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» LymeNet Flash » Questions and Discussion » Medical Questions » B12 shots + folate + benzos = extreme tiredness

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Author Topic: B12 shots + folate + benzos = extreme tiredness
kday
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Well, I have been taking this stuff, and for the first time in as long as I can remember, the benzos are sedating me and making me very tired. Extremely tired. Before these supplements, I couldn't take enough benzos to actually sedate me to the point where I feel normal. I felt very overstimulated, always agitated, yet fatigued (in a non-tired sort of way).

I cut back a bit today, but know you aren't supposed to cut back fast. Maybe I can if it is making me this tired. I'll have to visit my psychiatrist. I theoretically been on them long enough to build tolerance to my dose, but now, that doesn't seem the case.

I'm on:

.5mg klonopin x3
5 mg Ativan/day

I think my neuropsychiatric issues might be resolving because of these supplements. I ordered a folate test that I will take tomorrow to see if my folate/folic acid really is extremely low before a lot builds up in my system. If it's low, perhaps I should get prescription folate (such as Deplin). I don't take an anti-depressant.

I'm just wondering if it is the B12 or folate, or a combination. Anybody have extreme neuropsychiatric symptoms go away with these vitamins? Is that possible? Although I don't like the tiredness and being in a drugged state, I hope I don't jinx myself.

Thanks!!

edit: I actually do feel slightly anxious, but I think it's because I feel drugged and I am not used to being in a sedated state. I would compare the feeling to being high on something potent.

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dali
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I don't know about extreme neuropsychiatric symptoms, but vitamin B supplements work wonders for the nervous system/brain. I take a high dose liquid supplement of vitamin B...it helps.
Kday, enjoy your sedated state for now...your body needs rest!
keep on healing-

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kday
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Off to lab today to check folate/folic acid levels.

I find articles linking low B12 and folate to depression, but no so much about anxiety.

Maybe my brain was put on backwards? Or perhaps upside down? That would explain A LOT!

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valeriedc
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My llmd prescribed deplin also. However my insurance doesn't cover it-a $100/month that I have to pay. After some researching my husband found that Solgar has the same formulation as deplin. So I take 9-800mcg of folate per day instead of the deplin. Jury is still out. Hopefully it will work-much, much cheaper.
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Sophie1234
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One of my drs (neuro) tested me for a genetic defect called MTHFR. (Yeah, I know what that looks like, ha ha) Folate needs to go through a four step process to be able to cross the blood brain barrier. If you have this particular genetic defect, the four step process is interupted and it doesn't cross.

I tested postive. I was also rxed a folate drug, but my LLMD told me to get L-methyl folate instead, which is the folate, but already converted to cross the BBB. It was about $28.00.

I don't know if you already know this. I found it really interesting.

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kday
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Yea, I am going to get a MTHFR test next time I see my phsysican. I just ordered the cheap folic acid test myself (since I didn't want to stop supplementation waiting to see Dr.), and if the results come back bad, I will have him order the test (covered by insurance).

That being said I felt terrible today. I took 1200 mg of NAC this morning because I was coming down with a cold going around the house and was stuffed up when I woke. Between elderberry extract, nanosilver, and NAC, I believe I eliminated it, but I felt very anxious.

After a quick google search, a CFS protocol site says don't combine NAC with folate and B12 because you can start feeling very bad and it messes up methylation when you are trying to restore it. Now I know. It would explain why I felt so bad, but maybe the virus was enough to stress my nervous system. I guess I can't know for sure, but no more NAC!

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