LymeNet Home LymeNet Home Page LymeNet Flash Discussion LymeNet Support Group Database LymeNet Literature Library LymeNet Legal Resources LymeNet Medical & Scientific Abstract Database LymeNet Newsletter Home Page LymeNet Recommended Books LymeNet Tick Pictures Search The LymeNet Site LymeNet Links LymeNet Frequently Asked Questions About The Lyme Disease Network LymeNet Menu

LymeNet on Facebook

LymeNet on Twitter




The Lyme Disease Network receives a commission from Amazon.com for each purchase originating from this site.

When purchasing from Amazon.com, please
click here first.

Thank you.

LymeNet Flash Discussion
Dedicated to the Bachmann Family

LymeNet needs your help:
LymeNet 2020 fund drive


The Lyme Disease Network is a non-profit organization funded by individual donations.

LymeNet Flash Post New Topic  New Poll  Post A Reply
my profile | directory login | register | search | faq | forum home

  next oldest topic   next newest topic
» LymeNet Flash » Questions and Discussion » Medical Questions » Can't tolerate full dose of Rifampin/am I wasting my time?

 - UBBFriend: Email this page to someone!    
Author Topic: Can't tolerate full dose of Rifampin/am I wasting my time?
Sophie1234
LymeNet Contributor
Member # 26412

Icon 1 posted      Profile for Sophie1234     Send New Private Message       Edit/Delete Post   Reply With Quote 
I have tried to titrate up on my Rifampin, but cannot seem to tolerate more than 75 mg. Even at 100mg my heart pounds and I have air hunger.

Question: I am in screaming pain, so I think it is doing something. I am currently taking it with Biaxin. Do I continue on the low dose or give it up and try something else for Bartonella?

Posts: 113 | From CA | Registered: Jun 2010  |  IP: Logged | Report this post to a Moderator
Haley
Frequent Contributor (1K+ posts)
Member # 22008

Icon 1 posted      Profile for Haley     Send New Private Message       Edit/Delete Post   Reply With Quote 
Rifampin is a tough one to decipher. It may be side effects of the medicine as some people can't seem to process it in their system.

I had severe problems but I started with 600 mg. I almost went to ER because I felt like I was having a heart attack.

I am considering trying it again just to see if it may have been hitting an infection hard. I do remember that after only two weeks on Rifampin some of my severe symptoms left. A year later they seem to be back.

Sorrry. I'm not much help and can't answer your question but I thought I would share my experience with you.

Posts: 2232 | From USA | Registered: Aug 2009  |  IP: Logged | Report this post to a Moderator
Sophie1234
LymeNet Contributor
Member # 26412

Icon 1 posted      Profile for Sophie1234     Send New Private Message       Edit/Delete Post   Reply With Quote 
Thank you Haley. I have a call in to my dr. and will see what he says. God bless you.
Posts: 113 | From CA | Registered: Jun 2010  |  IP: Logged | Report this post to a Moderator
Pocono Lyme
Frequent Contributor (1K+ posts)
Member # 5939

Icon 1 posted      Profile for Pocono Lyme     Send New Private Message       Edit/Delete Post   Reply With Quote 
Sophie,

Bea Seibert posted an article a while back about Rifampin having a mild effect on Babesia.

I think her husband also couldn't tolerate Very low doses of Rifampin. After treating with Chloroquine and Primaquine he was able to do high dose Rifampin.

Hope this might help you.

--------------------
2 Corinthians 12:9-11


9 But he said to me, �My grace is sufficient for you, for my power is made perfect in weakness.� Therefore I will boast all the more gladly about my weaknesses, so that Christ�s power may rest on me.

Posts: 1445 | From Poconos, PA | Registered: Jul 2004  |  IP: Logged | Report this post to a Moderator
Sophie1234
LymeNet Contributor
Member # 26412

Icon 1 posted      Profile for Sophie1234     Send New Private Message       Edit/Delete Post   Reply With Quote 
That is good to know, Pocono I will look for this post. Thank you!
Posts: 113 | From CA | Registered: Jun 2010  |  IP: Logged | Report this post to a Moderator
NMN
LymeNet Contributor
Member # 11007

Icon 1 posted      Profile for NMN     Send New Private Message       Edit/Delete Post   Reply With Quote 
hi Pocono,

I just wanted to chine in with this link I posted a few days ago which I dont think got much notice.

Rigampin is effective against babesia/malaria parasitic infections. I have been fighting bart for quite a while and it has been causing some nasty eye inflammation the worst being uveitis which of course is sight threatening.

I could not for the life of me work out why when I used high doses of rifampin (i.e 900mg/1200mg) I would get immediate relief from many symptoms and get a huge boost of energy back followed by a worsening 3 days later but overall my eye would settle. I used these doses as this is what is used by opthamologists for chronic bartonella of the eye.

After many rounds I have realised that babs/malaria type co is being immediately suppressed by these rifampin doses and the knock on effect 3 days or so later is the rifampin hitting the inter cell lyme and bart.

In this particular study they used up to 1500mg in single dose which I have used for a few days also. You must have your lyme and bart load down to tolerate these kinds of doses of course.

Having said that I see your post about Beas husband and that does not surprise me as it really depends on the parasite you are fighting. I never herx on babs meds I just get better.

http://flash.lymenet.org/scripts/ultimatebb.cgi/topic/1/97240?

--------------------
Pos BB and Bart(Q & H IGG pos)
Began treat 1 year after start of illness. Diagnosed Feb 2007.

Posts: 648 | From Ireland | Registered: Jan 2007  |  IP: Logged | Report this post to a Moderator
Pinelady
Frequent Contributor (5K+ posts)
Member # 18524

Icon 1 posted      Profile for Pinelady     Send New Private Message       Edit/Delete Post   Reply With Quote 
I agree, you may not have your loads down enough to tolerate yet.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

Posts: 5850 | From Kentucky | Registered: Dec 2008  |  IP: Logged | Report this post to a Moderator
Haley
Frequent Contributor (1K+ posts)
Member # 22008

Icon 1 posted      Profile for Haley     Send New Private Message       Edit/Delete Post   Reply With Quote 
NMN - I did notice your prior post and thought it was very interesting as I am considering doing Rifampin again.

It was really like going through hell when I tried it before. One of the worse parts was that on top of the side effects my sleep meds didn't work so I couldn't sleep. I was a wreck.

How in the heck did you do 900/1200 mg? How did this dose effect you (any side effects)? Were you able to sleep? How long have you been on this protocol?

Posts: 2232 | From USA | Registered: Aug 2009  |  IP: Logged | Report this post to a Moderator
NMN
LymeNet Contributor
Member # 11007

Icon 1 posted      Profile for NMN     Send New Private Message       Edit/Delete Post   Reply With Quote 
Hi Haley,

I have been doing aggressive treatment for bart for 2 years now. In the beginning 300 mg would send me up the walls also.

I have been taking 1200mg for 6 days now and side effects are nothing noticable to be honest. I take 5mg melatonin time release as always for sleep and it works fine. I sleep 8-11 hours a night although dreams are a bit crazy.

I have to admit I do not think I could tolerate such strong bart treatments were it not for the cymbalta I am taking now. Having said that I dont think that would even suppress the bart rages were they to surface strongly.

I have been taking it with 2 or 3 mino a day but I am struggling to keep babesia at bay right now so I have changed Mino for Bactrim DS which is will help keep babs in check and also hit the bart from a different angle. Thankfully no bad herxing anymore. I think my lyme load is well down now.

I am going to go after babs/malaria with a prim & cloro combo soon as it is undermining all bart and lyme treatments while it is present.

I will only do 2 weeks of rifampin at this dose and then I will switch to levaquin for 2 weeks and then back again. I will also start bicillin shots again twice a week to cover lyme.

--------------------
Pos BB and Bart(Q & H IGG pos)
Began treat 1 year after start of illness. Diagnosed Feb 2007.

Posts: 648 | From Ireland | Registered: Jan 2007  |  IP: Logged | Report this post to a Moderator
NMN
LymeNet Contributor
Member # 11007

Icon 1 posted      Profile for NMN     Send New Private Message       Edit/Delete Post   Reply With Quote 
The other reason for switching rifampin in and out is due to studies I have read in which subjects had 50% reduction in blood levels after 2 weeks.

I think our bodies break down all of these meds over time.

--------------------
Pos BB and Bart(Q & H IGG pos)
Began treat 1 year after start of illness. Diagnosed Feb 2007.

Posts: 648 | From Ireland | Registered: Jan 2007  |  IP: Logged | Report this post to a Moderator
FunkOdyssey
LymeNet Contributor
Member # 15855

Icon 1 posted      Profile for FunkOdyssey     Send New Private Message       Edit/Delete Post   Reply With Quote 
NMN- Are you taking that 1200mg rifampin in one daily dose or two divided doses?
Posts: 195 | From Manchester, CT | Registered: Jun 2008  |  IP: Logged | Report this post to a Moderator
   

Quick Reply
Message:

HTML is not enabled.
UBB Code is enabled.

Instant Graemlins
   


Post New Topic  New Poll  Post A Reply Close Topic   Feature Topic   Move Topic   Delete Topic next oldest topic   next newest topic
 - Printer-friendly view of this topic
Hop To:


Contact Us | LymeNet home page | Privacy Statement

Powered by UBB.classic™ 6.7.3


The Lyme Disease Network is a non-profit organization funded by individual donations. If you would like to support the Network and the LymeNet system of Web services, please send your donations to:

The Lyme Disease Network of New Jersey
907 Pebble Creek Court, Pennington, NJ 08534 USA


| Flash Discussion | Support Groups | On-Line Library
Legal Resources | Medical Abstracts | Newsletter | Books
Pictures | Site Search | Links | Help/Questions
About LymeNet | Contact Us

© 1993-2020 The Lyme Disease Network of New Jersey, Inc.
All Rights Reserved.
Use of the LymeNet Site is subject to Terms and Conditions.