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» LymeNet Flash » Questions and Discussion » Medical Questions » Mepron and Doxy Interaction

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Author Topic: Mepron and Doxy Interaction
jwenny
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Member # 8831

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I am currently taking 400 mg/day doxy with mepron/zith to treat both Bb and babesia at the same time. However, I ran across the following link and am a bit concern about it:

http://www.drugs.com/MTM/M/Mepron.html

What other drugs will affect atovaquone?
* Before taking atovaquone, tell your doctor if you are taking any of the following medicines:
rifampin (Rifadin, Rimactane, others)
rifabutin (Mycobutin)
tetracycline (Sumycin, Panmycin, others); or
metoclopramide (Reglan).
* You may not be able to take atovaquone, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
* Drugs other than those listed here may also interact with atovaquone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines

Can any share some light on this? For instance, will this reduce the concentration of Mepron?

Thanks!

Posts: 187 | From Gaithersburg, Maryland | Registered: Feb 2006  |  IP: Logged | Report this post to a Moderator
suki444
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My LLMD does not use doxy with Atovaquone ... certainly it is not a combo he has even put me on, he uses macrolide antibiotics with Mepron usually.

Emma

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SForsgren
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My LLMD has me on doxy while on Mepron.

--------------------
Be well,
Scott

Posts: 4617 | From San Jose, CA | Registered: Jul 2005  |  IP: Logged | Report this post to a Moderator
jwenny
LymeNet Contributor
Member # 8831

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hey everyone,

This is important.

I think I found what I'm looking for. So for all those taking Tetra/Doxy with Mepron including myself, please take a look at these links. Apparently, atovaquone levels are reduced by 40% with Tetra/Doxy.

http://www.pubmedcentral.gov/articlerender.fcgi?artid=127192

http://www.drugs.com/MTM/M/Mepron.html

http://www.fpnotebook.com/ID174.htm

Posts: 187 | From Gaithersburg, Maryland | Registered: Feb 2006  |  IP: Logged | Report this post to a Moderator
   

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