posted
Says mycoplasma can establish chronic infections and form biofilms.
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Being Pathogenic, Plastic, and Sexual while Living with a Nearly Minimal Bacterial Genome
Pascal Sirand-Pugnet1,2, Carole Lartigue1,2�a, Marc Marenda3�b, Daniel Jacob4, Aur�lien Barr�4, Val�rie Barbe5, Chantal Schenowitz5, Sophie Mangenot5, Arnaud Couloux5, Beatrice Segurens5, Antoine de Daruvar4, Alain Blanchard1,2, Christine Citti3*
1 Universit� Bordeaux 2, UMR1090, Villenave d'Ornon, France, 2 INRA, UMR1090, Villenave d'Ornon, France, 3 INRA, ENVT, UMR1225, Toulouse, France, 4 Centre de Bioinformatique de Bordeaux, Universit� Bordeaux 2, Bordeaux, France, 5 Genoscope, Centre National de S�quen�age, Evry, France
Author Summary
Mycoplasmas are cell wall-lacking prokaryotes that evolved from ancestors common to Gram-positive bacteria by way of massive losses of genetic material. With their minimal genome, mycoplasmas are considered to be the simplest free-living organisms, yet several species are successful pathogens of man and animal.
In this study, we challenged the commonly accepted view in which mycoplasma evolution is driven only by genome down-sizing. Indeed, we showed that a significant amount of genes underwent horizontal transfer among different mycoplasma species that share the same ruminant hosts.
In these species, the occurrence of a genetic element that can promote DNA transfer via cell-to-cell contact suggests that some mycoplasmas may have retained or acquired sexual competence.
Transferred genes were found to encode proteins that are likely to be associated with mycoplasma-host interactions. Sharing genetic resources via horizontal gene transfer may provide mycoplasmas with a means for adapting to new niches or to new hosts and for avoiding irreversible genome erosion.
treepatrol
Honored Contributor (10K+ posts)
Member # 4117
posted
yep
-------------------- Do unto others as you would have them do unto you. Remember Iam not a Doctor Just someone struggling like you with Tick Borne Diseases.
Jellybelly
Frequent Contributor (1K+ posts)
Member # 7142
posted
Ya, whatever Tree said.
Posts: 1251 | From california | Registered: Apr 2005
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Beverly
Frequent Contributor (5K+ posts)
Member # 1271
posted
Hmmm, interesting, thank you for the link.
Posts: 6626 | From Michigan | Registered: Jun 2001
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Jellybelly
Frequent Contributor (1K+ posts)
Member # 7142
posted
In reality, mycoplasma was the first thing I ever had show up as positive. That was about 6 years ago. Fermentans and pnuemonia.
My doc told me a long time ago that they can forever adapt, changing into whatever is needed, thus the name Incognitus.
I was started way back when on abx for the Mycos. It may be possible that what ailes me the most is the mycos and that may be why I have made such progress without massive amounts of abx. I don't really have any idea though, I just know I have Lyme and Mycos....nasty stuff.
Posts: 1251 | From california | Registered: Apr 2005
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