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» LymeNet Flash » Questions and Discussion » Medical Questions » Klonopin and Doxycycline or Zithromax

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Author Topic: Klonopin and Doxycycline or Zithromax
CherylSue
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Before I was on Antibiotics I was taking low dose klonopin for sleep. I weaned myself off and was taking burbur drops to relax.

Now I am on doxycycline and may be starting zithromax. I still have trouble sleeping. Can I take klonopin with these meds?

Does anyone have experience with this?

Thanks for your input.

CherylSue

Posts: 1954 | From Illinois | Registered: Aug 2007  |  IP: Logged | Report this post to a Moderator
feelfit
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Hi I take klonopin low dose.25-.50.whil on IV abx.

My primary care doc says it is fine to do so.

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CherylSue
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Thanks for the reply. What ABX are you taking?

Thanks,
CherylSue

Posts: 1954 | From Illinois | Registered: Aug 2007  |  IP: Logged | Report this post to a Moderator
jamescase20
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You know cheryl theres alot of powerful herbs, etc that work great if you take a high enough dose. I find up to 20mg, (safe) of meletonin works great for me.
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CD57
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Yes, you can (but maybe check on drugsdigest.com to be safe).
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lymednva
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I take klonopin and I've been on doxy and clarithromycin, which is a macrolide like zith.

I agree with CD57 that it's a good idea to check fro interactions. You can also ask a pharmacist.

They are the most knowledgeable about such things, and can look it up if they don't know the answer. They are usually happy to do it for their customers.

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Lymednva

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sixgoofykids
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I've taken it with mino, Biaxin, and many other abx ... but not doxy or zith. I'd ask the pharmacist.

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sixgoofykids.blogspot.com

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Cass A
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I'd go with B1 and perhaps B Complex, especially if your sleeplessness is due to continuously thinking about things.

Klonopin is a psychiatric drug that can have serious side effects.

Magnesium also helps for sleeping. It MAY be picked up and used by biofilms, according to posts I've seen here on Lymenet.

Best,

Cass A

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lymebytes
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My husband has taken klon with both, but to be sure check with the pharmacist or here is an durg interaction checker; http://www.drugs.com/drug_interactions.html

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www.truthaboutlymedisease.com

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Keebler
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-

My concern is that klonopin uses the Cytochrome P-450 liver detox pathway - possibly resulting in excess porphryins that can be a problem from too much stress on that pathway, especially for those with chronic illness such as lyme, and CFS.

You might ask your doctor not just about interactions, but how the liver can handle the total load and what you might do for liver support.

Zithromax may cause some ringing in the ears. You might also ask what you can do to prevent that beforehand. Vitamin B6 ?
Vitamin E ?

--

about SECONDARY PORPHYRIA & Cytochrome P-450 pathway in treatment of chronic infection, this article has some good hints - treatment of Cpn seems to mirror that for lyme, so this can be very relevant.

This is hard to read, but if you print it out it's easier.


www.cpnhelp.org/secondaryporphyria

AND

http://tinyurl.com/25ufvx (easier to read but I'm not sure if it is the the exact article as above. Same author and topic.)


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Chia Pet
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Without Klonopin I would never get any sleep.
I take a small dose. .50 mg at night only.
Knocks me right out. I have taken with doxy and zith.

The only thing about Klonopin my doc told me was that it can interfere with REM sleep and offered me a sleeping pill (can't remember which one) that helped increase rem sleep, but I declined it. So far I average about 6 hrs with the klonopin.

During the day, when needed to relax, I use amantilla from Cowden protocol.

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daisys
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cherylsue,
I'm on doxy and klonopin both. I haven't had any problems that could be attributed to taking them together.

I haven't taken zithromax, so can't comment.

Reading this thread has me realizing how strong my sleep disorder is. Not only do I take xyrem, but I was taking 3mg of klonopin for awhile.

With treatment, my sleep has improved. I've dropped down to 2mg of klonopin. I wake up more often, but still manage to get enough sleep, even if it means napping later in the day.

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CherylSue
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Thanks for all your responses. I tried 1/4 tablet of zith again last night, and I've been having crying spells all day. I just can't take it. I'm so sensitive to meds. Doxy, although it upsets my stomach, did the most for me until I plateaued.

I feel awful today.

CherylSue

Posts: 1954 | From Illinois | Registered: Aug 2007  |  IP: Logged | Report this post to a Moderator
   

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