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» LymeNet Flash » Questions and Discussion » Medical Questions » WB Band 66

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Author Topic: WB Band 66
6t5frlane
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MY friend got a Lab Corp WB back ( yeah I know ) showed present on IGG for bands 66 and 41. On the IGM only 23. His DR says it's Neg. My interest is the 66 band? Can you help out there. I read DR C's list
Posts: 355 | From NY | Registered: Jan 2006  |  IP: Logged | Report this post to a Moderator
TerryK
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http://www.canlyme.com/wb.html
Written by Carl Brenner

"For example, many patients with Lyme disease will show reactive bands at, say, 60 and/or 66 kDa. However, these correspond to common proteins in many bacteria, not just Borrelia burgdorferi, and so are of limited diagnostic usefulness, especially in the absence of other, more species-specific bands."

"The band at 41 kDa corresponds to Bb's flagella (the whip like organelles used for locomotion -- Bb has several) and is one of the earliest to show up on the Western blots of Lyme disease patients. But for some reason it is also the most commonly appearing band in control subjects. This may be due to the fact that many people are exposed to spirochetes at some time in their lives and so their sera might cross react with this protein."

Terry

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6t5frlane
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Thanks Terry
Posts: 355 | From NY | Registered: Jan 2006  |  IP: Logged | Report this post to a Moderator
   

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