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» LymeNet Flash » Questions and Discussion » Medical Questions » are bacteriostatic abx effective?

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Author Topic: are bacteriostatic abx effective?
cottonbrain
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My LLMD says he believes in treating with bacteriostatic meds rather than bactericidals, that they may take longer but work just as well and are safer.

He has me on:

600 mg zith every other day
100 mg mino every other day
10mg x 2/day benicar
buhner core protocol

I know there's a lot of controversy about benicar -- he has me on it for inflammation, and so far it has helped with my chronic migraines.

I've been on this protocol for six weeks, and i've been herxing the whole time, or else having drug reactions, i dunno which.

is it really possible to kill borrelia (and co's?) with bacteristatics?

all opinions welcome, please!

[ 12. April 2008, 01:22 AM: Message edited by: cottonbrain ]

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adamm
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People herx on them, so apparently.
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psano2
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Is zith a static drug? I'm on that too, but I prefer the idea of bein on bactericidal drugs.
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cottonbrain
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i thought it was bacteriostatic -- can somebody help?

here's a definition i found:

azithromycin (zithrōmīsin),
n brand name: Zithromax;
drug class: macrolide antibiotic;

action: binds to 50S ribosomal subunits of susceptible bacteria and suppresses protein synthesis; similar spectrum of activity to erythromycin;

uses: infections of the upper and lower respiratory tract, uncomplicated skin infections.

Mosby's Dental Dictionary, 2nd edition. 2008 Elsevier, Inc

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B R H
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Azithromycin & minocycline are both bacteriostatic antibiotics. They will slow or stop the bacterial reproduction so your immune system can kill them, assuming it is healthy enough to do so. Bacteriostatic antibiotics DO NOT directly kill the bacteria.

Looks like your doctor has taken some interest in the Marshall Protocol or at least is familiar with Marshall's work.

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CraigC
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I thought I read in Dr. B's literature, that while Doxy and others are bacteriostatic in lower doses, higher doses induce kill kinetics. Wouldn't this mean that they do kill the spirochete in higher, sustained doses?

[ 16. April 2008, 12:19 PM: Message edited by: CraigC ]

--------------------
Craig

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cottonbrain
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I just met with my LLMD yesterday, and he was very happy about my five-six weeks of herxing on the bacterostatics; he thought that was a very good sign that things are working.

he just added to my protocol:

bactrim 2x day (for positive bart test results)
cholestyramine 2x/day for detox

Thanks, all, for your feedback! So far the statics with benicar seem to be doing a good job.

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