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» LymeNet Flash » Questions and Discussion » Medical Questions » IgeneX results

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Author Topic: IgeneX results
kareamber
LymeNet Contributor
Member # 20110

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Hey everyone,
My cousins wife is having many health issues and many symptoms of lyme. She has tested NEG for everything including lyme. I recently convinced her to test through IgeneX and here are the results. I'm not sure what to make of these as they aren't screaming lyme to me. However, I do know that if those IND were +, she'd have a POS test. Of course her dr said she doesn't have lyme and blew it off. I think she needs to do the antibiotic challenge and retest. But I think shes unsure of lyme and am worried she too may blow the idea off. I'm really worried for her.

What do you all make of these results? Thanks.

IGM RESULT Negative
CDC/NYS RESULT Negative

18 kDa. -
22 KDa -
** 23-25 kDa -
28 kDa -
30 kDa -
** 31 kDa +
** 34 kDa -
** 39 kDa -
** 41 kDa IND
45 kDa -
58 kDa ++
66 kDa -
73 kDa -
** 83-93 kDa IND

IGG RESULT NEGATIVE
CDC/NYS RESULT NEGATIVE

18 kDa -
22 kDa -
**23-25 kDa -
28 kDa -
30 kDa -
**31 kDa -
**34 kDa -
**39 kDa +
**41 kDa IND
45 kDa -
58 kDa +
66 kDa -
73 kDa -
**83-93 kDa -

Thanks!

--------------------
IgeneX IGG POS 30+ 31++++ 41++
IGM 30+ 31+++ 34IND 41IND 83-93IND
Quest NEG IGG 30 and 41 only

Posts: 538 | From Everywhere | Registered: Apr 2009  |  IP: Logged | Report this post to a Moderator
METALLlC BLUE
Frequent Contributor (1K+ posts)
Member # 6628

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That's a tricky one actually. I would lean towards treating Lyme Disease if I was a physician working with that test result and a history compatible with the disease. I would likely run other testing too though to see if other tick infections are present.

I would say Lyme Disease is possible based on these results.

--------------------
I am not a physician, so do your own research to confirm any ideas given and then speak with a health care provider you trust.

E-mail: [email protected]

Posts: 4157 | From Western Massachusetts | Registered: Dec 2004  |  IP: Logged | Report this post to a Moderator
METALLlC BLUE
Frequent Contributor (1K+ posts)
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These are the most important ones to look for when judging this type of test:

The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93.

She has a solid 58 on both IgM and IgG
She has a solid 39 on the IgG
She has an IND 41 on the IgM and IgG
She has a solid 31 on the IgM
She has an IND of 83-93 on the IgM

Compare that to the most significant bands and she has 4.

Think about that now. If we consider cross over reaction, IND's as both negative and or Positive, the final result is still Lyme Disease is likely to be present.

So yeah, Lyme Disease treatment should begin as well as the other testing.

--------------------
I am not a physician, so do your own research to confirm any ideas given and then speak with a health care provider you trust.

E-mail: [email protected]

Posts: 4157 | From Western Massachusetts | Registered: Dec 2004  |  IP: Logged | Report this post to a Moderator
Lymetoo
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Member # 743

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I agree with Mike. What else can show a weak positive on the 83-93 but Lyme? It is the DNA of the Bb. You can't argue with DNA.

The other bands are also significant... esp Band 39.. which, according to Dr C of MO, is "the most specific band of all."

Dr C's Western Blot explanation:
http://tinyurl.com/ffn3x

When to Suspect Lyme Disease
http://tinyurl.com/lx2pz

More info:
http://www.ILADS.org/

Quick Links to Popular topics:

http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/88555

--------------------
--Lymetutu--
Opinions, not medical advice!

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Pinelady
Frequent Contributor (5K+ posts)
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Agree. I would definitely treat.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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kareamber
LymeNet Contributor
Member # 20110

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Thanks everyone. She is going to call Dr. Harris at IgeneX to get his take on it.

I appreciate all the feedback.

--------------------
IgeneX IGG POS 30+ 31++++ 41++
IGM 30+ 31+++ 34IND 41IND 83-93IND
Quest NEG IGG 30 and 41 only

Posts: 538 | From Everywhere | Registered: Apr 2009  |  IP: Logged | Report this post to a Moderator
   

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