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Author
Topic: 27 Reasons why someone could have a false negative Lyme test
steve1906
Frequent Contributor (1K+ posts)
Member # 16206
posted 12-09-2013 09:42 AM
27 Reasons why someone could have a false negative Lyme test www.mentalhealthandillness.com 1. Recent infection before immune response 2. Antibodies are in immune complexes 3. Spirochete encapsulated by host tissue (i.e.: lymphocytic cell walls) 4. Spirochete is deep in host tissue (i.e.: fibroblasts, neurons, etc.) 5. Blebs in body fluid, no whole organisms needed for PCR 6. No spirochetes in body fluid on day of test 7. Genetic heterogeneity (300 strains, 100 in U.S.) 8. Antigenic variability 9. Surface antigens change with temperature 10. Utilization of host protease instead of microbial protease 11. Spirochete in dormancy phase (L-form) with no cell walls 12. Recent antibiotic treatment 13. Recent anti-inflammatory treatment 14. Concomitant infection with Babesia may cause immunosuppression 15. Other causes of immunosuppression 16. Lab with poor technical capability for Lyme disease 17. Lab tests not standardized for late stage disease 18. Lab tests labeled "for investigational use only" 19. CDC criteria is epidemiological not a diagnostic criteria 20. Lack of standardized control 21. Most controls use only a few strains as reference point 22. Few organisms are sometimes present 23. Encapsulated by glycoprotein "S-layer" which impairs immune recognition 24. "S"- layer binds to IgM 25. Immune deficiency 26. Possible down regulation of immune system by cytokines 27. Revised W.B. criteria fails to include most significantOpen this site> http://www.lymeinducedautism.com/images/LIATesting_handout_FINAL.pdf -------------------- Everything I say is just my opinion!
Posts: 3529 | From Massachusetts Boston Area | Registered: Jul 2008
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Lymetoo
Moderator
Member # 743
posted 12-09-2013 03:45 PM
Thanks, Steve! I'll make sure this is found in our Important Links thread in Medical. I used to have it saved in my links, but don't have access to them now. -------------------- --Lymetutu-- Opinions, not medical advice!
Posts: 96237 | From Texas | Registered: Feb 2001
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