Marnie
Frequent Contributor (5K+ posts)
Member # 773
posted
Those of you who are using MMS to oxidize iron and manganese, IMO, had better watch your copper levels and be very aware that MMS looks to trigger coagulation which is already a problem in lyme.
This is what might be happening...
Chlorine dioxide...
"It destroys THM precursors and ***increases coagulation***"
Coagulation Factor V contains copper ion.
Coagulation factor V is a cofactor that participates with factor Xa to activate prothrombin to thrombin.
The Rx (abx.) which might get you out of copper trouble is Dpen.
While some copper is good (copper bracelets for arthritis were once the "rage"), too much copper isn't good.
I think far infrared to trigger HO-1 (which is downregulated by the activated gene, HIF-1) maybe safer...slower, but safer.
I know...you are oxidizing Mn too...I don't know if that is a good thing.
And heme oxygenase-1 (HO-1) has been identified as an inducer of manganese superoxide dismutase (MnSOD).
"Our group has shown both in vitro and in vivo that both
***tumor growth and vascularization are
suppressed with increased MnSOD***.
We hypothesize that the SOD enzymes and HIF-l are linked and that SOD overexpression in malignant tumors can modulate HIF-l alpha protein levels.
To test this hypothesis we exposed MnSOD overexpressing cells to hypoxia and examined HIF-l alpha protein. Our results demonstrated that increase of MnSOD (3-30 fold activity) in breast cancer cells suppressed the accumulation of HIF-l alpha protein under hypoxia in a dose dependent manner.
These results suggest that MnSOD regulates HIP-l alpha and that the modulation of HIP-l alpha protein levels may account for the tumor suppressor function of SOD enzyme."
"Many breast cancer cells typically exhibit ***lower expression of manganese superoxide dismutase (MnSOD)*** compared to the normal cells from which they arise. This decrease can often be attributed to a defect in the transcription of SOD2, the gene encoding MnSOD;"
For those who are reading and wondering why people are using MMS to oxidize iron and Mn...
Re: iron and Bb:
***"We have identified an outer membrane protein (28 kDa) from B. burgdorferi B31 that
bound holo-Tf but not apo-Tf." ***
transferrin (Tf)
"Iron-loaded (holo)-transferrin (Tf)
iron-depleted (apo-) Tf "
So Bb has a protein that binds to iron loaded transferrin.
And HO-1 liberates bound iron.
"Thus, cytoprotection by HO1 is attributable to its augmentation of ***iron efflux*** reflecting a role for HO1 in modulating intracellular iron levels and regulating cell viability."
"However, the combination of holo-Tf with thrombin (but NOT apo-Tf with thrombin) caused brain edema, DNA damage, and intracellular iron accumulation in the ipsilateral basal ganglia. "
Bb uses iron another way too:
"Infective and noninfective strains of Borrelia burgdorferi, along with Borrelia afzelii and Borrelia garinii,
possessed a single iron-containing superoxide dismutase (SOD)."
[ 11. November 2008, 11:27 AM: Message edited by: Marnie ]
Posts: 9481 | From Sunshine State | Registered: Mar 2001
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lymie_in_md
Frequent Contributor (1K+ posts)
Member # 14197
posted
I don't think the MMS is as bad as all that. It should be determined whether or not it is safe no different then a probiotic. If you take MMS it might be good idea to take added vitamin C, of course away from MMS and keeping track of other minerals.
Too much copper is also a sign your body is retaining copper due fungi and yeasts.
-------------------- Bob Posts: 2150 | From Maryland | Registered: Dec 2007
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