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» LymeNet Flash » Questions and Discussion » Medical Questions » Ehrlichia in children - treatment options

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Author Topic: Ehrlichia in children - treatment options
Tony1996
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My LLMD has prescribed Doryx for my 8 year old because she tested positive for Ehrlichia. I questioned this since Dr. B's guidelines state Doxy should not be used on children. My LLMD says he consults with Dr J in CT and this is standard. I've read on this board that Doxy/Doryx should not be given to children under 10. [confused] Can anyone share their experiences or do you have any suggestions?
Posts: 21 | From York, PA | Registered: Jan 2002  |  IP: Logged | Report this post to a Moderator
orrn
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My daughter is 6 years old. We were diagnosed with LD 3 years ago. She actually went symptom

free for nearly 6 months, but symptoms started coming back. Our LLMD put her back on the

antibiotic that she was taking right before her "remission". She was having such severe

symptoms that he switched her to another. In our last office with him he said we could try

Doxy, but only for a short period of time to prevent the discoloration of her teeth. We

haven't tried it yet, but I am open to the option if we need it.

What are your daughter's symptoms? I haven't talked with alot of parents of kids with LD or tick related diseases.

I wish you luck! Take care. Please feel free to e-mail me if you want to.

orrn

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Tony1996
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We weren't really watching symptoms. We found the deer tick on her and a week or two later the bulls eye rash appeared. While she was being treated for Lyme, the LLMD tested her for the co-infections. Ehrlichia was the only one that came back positive.
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CaliforniaLyme
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Don't have to use Doxy!!!!

1: Pediatrics. 2003 Sep;112(3 Pt 1):e252-3. Related Articles, Links


Successful treatment of human granulocytic ehrlichiosis in children using rifampin.

Krause PJ, Corrow CL, Bakken JS.

Department of Pediatrics, University of Connecticut School of Medicine and Connecticut Children's Medical Center, Hartford, USA.

Human granulocytic ehrlichiosis (HGE) is an emerging tick-borne infectious disease caused by Anaplasma phagocytophilum. Clinical features include a flu-like illness that usually resolves within 1 week. More serious infection may occur that requires hospital admission or culminates in death. Doxycycline is the treatment of choice for HGE but may cause permanent staining of teeth in children younger than 8 years of age. We report successful treatment of HGE with rifampin in 2 children, 4 and 6 years old. A course of rifampin for 5 to 7 days should be considered in children younger than 8 years of age who experience non-life-threatening A phagocytophilum infection.

Publication Types:
Case Reports

PMID: 12949322 [PubMed - indexed for MEDLINE]

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Posts: 5639 | From Aptos CA USA | Registered: Apr 2005  |  IP: Logged | Report this post to a Moderator
lou
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Don't know which ehrlichia you are talking about, but here is another abstract on abx for this disease:

Antimicrob Agents Chemother. 2003 Jan;47(1):413-5.

Antibiotic susceptibilities of Anaplasma (Ehrlichia) phagocytophilum strains from various geographic areas in the United States.

Maurin M, Bakken JS, Dumler JS.

Unite des Rickettsies, Universite de la Mediterranee, Faculte de Medecine, Marseille, France.

We tested the antibiotic susceptibilities of eight strains of Anaplasma phagocytophilum (the agent of human granulocytic ehrlichiosis) collected in various geographic areas of the United States, including Minnesota, Wisconsin, California, and New York. The results are homogeneous and show that doxycycline, rifampin, and levofloxacin are the most active antibiotics against these strains in vitro.

PMID: 12499227 [PubMed - indexed for MEDLINE]

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