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» LymeNet Flash » Questions and Discussion » Medical Questions » when take Artemisinin during the day?

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Author Topic: when take Artemisinin during the day?
2roads
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Hey,

We are on Mepron/Zith and Bactrim 2 times a day. The doctor wants Art added.

Want to administer at a high therapeutic threshold time but also want to ease up on the liver etc. I know the half-life for Mep and Zith are long.

Any thoughts?

Thanks loads,

2roads

Posts: 2214 | From West Chester, PA | Registered: Aug 2003  |  IP: Logged | Report this post to a Moderator
Lemon-Lyme
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I'm also curious about this. I just started Art yesterday, and have been taking it at the same time as my Malarone... but no idea when it ideally should be dosed.

I think it's supposedly best taken away from food, but I'm a little afraid of stomach upset. And pulsing it seems to be the way to go, so I plan on trying 400mg/4 days a week/3 days off, split up as two daily 200mg doses.

But again, I am just guessing right now as to the best dose, and when to take.

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2roads
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We are doing the same pulsing, 4 on 3 off. I think the dose sounds about right per the bottle. Splitting it up is good not to overload the body.

But when to administer w/r/to any antibiotics currently on?. Hmmmm.........

Any more thoughts?

Thanks Lemon.

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2roads
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up?! [group hug]
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TF
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My now famous lyme doc had me take art twice a day on an empty stomach.

It didn't bother my stomach at all.

So, take it all by itself.

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Lauralyme
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It's best taken with grapefruit juice...prevents resistance

--------------------
Fall down seven times, get up eight
~Japanese proverb

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Lemon-Lyme
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Unless the person is also taking other drugs that could be affected by grapefruit, which seems like most drugs.

I read one article somewhere (in a cancer forum, I think), that stated absorption was actually increased if fats were taken at the same time, sort of contradicting the empty stomach thing. But I'm not sure how true that is.

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valeriedc
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My lyme doc says to take it 2X per day with the meds continually. I experimented and found that taking it on an empty stomach, which I can not do with the meds, seems to result in a herx. Pulsing seems to be better than continually taking the art.
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TF
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This thread includes a study that shows why art needs to be pulsed:

http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/95879?

Posts: 9931 | From Maryland | Registered: Dec 2007  |  IP: Logged | Report this post to a Moderator
   

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