» LymeNet Flash » Questions and Discussion » Medical Questions » zithromax

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Author Topic: zithromax
Holly Beth
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I heard on the news that Zithromax is dangerous to the heart. I'm suppose to start taking it with Doxy.

I'm afraid to do so but I feel I should because I want to continue with my doc tx recommendations. Has anyone else heard about this?

Anyone here taken Zith for a long period of time?

Posts: 84 | From way over the rainbow | Registered: Oct 2012  |  IP: Logged | Report this post to a Moderator
Holly Beth
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Also, I did talk to my Dr ad he still wants me to start it. Just was wondering what other people thought!?
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droid1226
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I take 1000 mg daily IV no problems

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http://www.youtube.com/user/droid1226/videos?view=0&flow=grid

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kidsgotlyme
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My DD was on it for a long period of time. She had to stop it due to ringing in her ears. I have never heard of heart issues. I would just watch for any new or worsening symptoms when starting.

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symptoms since 1993 that I can remember. 9/2018 diagnosed with Borellia, Babesia Duncani, and Bartonella Hensalae thru DNA Connections.

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Holly Beth
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This was all over the local news last week.Here is the link:


http://www.foxnews.com/health/2013/03/12/fda-warns-zithromax-can-cause-fatal-irregular-heart-rhythm/

Zith, I believe also treats Bart. That's another reason why I'm afraid to take it. I have tried Levaquin and Rifampin for a very short time.

I had to quit because my Bart symptoms got so bad with both of them when I herx:( Unfortunately I get throat swelling with Bart.

I couldn't handle it getting worse. Being on Doxy alone my throat has improved. It's not 100% but definately better.

My doc said I have to address this Bart issue because it will eventually get bad again. I know I have to but scared of the throat issues:(

So frustrated!

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munchin
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I've been on zith for 6 months no problems
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Lymetoo
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If you are young and have no obvious heart issues, I would give it a whirl. Just be aware and on the lookout.

--just my humble opinion--

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--Lymetutu--
Opinions, not medical advice!

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faithful777
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The warning was about people with low blood pressure. If you are okay on that, you should be alright with zith.

--------------------
Faithful

Just sharing my experience, I am not a doctor.

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tdtid
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I too was on several rounds of it and like a previous poster, I did it by way of IV as well.

The only complication I had was after IV and taking it orally again, I started feeling like my ears were clogged.

The doctor took me off and it did Biaxin interest. The ear issues cleared right up. I had never heard anything about the heart being involved.

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"To Dream The Impossible Dream" Man of La Mancha

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happydaychick
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I've been taking Zithromax (1000 mg daily) for 3 months now. It is causing ringing in my ears, which is driving me absolutely nuts, so I am hopefully going off it next week. But, otherwise, I've had no problems and it is a million times easier on the gut than doxy.

Good luck!

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Summer3
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This is just my opinion, and of course you should always check with your doctor if you have concerns, but I personally, would not hesitate in taking zithromax. I think for my situation, the damage that Lyme is doing to my body is far greater than the slight risk of zithromax to do harm.

I looked into the study briefly again this morning and I read it right when it came out last May. According to the NEJM table that was published with the study, there were 85.2 cardiac deaths per million courses of zithromax. That works out to be a risk factor of 0.000008% as opposed to 0.000003% for amoxicillin. Yes that is a higher risk, but the overall risk is pretty small.

The warning about prolonged qt has been on most handouts for zithromax for a very long time. All of a sudden the FDA is bringing attention to it. Zith is prescribed very often in z-packs and insurance often resists covering it as long-term tablets. In my opinion, insurance companies have a lot to do with warnings that come out on meds. If you notice, the study pushes for using amoxicillin which is notoriously a very inexpensive medication as compared to zith. Biaxin (the main macrolide substitute) has a similar risk for cardiac incident. So do the fluoroquinolones.

It's a personal choice and each individual needs to look at the risk factors for their situation. I'm completely comfortable taking most oral antibiotics, but others are not. I think that as long as I had a doctor I trust who monitors side effects carefully, I wouldn't hesitate in taking it.

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http://www.lymepie.blogspot.com

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Keebler
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-
QT issues (that can come from Zith) can be managed, primarily with magnesium - and some other key support methods.

MAGNESIUM is so important to have with ANY lyme treatment, not just to help regulate heart rhythm but for so many other reasons.

Lyme is so toxic that it poses far greater risk than any medicine to treat it. Still, meds can stress the body. Therefore, support methods are absolutely vital to help. Starting with liver support.

I think that, perhaps, the QT issues that can come from Zith (and other drugs) could be because of die-off, the herxheimer reaction, that is not accounted for by most doctors. That increases the toxicity load in the body but, without support, it can affect the heart. Support seems to help the medicines work more safely. And, just to be sure this message gets across, repeating - and a visual cue to help us remember:

MAGNESIUM MUST BE ON BOARD

LIVER SUPPORT MUST BE ON BOARD


http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=3;t=030792;p=0

LIVER & KIDNEY SUPPORT & and several HERXHEIMER support links, too.


See the QT (heart rhythm) detail here and talk with your doctor if you have any concerns:


http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=077325;p=0#000000

CARDIAC INFO & SUPPORT

Includes:

Dr. B's SAFE EXERCISE and PT Rehab guidelines,

EXERCISE INTOLERANCE is (partially) explained in the article: "when exercise doesn't work out" (and what we can do about that)

ADRENAL, CARDIAC, MITOCHONDRIA & MYELIN SUPPORT - that all helps movement better work for us

Styles discussed: Pilates; Qi Gong; Tai Chi; Yoga; water; strolling; etc.
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Keebler
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-
happydaychick,

You report tinnitus from zith. Sadly, that is a side effect that can go beyond just annoying.

And, sadly, lyme is also so very toxic that it can cause all kinds of ear damage, too. So, it has to be addressed - somehow.

There is no perfect treatment option, sadly. And any all ways are complex and can take a long time. There is just no way around that.

For all my cautions that "support helps increase Rx safety" it may not always prevent the kinds of issues around the ears.

Zith is ototoxic and it has even caused hearing loss or tinnitus that may reach unstoppable levels (and can be quite serious).

But, again, lyme is one of the most toxic infections known to man so it can't be ignored. But we can support our bodies to better tolerate treatment.

LIVER SUPPORT is absolutely vital to go before, during and long after ANY drug that is ototoxic (and so many are).

More detail here:

http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=065801

Topic: TINNITUS: Ringing Between The Ears; Vestibular, Balance, Hearing with compiled links - including HYPERACUSIS
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[ 03-28-2013, 02:51 PM: Message edited by: Keebler ]

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Keebler
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-
Coinfections are important to sort out so that the most effective treatment protocol can be outlined.

Parasites should also be considered -- treating parasites first can help just about any lyme protocol work better (and, hopefully, then faster - but it's still along haul).

See

http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/122300?

Parasite Warrior thread

- I've not read all of this but do know that more and more LLMDs are finally coming back to what Willy Burgdorfer found when he first identifyed Borrelia b - that parasites traveling with it may be a major coinfection. Others seem to be finding that if parasites are ignored, lyme is just so much harder to address.


When Rx are just not possible or don't seem to be the ticket, consider:


http://flash.lymenet.org/scripts/ultimatebb.cgi?ubb=get_topic;f=1;t=117755;p=0

Topic: RIFE Machine - Reference LINKS

LL Naturopathic links here, too.
-

[ 03-28-2013, 02:49 PM: Message edited by: Keebler ]

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gmb
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I was on oral Zith two years straight with many combinations of other oral and IV's.

Don't worry

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Holly Beth
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Thanks everyone, I'm on my second day of zith and doxy together. Still alive:)
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norahh
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I just wanted to add to this thread and say that I, too experience ringing in my ears, strange ear popping and pressure when I began the IV Zithromax. After 4 months it got so bad, I could hardly sleep. I changed to ceftriacone. After a few weeks these symptoms cleared up. Occasionally a mild version of the ringing reappears.
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Holly Beth
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I actually had ringing in my ears off and on for a couple yrs before I was diagnosed. Went to ENT and got all the hearing/ear tests done and everything was normal.

They looked at me like I was crazy. They asked if I take Motrin frequently or drink lots of caffeine. Which I didnt do any of that frequently.

It was the lovely Lyme disease!I still get it,hopefully it doesnt get worse with Zith.

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