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» LymeNet Flash » Questions and Discussion » Medical Questions » What is Plaquenil...exactly?

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Author Topic: What is Plaquenil...exactly?
triathletelymie
LymeNet Contributor
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I have read different things...what is Plaquenil, exactly...an anti-malarial, I know...but... is it also an anti-parasitic and/or an antibiotic?

--------------------
? date of bite/no rash
10/09 symptoms, 4/10 diagnosed, after 6 mos. ER visits, tons of docs/tests
CDC+ 23/39/41/45/58/66/93
currently on oral plaquenil, doryx, rifampin, pyrazinamide, nystatin, numerous supplements

Posts: 718 | From Pennsylvania | Registered: Jun 2010  |  IP: Logged | Report this post to a Moderator
EyeBob
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Count it as an "anti-infective." It's a better way to describe it's action. It's also postulated to affect the inflammatory process which is probably why it's beneficial for RA, SLE and others. In Lyme, my understanding is that it augments the environment in cells that Bb may be hiding. It either makes the environment less inviting for them and/or facilitates the clarithromycin (Biaxin) to work better against the Bb.

Below are two links to look at if you're really interested or obsessed or bored..or all 3.

http://www.rxlist.com/plaquenil-drug.htm

and

http://en.wikipedia.org/wiki/Plaquenil

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Amanda
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What eyeBob said plus

its a "quinine" drug. So its in the same drug class as Larium and other anti malarials.

IT supposed to help raise the pH inside your cells, which helps some abx penetrate better (lyme thrives in and creates a low pH environemnt)

--------------------
"few things are harder to put up with than the annoyance of a good example" - Mark Twain

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triathletelymie
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Thanks EyeBob and Amanda. And...EyeBob...I am all three! [Smile]

--------------------
? date of bite/no rash
10/09 symptoms, 4/10 diagnosed, after 6 mos. ER visits, tons of docs/tests
CDC+ 23/39/41/45/58/66/93
currently on oral plaquenil, doryx, rifampin, pyrazinamide, nystatin, numerous supplements

Posts: 718 | From Pennsylvania | Registered: Jun 2010  |  IP: Logged | Report this post to a Moderator
BackinStOlaf
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My doc said they stopped using plaquenil because they didn't notice it worked any better for their patients than NOT using it

--------------------
First Symptom 9/09
Multiple docs, negative Labcorp test
LLMD: 1/10
Positive Igenex/CDC test
Treatment 2/10
2/10-8/10 Amox, ceftin, zith, flagyl
Currently: Bicillin, Minocycline, still dealing with severe breathing issues

 -

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cleo
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Plaquenil is in the quinolone family.

http://emedicine.medscape.com/article/1229016-overview

Levaquin is a quinolone family drug.
http://en.wikipedia.org/wiki/Quinolone

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lymeladyinNY
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Hmm, that's interesting, St. Olaf. I felt like plaquenil took me to a different level. I feel better on it than off it.

I told my LLMD I love it and please, keep me on it.

- Lymelady

--------------------
I want to be free

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hurtingramma
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I like plaquenil too. I also have psoriatic arthritis and it helps with that, but mainly it helps my brain function.

I have really bad cog fog when I'm off it, for one reason or another.

--------------------
"Few of us can do great things, but all of us can do small things with great love". Mother Theresa

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rks
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I was told that it's suppose to help with pain as well as babesia.
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bcb1200
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Plaquenil supposedly raises the PH of the cells and makes the BIaxin / Zith work better.

--------------------
Bite date ?
2/10 symptoms began
5/10 dx'd, after 3 months numerous test and doctors

IgM Igenex +/CDC +
+ 23/25, 30, 31, 34, 41, 83/93

Currently on:

Currently at around 80% +/- most days.

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