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» LymeNet Flash » Questions and Discussion » Medical Questions » Amphotericin B

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Author Topic: Amphotericin B
terv
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Has anyone used amphotericin B and if so what form?

I have candida glabrata. I have tried boric acid and voriconazole and neither worked.

After reading about amphotericin B , it sounds pretty toxic plus hard to absorb orally.

If you used it what did you use it for and did it work?

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Lymetoo
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I think it's pretty scary stuff.

Diflucan or Sporanox won't work?

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--Lymetutu--
Opinions, not medical advice!

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terv
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No. I have tried both. It is resistant to azole drugs.
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Lymetoo
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How bad is the candida? You've tried natural things too?

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--Lymetutu--
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sammy
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Where in the body was the Candida glabrata found? What kind of test was done? Any other bacteria, fungi, virus, or parasites identified? And was there a significant amount or minor amount of Candida glabrata found?

Candida glabrata is frequently an environmental contaminant. It can even show up in small amounts on GI tissue & fluid biopsies (scope contamination).

It sounds like you have a lot of unanswered questions, write them all down, & please share your concerns with your doctor.

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terv
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It was found in the vagina. Only symptom is itching - no discharge or anything else. I had tried many rounds of monistat and then difulcan and when I couldnt get it resolved I went to gyn.

I dont know how bad it is. All I know is that it has been going on for at least 2 years. I just ignored it assuming that some azole drug would wipe it out and when they didn't i went to gyn.

She swabbed and ran a whole panel of everything that could be growing in there and glabrata was the only thing that came back positive. Amazing that I didnt have albacans.

Did 2 weeks of boric acid and that didnt resolve it so she referred me to another doctor who has a small group of patients with it.

Called for an appt and they dont take my insurance which is fine. I told them I would pay cash. They apparently cant do cash only because they dont know what is going to happen in the appt. I need to try again.

Gyn also gave me a name of infectious disease dr who is not well liked within our lyme community so he is out.

LLMD gave me voriconazole which he seemed confident would wipe it out. Barely touched it if I am going by symptoms. I have a call into him. I mentioned the amp B at my appt and he didn't say anything and gave me the voriconazole instead.

Oxalate Facebook group uses large doses of biotin for candida and oxalates. That is the only natural remedy I have tried. I had started using it for candida and noticed an improvement in my white coated tongue. The itching continued though. Anyway I ended up with a diaphragm spasm for 4 months. I removed the biotin and it got a lot better within a week. I dont understand that unless it had to do with an oxalate dump.

I am back to slowly adding in the biotin. Maybe it will hit the glabrata along with albicans.

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Lymetoo
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I would try anything before giving in to the Amp B .. have you read about it?

Yes, try upping the biotin slowly. It really helps me.

You could also try probiotics vaginally. (get your good bacteria to take care of the bad)

Best of luck with this!

--------------------
--Lymetutu--
Opinions, not medical advice!

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terv
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Yes I did read about it and was terrified. I also am not happy that there really isn't anything out there to treat this.

It was interesting to see how much biotin helped my yeast. I just hope it will work on the glabrata version.

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Pocono Lyme
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I did it for sinusitis.
I got the IV form, drew it up in a syringe and mixed in a bottle of sterile saline.

I did sinus baths with it. Maybe you could use it this way to douche.

I didn't experience any negative effects. I hope you get relief soon.

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2 Corinthians 12:9-11


9 But he said to me, �My grace is sufficient for you, for my power is made perfect in weakness.� Therefore I will boast all the more gladly about my weaknesses, so that Christ�s power may rest on me.

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terv
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That's interesting. I searched around and they have used suppositories. 70% success rate.
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Lymetoo
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Good news!

--------------------
--Lymetutu--
Opinions, not medical advice!

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