LymeNet Home LymeNet Home Page LymeNet Flash Discussion LymeNet Support Group Database LymeNet Literature Library LymeNet Legal Resources LymeNet Medical & Scientific Abstract Database LymeNet Newsletter Home Page LymeNet Recommended Books LymeNet Tick Pictures Search The LymeNet Site LymeNet Links LymeNet Frequently Asked Questions About The Lyme Disease Network LymeNet Menu

LymeNet on Facebook

LymeNet on Twitter




The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

LymeNet Flash Discussion
Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive


The Lyme Disease Network is a non-profit organization funded by individual donations.

LymeNet Flash Post New Topic  New Poll  Post A Reply
my profile | directory login | register | search | faq | forum home

  next oldest topic   next newest topic
» LymeNet Flash » Questions and Discussion » Medical Questions » plaquenil...low platelets, reduced liver function

 - UBBFriend: Email this page to someone!    
Author Topic: plaquenil...low platelets, reduced liver function
lisamlj
Member
Member # 24666

Icon 1 posted      Profile for lisamlj     Send New Private Message       Edit/Delete Post   Reply With Quote 
went to llmd today and she pulled me off all meds. It seems that plaquenil is causing problems with liver function (liver panel 2 months ago was normal) now the numbers are slightly elevated...don't remember them specifically. Also platelet count was a tad low. She pulled me off all meds (plaqeunil/ flagyl(pulse every third week)/ doxy/ biaxin.

I'll be off for two weeks then retest liver function/ platelet count and decide where to go from there. I've been doing this tx for 3 monthes now and have made significant strides in my recovery.

What can I expect as a result of being pulled off all meds for 2-3 weeks? Currently, I do 3 weeks on meds followed by one week off. I'm worried about losing ground after the progress I have made.

--------------------
bitten: ?
diagnosed: 2/25/10
started tx: 3/1/10

Posts: 26 | From Raleigh/Durham NC | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
karenl
Frequent Contributor (1K+ posts)
Member # 17753

Icon 1 posted      Profile for karenl     Send New Private Message       Edit/Delete Post   Reply With Quote 
Just got my labs and I have the same problem. Platelets are low, liver function borderline.
I was just doing a bit better on mincyclin and do not want to stop treatment.

Does she think the low platelets are from plaquenil?

Posts: 1834 | From US | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
lisamlj
Member
Member # 24666

Icon 1 posted      Profile for lisamlj     Send New Private Message       Edit/Delete Post   Reply With Quote 
Karen-
yes, she does think that the low platelets are from plaquenil. I don't want to stop treatment either. I am trying to look at this as a minor bump in the rode and not a major set back. Good Luck, Karen. Keep me posted on when you resume tx.

--------------------
bitten: ?
diagnosed: 2/25/10
started tx: 3/1/10

Posts: 26 | From Raleigh/Durham NC | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
karenl
Frequent Contributor (1K+ posts)
Member # 17753

Icon 1 posted      Profile for karenl     Send New Private Message       Edit/Delete Post   Reply With Quote 
there are some herbs recommended, will post if you are interested.
Posts: 1834 | From US | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
lisamlj
Member
Member # 24666

Icon 1 posted      Profile for lisamlj     Send New Private Message       Edit/Delete Post   Reply With Quote 
Right now I take milk thistle (silymarin)-600 mg, selenium-175 mcg, vit c (as ascorbic acid)-300mg and green tea. Are there others that have helped you?

--------------------
bitten: ?
diagnosed: 2/25/10
started tx: 3/1/10

Posts: 26 | From Raleigh/Durham NC | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
lightfoot
Frequent Contributor (5K+ posts)
Member # 2536

Icon 1 posted      Profile for lightfoot     Send New Private Message       Edit/Delete Post   Reply With Quote 
Plaquenil may be the culprit for me too. I was very surprised because I have been taking it with success for about 6 years along with Zith. I'm having the same effect.....low platelets, low WBC and elevated liver enzymes....I would be very interested in input on natural remedies.

--------------------
Healing Smiles.....lightfoot [Smile] [Smile] [Smile]

Posts: 6901 | From CO | Registered: May 2002  |  IP: Logged | Report this post to a Moderator
karenl
Frequent Contributor (1K+ posts)
Member # 17753

Icon 1 posted      Profile for karenl     Send New Private Message       Edit/Delete Post   Reply With Quote 
Millefolium C 30 helps with bleeding
Papaya juice
wheat grass juice
aloe vera gel.
Hope I do not get a herx from these.Just got them.

These should help to restore platelets. I also found that platelets need protein and I am low in protein.

Posts: 1834 | From US | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
mam
Member
Member # 22695

Icon 1 posted      Profile for mam     Send New Private Message       Edit/Delete Post   Reply With Quote 
Medications are not the only things that can impact platelets. You should know that green tea can lower platelet level as can omega oil. These are only a few supplements that can add to the platelet problem. See link for more complete information:

http://www.pdsa.org/about-itp/warnings.html

Posts: 28 | From ri | Registered: Oct 2009  |  IP: Logged | Report this post to a Moderator
karenl
Frequent Contributor (1K+ posts)
Member # 17753

Icon 1 posted      Profile for karenl     Send New Private Message       Edit/Delete Post   Reply With Quote 
Thanks, this is important.
Unfortunately I have also my beta2glycoprotein elevated what looks more like I have a bone marrow problem or a very extreme inflammation.
Lightfoot, did you have this tested as well?

Posts: 1834 | From US | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
FunkOdyssey
LymeNet Contributor
Member # 15855

Icon 1 posted      Profile for FunkOdyssey     Send New Private Message       Edit/Delete Post   Reply With Quote 
Elevated beta 2 glycoprotein is associated with antiphospholipid syndrome which is an autoimmune clotting disorder and often a subset of Lupus. Might be a consequence of Lyme. Nothing to do with your bone marrow though.
Posts: 195 | From Manchester, CT | Registered: Jun 2008  |  IP: Logged | Report this post to a Moderator
karenl
Frequent Contributor (1K+ posts)
Member # 17753

Icon 1 posted      Profile for karenl     Send New Private Message       Edit/Delete Post   Reply With Quote 
FunkOdyssey,

do you know more about this? According to google it is a marker for bone cancer and for lymphoma.
I have bone and lymph problems. But I just started abx treatment and feel better, so I think it might be a die off thing, like too many cells dead and the glycoprotein now opens in the bloodstream.
I just hope it is lyme-lupus related.I want my doctor since years to check the antiphospholipid antibodies, but he thinks I do not have it.

The papaya juice is powerful!!

Posts: 1834 | From US | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
lisamlj
Member
Member # 24666

Icon 1 posted      Profile for lisamlj     Send New Private Message       Edit/Delete Post   Reply With Quote 
mam-

thank you for the link

--------------------
bitten: ?
diagnosed: 2/25/10
started tx: 3/1/10

Posts: 26 | From Raleigh/Durham NC | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
FunkOdyssey
LymeNet Contributor
Member # 15855

Icon 1 posted      Profile for FunkOdyssey     Send New Private Message       Edit/Delete Post   Reply With Quote 
quote:
Originally posted by karenl:
FunkOdyssey,

do you know more about this? According to google it is a marker for bone cancer and for lymphoma.
I have bone and lymph problems. But I just started abx treatment and feel better, so I think it might be a die off thing, like too many cells dead and the glycoprotein now opens in the bloodstream.
I just hope it is lyme-lupus related.I want my doctor since years to check the antiphospholipid antibodies, but he thinks I do not have it.

The papaya juice is powerful!!

http://www.specialtylabs.com/books/display.asp?id=1066
Posts: 195 | From Manchester, CT | Registered: Jun 2008  |  IP: Logged | Report this post to a Moderator
Wolfed Out
LymeNet Contributor
Member # 23727

Icon 1 posted      Profile for Wolfed Out     Send New Private Message       Edit/Delete Post   Reply With Quote 
Lisa,

You could look into the Cowden protocol as well, to use temporarily.

Many people have stated that Cowden will stop most people from getting worse, so it sounds like a good time to give yourself a "band-aid" at the very least with some herb treatments.

Some suggestions would be Cumanda, Enula and Samento. There are others. Please research the Cowden Protocol.

Posts: 829 | From MD | Registered: Dec 2009  |  IP: Logged | Report this post to a Moderator
karenl
Frequent Contributor (1K+ posts)
Member # 17753

Icon 1 posted      Profile for karenl     Send New Private Message       Edit/Delete Post   Reply With Quote 
Funk,

thank you for this great link.I did more research and found a lupus doctor who treats with antibiotics. Will ask for his advice tomorrow.Also PAD (peripheral artery disease and deep vein thrombosis)is linked to this marker.
In the end it is bad infection and debris blocking our system.

Posts: 1834 | From US | Registered: Oct 2008  |  IP: Logged | Report this post to a Moderator
   

Quick Reply
Message:

HTML is not enabled.
UBB Code is enabled.

Instant Graemlins
   


Post New Topic  New Poll  Post A Reply Close Topic   Feature Topic   Move Topic   Delete Topic next oldest topic   next newest topic
 - Printer-friendly view of this topic
Hop To:


Contact Us | LymeNet home page | Privacy Statement

Powered by UBB.classic™ 6.7.3


The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA


| Flash Discussion | Support Groups | On-Line Library
Legal Resources | Medical Abstracts | Newsletter | Books
Pictures | Site Search | Links | Help/Questions
About LymeNet | Contact Us

© 1993-2020 The Lyme Disease Network of New Jersey, Inc.
All Rights Reserved.
Use of the LymeNet Site is subject to Terms and Conditions.