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» LymeNet Flash » Questions and Discussion » Medical Questions » Traditional Herbal Medicines for Malaria

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Author Topic: Traditional Herbal Medicines for Malaria
jwenny
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Found this comparison interesting....

http://www.bmj.com/cgi/content/full/329/7475/1156/TBL3

Which one looks like the winner here?

Posts: 187 | From Gaithersburg, Maryland | Registered: Feb 2006  |  IP: Logged | Report this post to a Moderator
Dave6002
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Here is the link for the full-text PDF file:

http://www.bmj.com/cgi/reprint/329/7475/1156.pdf

Posts: 1078 | From Fairland | Registered: Apr 2006  |  IP: Logged | Report this post to a Moderator
Dave6002
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In vitro and in vivo antiplasmodial activity of Momordical balsamina alone or in a traditional mixture
Author(s): Benoit-Vical F (Benoit-Vical, F.), Grellier P (Grellier, P.), Abdoulaye A (Abdoulaye, A.), Moussa I (Moussa, I.), Ousmane A (Ousmane, A.), Berry A (Berry, A.), Ikhiri K (Ikhiri, K.), Poupat C (Poupat, C.)
Source: CHEMOTHERAPY 52 (6): 288-292 2006

Abstract: Background: Because of the dramatic situation of malaria in Africa, there is an

urgent need to find new and cheap drugs, such as herbal medicines. Here we report the

study of the in vitro and in vivo antimalarial activity of Momordica balsamina alone or in

a traditional mixture used in Niger. Methods: Extracts were obtained with different

solvents and tested in vitro on Plasmodium falciparum and in vivo on Plasmodium

vinckei. Results: The best extracts are methanolic and present promising results in vivo

by intraperitoneal and oral administration. Conclusion: The antimalarial activity of M.

balsamina, traditionally used in Niger, is confirmed in vitro and in vivo without any

toxicity in healthy mice.


Addresses: Benoit-Vical F (reprint author), CHU Rangueil, Serv Parasitol, 1,Ave Poulhes,TSA50032, FR-31059 Toulouse 9, France

CHU Rangueil, Serv Parasitol, FR-31059 Toulouse 9, France
CHU Rangueil, Lab Chim Coordinat, CNRS, UPR8241, F-31054 Toulouse, France
Museum Natl Hist Nat, Dept Regulat Dev Divers Mol, F-75231 Paris, France
CNRS, Inst Chim Subst Nat, Gif Sur Yvette, France
Univ A Moumouni, Dept Chim, Fac Sci, Niamey, Niger
E-mail Addresses: [email protected]

Posts: 1078 | From Fairland | Registered: Apr 2006  |  IP: Logged | Report this post to a Moderator
catalysT
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Ohh nice one, thanks jwenny!

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Posts: 242 | From South NJ | Registered: Dec 2006  |  IP: Logged | Report this post to a Moderator
   

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