LymeNet Home LymeNet Home Page LymeNet Flash Discussion LymeNet Support Group Database LymeNet Literature Library LymeNet Legal Resources LymeNet Medical & Scientific Abstract Database LymeNet Newsletter Home Page LymeNet Recommended Books LymeNet Tick Pictures Search The LymeNet Site LymeNet Links LymeNet Frequently Asked Questions About The Lyme Disease Network LymeNet Menu

LymeNet on Facebook

LymeNet on Twitter




The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

LymeNet Flash Discussion
Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive


The Lyme Disease Network is a non-profit organization funded by individual donations.

LymeNet Flash Post New Topic  New Poll  Post A Reply
my profile | directory login | register | search | faq | forum home

  next oldest topic   next newest topic
» LymeNet Flash » Questions and Discussion » Medical Questions » CD8-Cd57? Lower after a year?

 - UBBFriend: Email this page to someone!    
Author Topic: CD8-Cd57? Lower after a year?
jennyfromtheblock
Member
Member # 43805

Icon 1 posted      Profile for jennyfromtheblock     Send New Private Message       Edit/Delete Post   Reply With Quote 
Last year I was dx with chronic lyme. after a few months, they took my cd57 and it was normal. Doc wanted to take me off meds b/c he was thinking it could be something other than lyme. I said, no. I am getting better. He said, that is a whole other story, that I could have a normal cd 57 with lyme too.

Now, a year later he tests my levels, and I am a 1% and a 19! What in the world? How is it going down instead of up? I am getting better, but still pretty sick.

What does this mean?

--------------------
celiac dx 2012
pancreatic neuroendocrine tumor dx 2012
lyme dx 2/14
poss igm wb, neg igg wb - Igenex/CDC

Posts: 85 | From south shore | Registered: May 2014  |  IP: Logged | Report this post to a Moderator
TNT
Frequent Contributor (1K+ posts)
Member # 42349

Icon 1 posted      Profile for TNT     Send New Private Message       Edit/Delete Post   Reply With Quote 
What was your doc considering normal? Was your count previously under 120? If so, that is definitely not normal.

There is a difference of opinions between lyme docs about what normal is. I would say less than 200 is not "normal" (generally, a healthy person's would be around 200).

Posts: 1308 | From Eastern USA | Registered: Oct 2013  |  IP: Logged | Report this post to a Moderator
jennyfromtheblock
Member
Member # 43805

Icon 1 posted      Profile for jennyfromtheblock     Send New Private Message       Edit/Delete Post   Reply With Quote 
I've tried to find my old labs, just too tired to look past the end of my nose right now. I know it was within range. But I don't remember what.

Enough for him to consider it could be something else. Which it clearly wasn't. Due to me getting better on the meds.

So I accepted that my CD 57 didn't mean much for me. So why is it so low now and not then?

--------------------
celiac dx 2012
pancreatic neuroendocrine tumor dx 2012
lyme dx 2/14
poss igm wb, neg igg wb - Igenex/CDC

Posts: 85 | From south shore | Registered: May 2014  |  IP: Logged | Report this post to a Moderator
BoxerMom
Frequent Contributor (1K+ posts)
Member # 25251

Icon 1 posted      Profile for BoxerMom     Send New Private Message       Edit/Delete Post   Reply With Quote 
Did he use the same lab each time? LabCorp and Quest use different scales. LabCorp tends to be more consistent and more accurate.

He may have used a different lab entirely.

It's common for the CD57 to vary during treatment. Chronic Infections, neurotoxins and abx all suppress immunity. Neurotoxins are the big one, so if you are in a herxing phase, your immune cell numbers can plummet.

Don't panic. This is normal. Remember to do your detox. And don't test too frequently. You'll just freak out.

My CD57 has been to some dangerous places, but is now normal after many years of treatment. It's actually Babesia treatment and heavy detox with Cholestyramine that brought it back up, so the neurotoxins were huge for me.

Just keep plugging along. You'll get there.

--------------------
 - Must...find...BRAIN!!!

Posts: 2867 | From Pacific NW | Registered: Apr 2010  |  IP: Logged | Report this post to a Moderator
Phoiph
Frequent Contributor (1K+ posts)
Member # 41238

Icon 1 posted      Profile for Phoiph     Send New Private Message       Edit/Delete Post   Reply With Quote 
One of the ways Lyme invades the immune system and becomes established is to upset the balance between Th1 (including Natural Killer cells) and Th2, and shifting to a Th2 dominant response.

Certain antibiotics can also reduce your Th1/Natural Killer Cell production, including:

Doxycycline
Zithromax
Ampicillin
Cefoxitin/Gentamycin

For example, there is actually a "doxycycline protocol" that is used by fertility specialists to suppress the Th1/NK cell response in an effort to reduce the chances of the body rejecting the embryo:

"...Studies have shown that certain antibiotics will down-regulate the negative effects of natural killer cells, cytokines gamma interferon and TNF alpha to support nurturing and implantation of the embryo. Other antibiotics, however, can cause an increase in the natural killer cells and cytokines thereby moving patients more to the TH1 side, making the uterine environment more hostile. The antibiotics that appear to promote implantation by moving to the TH2 state are: Ampicillin Cefoxitin/Gentamycin Doxycycline Zithromax..."

http://www.goivf.com/treatment-options/immunology/

Here are links to 2 articles that describe factors affecting immune involvement in chronic illness:

http://www.drkaslow.com/html/immune_restoration.html

http://www.lymebook.com/lyme-disease-nk-natural-killer-cells

Posts: 1732 | From Earth | Registered: Jul 2013  |  IP: Logged | Report this post to a Moderator
jennyfromtheblock
Member
Member # 43805

Icon 1 posted      Profile for jennyfromtheblock     Send New Private Message       Edit/Delete Post   Reply With Quote 
thank you! I will check into the labs. I have a feeling they were both Lab Corp

--------------------
celiac dx 2012
pancreatic neuroendocrine tumor dx 2012
lyme dx 2/14
poss igm wb, neg igg wb - Igenex/CDC

Posts: 85 | From south shore | Registered: May 2014  |  IP: Logged | Report this post to a Moderator
   

Quick Reply
Message:

HTML is not enabled.
UBB Code is enabled.

Instant Graemlins
   


Post New Topic  New Poll  Post A Reply Close Topic   Feature Topic   Move Topic   Delete Topic next oldest topic   next newest topic
 - Printer-friendly view of this topic
Hop To:


Contact Us | LymeNet home page | Privacy Statement

Powered by UBB.classic™ 6.7.3


The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA


| Flash Discussion | Support Groups | On-Line Library
Legal Resources | Medical Abstracts | Newsletter | Books
Pictures | Site Search | Links | Help/Questions
About LymeNet | Contact Us

© 1993-2020 The Lyme Disease Network of New Jersey, Inc.
All Rights Reserved.
Use of the LymeNet Site is subject to Terms and Conditions.