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» LymeNet Flash » Questions and Discussion » Medical Questions » Genetic problems ...MTHFR etc.

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Author Topic: Genetic problems ...MTHFR etc.
Marnie
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SOMEDAY...we ALL WILL know our genetic code and will be advised to make NUTRITIONAL adjustments based on our genetic code.

Hey...MTHFR problem...take Rx Deplin or OTC Folo Pro because you GENETICALLY can't PROCESS folic acid to its useful form, etc. to LOWER toxic homocysteine.

THEN throw in exposure to environmental toxins OR, worse yet...pathogens and this totally throws off the picture.

Let me leave you with one statement...

"Alkalinize or die."

Our blood pH is supposed to be slightly alkaline. Cancer and lyme disease, et al THRIVE in an acidic environment.

Doubt? Google this: sodium bicarbonate cancer.

Love ya all! Keep hope alive.

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steve1906
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Sodium Bicarbonate
Other common name(s): Simoncini Cancer Therapy, baking soda

Scientific/medical name(s): NaHC03

Description
Sodium bicarbonate, also known as baking soda, is promoted by some alternative practitioners as a cancer treatment. This treatment is based on the theory that cancer is caused by a form of yeast infection and that sodium bicarbonate can kill the yeast. This claim is not supported by science or clinical evidence and is contrary to widely-accepted basic facts of oncology and microbiology.

Sodium bicarbonate is used as a conventional treatment for disorders in which the blood is too acidic. It is also used as an over-the-counter remedy for heartburn.

Overview
Available scientific evidence does not support claims that cancer is caused by infection with a type of yeast known as Candida albicans. Available scientific evidence also does not support the idea that sodium bicarbonate works as a treatment for any form of cancer or that it cures yeast or fungal infections.

There is substantial evidence, however, that these claims are false. Although sodium bicarbonate is safe when used in proper doses and as directed as a conventional treatment, high doses can cause serious problems or even death.

How is it promoted for use?
Sodium bicarbonate is promoted by some alternative practitioners, especially Dr. Tullio Simoncini, as a cure for all types of cancer. This claim is made on several Web sites, in videos of Dr. Simoncini posted on the Internet, and in a book written by Dr. Simoncini.

What does it involve?
Sodium bicarbonate is given by some alternative practitioners by mouth (orally) or into a vein (intravenously). It is also given intra-arterially (into an artery supplying blood to the tumor) and is sometimes given as a solution directly through the trachea (windpipe) into the lungs to treat lung cancer.

What is the history behind it?
The main proponent of sodium bicarbonate as an alternative cancer treatment is Tullio Simoncini, MD. Information on the Internet describes how Dr. Simoncini concluded that cancer is caused by Candida albicans and can be cured with baking soda. The sequence of events and timeline are not described in detail.

According to the Cancer Treatment Watch Web site, "[Dr. Simoncini] has been using unsubstantiated cancer treatments for 15 years… in 2003, his [Italian] license to practice medicine was withdrawn, and in 2006 he was convicted by an Italian judge for wrongful death and swindling… This has not stopped him from continuing to provide his controversial treatments, not only in Italy, but apparently also in foreign countries, such as the Netherlands." (Koene, Jitta. 2008)

What is the evidence?
No peer-reviewed articles in medical journals were found supporting the theory that cancer is caused by a fungus infection or a yeast infection. Available peer-reviewed medical journals do not support claims that sodium bicarbonate works as a cancer treatment.

Scientists require certain kinds of evidence to support claims that a kind of germ causes a certain disease. The first requirement is that the germ should be present in all cases of the disease. Simoncini claims that all tumors contain fungi.

But these fungi have not been found in tumors when biopsies are examined by methods capable of revealing fungi in infected tissue. Another requirement is that infecting laboratory animals with the germ should cause the disease. Infections can develop in animals that are exposed to Candida albicans, but there are no credible reports that this exposure or infection causes cancer.

Finally, when researchers remove diseased tissue from infected laboratory animals, they should be able to recover the germs and grow them in laboratory dishes. There are no reports in scientific journals that this has been observed for Candida albicans and cancer of experimental animals.

A number of Web sites propose various reasons people believe there is a connection between fungus and cancer (for example, that Candida albicans can cause serious infections, and that cancer is a serious disease). However, none of these Web sites show scientific evidence supported by credible experiments or clinical trials.

Fungal infection deep in the body is a serious health problem that can be fatal. Although a number of antifungal drugs are available to treat these infections, there is no evidence that sodium bicarbonate can. There is no evidence that most people with cancer have any deep tissue yeast or fungal infections. People whose immune systems are weakened by high doses of chemotherapy can sometimes contract these kinds of infections.

While antifungal drugs can often cure the infection, there is no evidence that antifungal treatment causes the patients' tumors to shrink. If this had happened, the doctors caring for these patients would have been likely to report it in medical journals.

Some people with cancer have other health conditions for which sodium bicarbonate is used. But, again, there is no evidence that sodium bicarbonate has caused their tumors to shrink.

Chewable sodium bicarbonate tablets or powder are a common over-the-counter treatment that is used to neutralize stomach acid that causes heartburn. Intravenous sodium bicarbonate is used as a conventional treatment to reduce acidity of blood in serious conditions like shock, severe dehydration, and uncontrolled kidney failure or diabetes.

Are there any possible problems or complications?
This substance may not have been thoroughly tested to find out how it interacts with medicines, foods, herbs, or supplements. Even though some reports of interactions and harmful effects may be published, full studies of interactions and effects are not often available. Because of these limitations, any information on ill effects and interactions below should be considered incomplete.

In general, oral and intravenous treatment with sodium bicarbonate that is given for the right reasons and in proper doses is considered safe. Concern has been raised that the same substance can be dangerous in other medical situations. The Cancer Treatment Watch Web site quotes the Netherlands Health Inspectorate:

… there are no scientific data that justify the administration of sodium bicarbonate to patients with cancer… the administration of sodium bicarbonate even has risks for patients with high blood pressure, patients with diseases of lungs, heart, or kidneys and for patients with cancer.

This is certainly the case if a number of specific blood levels are not monitored daily before, during and after the treatment. The balance of the body can become completely disturbed when large amounts are administered. In severely ill patients, this may lead to organ damage. In sick people, there is in fact irresponsible health care if this product is administered without monitoring. (2008)

http://www.cancer.org/treatment/treatmentsandsideeffects/complementaryandalternativemedicine/herbsvitaminsandminerals/sodium-bicarbonate

Steve

--------------------
Everything I say is just my opinion!

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girl
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I was just thinking that sodium bicarbonate would probably help break up biofilm.

I have mixed thoughts on the whole pH issue since certain parts of the body are acidic and other parts alkaline.

Antibiotics will kill off all the acid producing bacteria (the bad and the good) and so this environment will set the stage for Candida, which likes an alkaline environment.

I guess it depends on if you're talking about the gut or the blood pH, but how to keep the gut slightly acidic while keeping the blood alkaline? And then if you've got Candida in the blood, doesn't that complicate things? See my confusion? [Smile]

PS ~ if you have not heard of "ReMag" magnesium yet, check it out! I'm surprised you are not the "inventor" of it.

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Marnie
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Actually..Candida albicans...uhm...BBB compromised due to inflammatory cytokines...

Caprylic acid (component in virgin coconut oil) is one of the SATURATED FATTY MEDIUM CHAIN FATTY ACIDS in the "medicinal food" $$$ called Axona for AD. It is the "active component" according to the pharm. website.

ALL components in VCO (virgin coconut oil) are KNOWN anti-bacterial, anti-viral, anti- fungus.

Ever watch "Survivor"? There is a REASON why they "survive" on coconut milk!

SUPPOSEDLY SATURATED FATS ARE NOT GOOD FOR US.

Wanna bet?

If YOU chose not to go with Prozac, CONSIDER PLP (active form of B6), 50mg + 100mg of 5HTP daily.

Lecithin (choline) will reverse a fatty liver. Lecithin is in many foods. It is a "fat emulsifier"...breaks up fats. It is in chocolate to make it "smooth".

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girl
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Ooh.. compromised!? Interesting.

Yep. I'm starting on another regimen of my Nutiva Extra Virgin organic coconut oil tonight. In addition to the tsp of oil, I will add one drop of clove essential oil and one drop of lemongrass essential oil - both known to kill the biofilm form of "Candida" - and go from there.

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Marnie
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Biofilms are knocked out with ultrasound...

Dental research proves.

Rife...UHM...

Lemongrass...curious...researched it a long time ago...powerful.

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girl
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Yes! I know. It is powerful. Have to be *really* careful and "respect the drops" - and make sure to take it with enough coconut oil, have a glass of water on hand..

Check this out.

http://gotmag.org/mg-deficiency-affects-mthfr-really/

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Marnie
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Look very very closely at the nutrients in eggs...ya...good old eggs...

OVER EASY to preserve the MANY nutrients in the YOLK...important to cook the "white".

Our blood is SUPPOSED TO BE SLIGHTLY ALKALINE.

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Marnie
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For newbies...saturated fats are LOADED with hydrogen.

CoQ10 carries hydrogen INTO the cells. We make CoQ10 when we...exercise...but given lyme...who can?...Besides...ALL of our enzymes need Mg to be made and we KNOW, for fact, Mg levels plummet at the outset of lyme.

Many of our cells are "hydrogen powered"...so I read many moons ago.

Statin drugs (to lower cholesterol), Propanolol, et al DEPLETE Co Q10...

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girl
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... and actually *cause* heart disease instead of prevent it.
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girl
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Do any of you guys take CoQ10? Upon a search, I'm reading that there are different forms, pill, liquid, raw... which form is most effective? More bang for your buck? Food?
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Marnie
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YUP.
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Lymetoo
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I take CoQ10.

--------------------
--Lymetutu--
Opinions, not medical advice!

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girl
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10mg? Take it with coconut oil!
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girl
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Marnie ~ Do you have any thoughts on chemical sensitivity?
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Lymetoo
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I think it's 100mg. I'll take it with oil next time. Why does that help?

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--Lymetutu--
Opinions, not medical advice!

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Marnie
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Genetic predisposition first...unable to tolerate chemicals.

Example...I can eat foods seasoned with MSG with no problems...my son cannot...absolutely NOT!

http://www.webmd.com/allergies/multiple-chemical-sensitivity 2013...

Depression and anxiety mentioned in the link above REALLY peaked my interest.

Now we're talking about 5HT3 receptors and

vestibular suppressants.

Glutamate excess is the underlying problem...either convert it to GABA (IMO, best route) or increase anti-inflammatory serotonin -> amti-oxidant, melatonin.

Some of the vestibular suppressants (cranial nerve #8) include such drugs as: Zofran, Klonopin, Xanax and Ativan.

Zofran is a 5HT3 (tryptophan) receptor *antagonist*. Serotonin stays higher longer... It is used for N/V in chemo and hyperemesis of pregnancy, but get this...it is given post op for chills...it appears that receptor is involved in...

thermoreguation.


How many persons do you know who complain of feeling cold (when others are dying of the heat)?


We normally associate Klonopin with anxiety...to lower, but it can act as an antidepressant too. PubMed...years ago.

Chemoreceptor trigger zone is sensitive to chemical stimuli...

Substance P is THE ultimate trigger, but other "chemicals" are involved.

http://en.wikipedia.org/wiki/Chemoreceptor_trigger_zone

I've just been studying that...

Substance P...

Wikipedia...

it is found in the brain and spinal cord, and is associated with inflammatory processes and pain.

Now...logic says if someone has a lot of inflammation and pain perhaps they are more sensitive to chemicals...

?

Some persons (genetically and by choice) are glutamate (accelerator) and epinephrine (= adrenaline) "junkies".

They are typically type A persons...wired.

Caffeine...Starbucks lovers and nicotine get them going...up goes the brain accelerator, glutmate.

Then they HAVE to unwind...have a beer...convert that glutamate to GABA (brake).

The conversion (very simplified):

Glutamate <-> GABA requires B6...active form is PLP.

I THINK many Americans are B6 deficient...we KNOW our older population is.

P.S. The acids work best in an alkaline environment. Get your blood alkaline and *then* add good old VCO - saturated medium chain fatty acids.

How...because our STOMACH HAS to be acidic to digest foods.

Bypass the stomach. Take a BATH in mineral salts.

AlkaBath?

[ 01-31-2014, 12:34 AM: Message edited by: Marnie ]

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girl
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Soo.. eating cultured vegetables would help increase serotonin since 90% of the serotonin is made in the gut AND those good bacteria help produce B6, too. Maybe go after it both ways? (the serotonin and the glutamate)

The vestibular supplements are out but now that you mention it, when I DID take them, I think my MCS was gone. Only problem was I had to keep upping the dose to get the same effect and it finally got to a point to where I had side effects of short term memory loss and depression (Ativan). I wonder if a 2mg Valium would do?

As for thermoregulation you know what is helping me *feel* warmer? ReLyte "picoionic" minerals. Similar to the ReMag I mentioned to you before. There are only 12 minerals so I like to add celtic salt to water in addition to the ReLyte, but it helps. It works so quickly I can always tell when it's time for my dose because my toes will get cold.

Dang. I don't want to be a glutamate junkie if that's the prob! It takes *very little* starbucks to get me going. I'm talking a few SIPS of a coffee and the adrenaline kicks in. Some would see this as a good thing but no...

To unwind, seems like a red potato or even a bowl of quinoa will help me. I wonder how quinoa affects glutamate. Interesting. So it sounds like a lot of this can be 'controlled' through diet somehow, to some extent. Need to get on a regular regimen and see.. and maybe add in some B6 in the pill form. I've heard some of it is made with formaldehyde and need to find a decent source for it. In higher doses it gives me nightmares. Maybe I can get enough through food. I eat the cultured vegetables with every meal.

I was hoping ReMag (magnesium) would help with the chemical sensitivity because my theory was it was some kind of screw up in the HPA-axis that causes it. I didn't always used to be sensitive. It wasn't until Bb turned on some kind of gene that made me not be able to detox as effectively. Something to that effect. And untimately the MOLD exposure after the Bb is what caused it, or kicked it in. Bb "opened the door" to these other illnesses, like mold. I'm just wondering how to reverse it. Seems the simple answer would be to turn those genes back off somehow.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198864/

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girl
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PS. I have noticed that dairy makes it flare, too, wonder if the dairy contains glutamate. Will have to look and see.
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Catgirl
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quote:
Originally posted by Marnie:
"Alkalinize or die."

Our blood pH is supposed to be slightly alkaline. Cancer and lyme disease, et al THRIVE in an acidic environment.

Ditto!

--------------------
--Keep an open mind about everything. Also, remember to visit ACTIVISM (we can change things together).

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seekhelp
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Been eating coconut milk a LOT lately...zero improvement in health. Not sure it is so anti-bacterial, anti-viral, or others.
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girl
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Coconut MILK? Like out of the can?
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Marnie
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VCO...virgin coconut OIL has saturated medium chain fatty acids all of which are known anti-bacterial, anti-viral and anti-fungal.

It takes TIME... and should not be overdone!

A doc (woman) in Florida is reversing her husband's AD by giving him 3 tablespoons of VCO daily.

That would be hard for me to do...sorta like trying to swallow Crisco.

But I get the "healthy" connection.

And understand why the participants on "Survivor" drink coconut milk (and eat the coconut "meat" inside the shell?).

When looking at the nutrients in coconut meat and coconut milk... one nutrient that stood out... manganese.

Which in a jam can substitute for magnesium.

Like everything else...some is good, too much is not.

Skim this:

http://www.organicfacts.net/health-benefits/minerals/health-benefits-of-manganese.html

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