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Author Topic: research on LEDs
jamieL
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I'm starting a thread to keep track of info on photon therapy.

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Diagnosed with :yme and mycoplasma pneumonia Aug 08.
Treating with Doxy and Ceftin ever since. 15 sessions in hyperbaric o2 chamber

Posts: 183 | From all around | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
jamieL
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Member # 16563

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http://www.liebertonline.com/doi/abs/10.1089/pho.2006.24.680


Photomedicine and Laser Surgery
Effects of Combined 405-nm and 880-nm Light on Staphylococcus aureus and Pseudomonas aeruginosa in Vitro

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To cite this paper:
J. Stephen Guffey, Jay Wilborn. Photomedicine and Laser Surgery. December 1, 2006, 24(6): 680-683. doi:10.1089/pho.2006.24.680.

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Full Text PDF: * HiRes for printing (59.1 KB) * PDF Plus w/ links (72.8 KB)


Dr. J. Stephen Guffey, Ed.D.
Physical Therapy Plus, Bauxite, Arkansas.
Jay Wilborn, M.Ed.
National Park Community College, Hot Springs, Arkansas.
Objective: The aim of this study was to determine the effect of a combination of 405-nm blue light and 880-nm infrared light on Staphylococcus aureus and Pseudomonas aeruginosa in vitro. Background Data: Reports indicate that certain wavelengths and treatment parameters of light promote the growth of bacteria, but our earlier study indicates that light at specific wavelengths and intensities are bactericidal for specific organisms (1). Methods: Two common aerobes, Staphylococcus aureus and Pseudomonas aeruginosa were tested because of their frequent isolation from skin infections and wounds. Each organism was treated simultaneously with a combination of 405-nm and 880-nm light emitted by a cluster of Super Luminous Diodes (SLDs). Doses of 1, 3, 5, 10, and 20 Jcm2 were used. Colony counts were performed and compared to untreated controls using Student t tests and one-way ANOVA with Tukey and Scheffe post hoc analyses. Results: The results revealed significant dose-dependent bactericidal effects of the combined blue and infrared light on Staphylococcus aureus (F 4,94 = 5.38, p = 0.001) and Pseudomonas aeruginosa (F 4,95 = 21.35, p < 0.001). With P. aeruginosa, the treatment reduced the number of bacteria colonies at all doses, achieving statistical significance at 1, 3, and 20 J cm2 doses and reducing bacterial colony by as much as 93.8%; the most effective dose being 20 J cm2. Irradiation of S. aureus resulted in statistically significant decreases in bacterial colonies at all dose levels; the most decrease, 72%, was also achieved with 20 Jcm2.

Conclusion: Appropriate doses of combined 405-nm and 880-nm phototherapy can kill Staphylococcus aureus and Pseudomonas aeruginosa in vitro, suggesting that a similar effect may be produced in clinical cases of bacterial infection.

--------------------
Diagnosed with :yme and mycoplasma pneumonia Aug 08.
Treating with Doxy and Ceftin ever since. 15 sessions in hyperbaric o2 chamber

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jamieL
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http://www.wired.com/medtech/health/news/2003/10/60786?currentPage=2

--------------------
Diagnosed with :yme and mycoplasma pneumonia Aug 08.
Treating with Doxy and Ceftin ever since. 15 sessions in hyperbaric o2 chamber

Posts: 183 | From all around | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
jamieL
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Photonic Stimulation (Photobiomodulation) - Clinical and Experimental Applications of NIR-LED


KRISTINA D. DESMET, B.S.,1 DAVID A. PAZ, B.S.,2 JESSE J. CORRY, M.D.,2 JANIS T. EELLS, Ph.D.,1 MARGARET T.T. WONG-RILEY, Ph.D.,3 MICHELE M. HENRY, B.S.,4 ELLEN V. BUCHMANN, B.S.,2 MARY P. CONNELLY, B.S.,2 JULIAV. DOVI, Ph.D.,2 HUAN LING LIANG, M.D.,3 DIANE S. HENSHEL, Ph.D.,5 RONNIE L. YEAGER, M.S.,5 DEBORAH S. MILLSAP, M.S.,5 JINHWAN LIM, M.S.,5 LISA J. GOULD, M.D., Ph.D.,6RINA DAS, Ph.D.,7 MARTI JETT, Ph.D.,7 BRIAN D. HODGSON, D.D.S.,8 DAVID MARGOLIS, M.D.,9 and HARRY T. WHELAN, M.D.2


ABSTRACT:This review presents current research on the use of far-red to near-infrared (NIR) light treatment in various in vitro and in vivo models.

Low-intensity light therapy, commonly referred to as ``photobiomodulation,'' also called "photonic stimulation," uses light in the far-red to near-infrared region of the spectrum (630-1000 nm) and modulates numerous cellular functions.

Positive effects of NIR-light-emitting diode (LED) light treatment include acceleration of wound healing, improved recovery from ischemic injury of the heart, and attenuated degeneration of injured optic nerves by improving mitochondrial energy metabolism and production.

Various in vitro and in vivo models of mitochondrial dysfunction were treated with a variety of wavelengths of NIR-LED light. These studies were performed to determine the effect of NIR-LED light treatment on physiologic and pathologic processes.

NIR-LED light treatment stimulates the photoacceptor cytochrome c oxidase, resulting in increased energy metabolism and reduction. NIR-LED light treatment accelerates wound healing in ischemic rat and murine diabetic wound healing models, attenuates the retinotoxic effects of methanol-derived formic acid in rat models, and attenuates the developmental toxicity of dioxin in chicken embryos.

Furthermore, NIR-LED light treatment prevents the development of oral mucositis in pediatric bone marrow transplant patients. The experimental results demonstrate that NIR-LED light treatment stimulates mitochondrial oxidative metabolism in vitro, and accelerates cell and tissue repair in vivo.

NIR-LED light represents a novel, noninvasive, therapeutic intervention for the treatment of numerous diseases linked to mitochondrial dysfunction.


CONCLUSION:
Experimental results demonstrate that NIR-LED light treatmentstimulates mitochondrial oxidative metabolism in vitro,and accelerates cell and tissue repair in vivo. NIR-LED lightrepresents a noninvasive, therapeutic intervention forthe treatment of numerous diseases linked to mitochondrialdysfunction, including age-related macular degeneration,Leber's hereditary optic neuropathy, and Parkinson's and Alzheimer'sdisease.

--------------------
Diagnosed with :yme and mycoplasma pneumonia Aug 08.
Treating with Doxy and Ceftin ever since. 15 sessions in hyperbaric o2 chamber

Posts: 183 | From all around | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
jamieL
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http://www.springerlink.com/content/g531t6r776l86462/

Chukuka S. Enwemeka2 , Deborah Williams2, Steve Hollosi3 and David Yens3

(2) School of Health Professions, Behavioral & Life Sciences, New York Institute of Technology, Old Westbury, NY, USA
(3) New York College of Osteopathic Medicine, New York Institute of Technology, Old Westbury, NY, USA

Abstract
Methicillin resistant Staphylococcus aureus (MRSA) is a virulent form of staphylococcus easily spread and to control. When contracted it can be exceedingly difficult to control especially where healthcare is not readily available. Blue light at wavelengths above 400 nm and doses near 60 J/cm2 are shown to be effective at controlling infections.
Keywords MRSA - blue light


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Chukuka S. Enwemeka
Email: [email protected]

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--------------------
Diagnosed with :yme and mycoplasma pneumonia Aug 08.
Treating with Doxy and Ceftin ever since. 15 sessions in hyperbaric o2 chamber

Posts: 183 | From all around | Registered: Jul 2008  |  IP: Logged | Report this post to a Moderator
psano2
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Thanks for doing this.
Posts: 975 | From California | Registered: Apr 2007  |  IP: Logged | Report this post to a Moderator
sixgoofykids
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http://www.cuph.org/projects/global/material/546/binary/

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sixgoofykids.blogspot.com

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