Also known as Dragon's Blood. Great name, eh?
I am feeling a bit of an intuitive push to take this, so I got some and just started taking it. I was encouraged to see it come up in connection with treating Lyme and also it's seemingly "anti everything" properties (anti-fungal, anti-viral...etc.)
But what struck me most was that some people had reported success using it for nerve pain. Oh lawdy would that be nice.
Did a search on Lymenet and nothing came up -- so was wondering if anyone out there had tried it and if so what your experience was.
The obscure we see eventually. The completely obvious, it seems, takes longer. --- Edward R. Murrow Posts: 923 | From California | Registered: Aug 2005
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Pubmed search for sangre de grado
1: Miller MJ, Bobrowski P, Shukla M, Gupta K, Haqqi TM. Chondroprotective effects of a proanthocyanidin rich amazonian genonutrient reflects direct inhibition of matrix metalloproteinases and upregulation of IGF-1 production by human chondrocytes. J Inflamm (Lond). 2007 Aug 14;4(1):16 [Epub ahead of print] PMID: 17697350 [PubMed - as supplied by publisher]
2: Tran CD, Butler RN, Miller MJ. The role of Amazonian herbal medicine Sangre de Grado in Helicobacter pylori infection and its association with metallothionein expression. Helicobacter. 2006 Apr;11(2):134-5. No abstract available. PMID: 16579844 [PubMed - indexed for MEDLINE]
3: Milanowski DJ, Winter RE, Elvin-Lewis MP, Lewis WH. Geographic distribution of three alkaloid chemotypes of Croton lechleri. J Nat Prod. 2002 Jun;65(6):814-9. PMID: 12088421 [PubMed - indexed for MEDLINE]
4: Sandoval M, Okuhama NN, Clark M, Angeles FM, Lao J, Bustamante S, Miller MJ. Sangre de grado Croton palanostigma induces apoptosis in human gastrointestinal cancer cells. J Ethnopharmacol. 2002 May;80(2-3):121-9. PMID: 12007701 [PubMed - indexed for MEDLINE]
5: Williams JE. Review of antiviral and immunomodulating properties of plants of the Peruvian rainforest with a particular emphasis on Una de Gato and Sangre de Grado. Altern Med Rev. 2001 Dec;6(6):567-79. Review. PMID: 11804547 [PubMed - indexed for MEDLINE]
6: Miller MJ, Vergnolle N, McKnight W, Musah RA, Davison CA, Trentacosti AM, Thompson JH, Sandoval M, Wallace JL. Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado. J Invest Dermatol. 2001 Sep;117(3):725-30. PMID: 11564183 [PubMed - indexed for MEDLINE]
7: Miller MJ, MacNaughton WK, Zhang XJ, Thompson JH, Charbonnet RM, Bobrowski P, Lao J, Trentacosti AM, Sandoval M. Treatment of gastric ulcers and diarrhea with the Amazonian herbal medicine sangre de grado. Am J Physiol Gastrointest Liver Physiol. 2000 Jul;279(1):G192-200. PMID: 10898763 [PubMed - indexed for MEDLINE]
8: Itokawa H, Ichihara Y, Mochizuki M, Enomori T, Morita H, Shirota O, Inamatsu M, Takeya K. A cytotoxic substance from Sangre de Grado. Chem Pharm Bull (Tokyo). 1991 Apr;39(4):1041-2. PMID: 1893488 [PubMed - indexed for MEDLINE]
9: Vaisberg AJ, Milla M, Planas MC, Cordova JL, de Agusti ER, Ferreyra R, Mustiga MC, Carlin L, Hammond GB. Taspine is the cicatrizant principle in Sangre de Grado extracted from Croton lechleri. Planta Med. 1989 Apr;55(2):140-3. PMID: 2748730 [PubMed - indexed for MEDLINE]
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It does look interesting, Riverspirit, especially for its supposed analgesic effect on neuropathies. It also sounds to be very broad spectrum.
Have you come across any contra-indications/side effects?
Posts: 1647 | From UK | Registered: Nov 2008
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- If tincture and used straight, be aware that this can cause teeth staining. If gums are receeded, the exposed root will be come darker with this. DILUTE to minimize this effect and then, in 3/4 cup of water it should be find.
It can be strong and burn, too, so another reason to dilute if you use tincture. If this comes as capsules, that might be best but often a tincture can get into the blood stream more quickly.
I used this straight in my mouth for a while to help with gum issues. It did that but teeth are much darker and I will not do any chemical whitening as that can be very caustic.
I can't speak to this being any kind of pain reducer as I used it just on my mouth - and it did not help much in that regard with pain and burning. Sea Buckthorn oil was more effective for my mouth in that regard.
Of course, for sytemic pain reduction, this may work. I just never used it for that and my dose would have been just enough to coat my gums.
Even if it stains, used straight on gums with a Q-tip, this is a powerful anti-tartar tool. -
Posts: 48021 | From Tree House | Registered: Jul 2007
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Several years ago I read a lyme protocol that used this as a topical ointment -- I mixed it with some lotion (can't remember the brand) and hubby used a couple of bottles of the herb as a tincture used that way. Don't remember it doing much used that way.
Posts: 7306 | From Martinsville,VA,USA | Registered: Oct 2004
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