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» LymeNet Flash » Questions and Discussion » Activism » An Article we can use. Long term combo antibiotics for ReA

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Author Topic: An Article we can use. Long term combo antibiotics for ReA
Pinelady
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http://www.physorg.com/news191738692.html
In the latest double-blind, placebo-controlled multicenter trial, 42 patients were randomly assigned to one of three treatment groups --

rifampin plus doxycycline, rifampin plus azithromycin, or placebo.

All the patients tested positive for Chlamydia trachomatis or Chlamydia pneumoniae.


They received combination antibiotics or placebo for six months and were followed for three months post-treatment.


Patients treated with the combination antibiotics improved significantly more in measures of the swelling and tenderness of joints and symptom assessment.

In fact, the researchers report, 22 percent of patients receiving combination antibiotics experienced complete remission of ReA, while none in the placebo group did. Significantly more patients receiving combination antibiotics tested negative for Chlamydia bacteria in their blood or joint tissue following treatment.

Adverse side effects, mostly gastrointestinal, were mild.

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Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

Posts: 5850 | From Kentucky | Registered: Dec 2008  |  IP: Logged | Report this post to a Moderator
hshbmom
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Thank you Pinelady.
Posts: 1672 | From AL/WV/OH | Registered: Jun 2006  |  IP: Logged | Report this post to a Moderator
Pinelady
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You are most welcome. I hope we can see all the articles we can find for treating anything for over 4 weeks.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

Posts: 5850 | From Kentucky | Registered: Dec 2008  |  IP: Logged | Report this post to a Moderator
lymie tony z
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Thanks P/L,

The curious aspect of this study makes me ponder even more the effects I get whenever I

get on a singular or even say an IV of Ceftriaxone or an IM of Penicillin"G"

with
metronidazole with either....the lung problems that come out and are only resolved when I have

been put on levaquin and or self deduced that I needed Rifampin(for lung issues plus added

benefit of treating any lyme related "wigglies"

(I've forgotten which one is suseptable to rifampin)?

seemingly hiding out in my lungs durring above treatment regimens....

makes me want to go HMMMMM??

Anyone else ever have issues like I've posted above in this thread???

Or reasons why I might consistantly have these same issues???

I would really like to know what a connection, if any has been either (just) noticed by any lymies.....

OR

Any written literature by any of their LLMD's or whoever...??
zman

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I am not a doctor...opinions expressed are from personal experiences only and should never be viewed as coming from a healthcare provider. zman

Posts: 2527 | From safety harbor florida(origin Cleve., Ohio | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
Pinelady
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zman I suspect we may all throw in the kitchen sick with Lyme. But I understand what symptoms you refer to. Maybe Babs or TB. No one really knows.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

Posts: 5850 | From Kentucky | Registered: Dec 2008  |  IP: Logged | Report this post to a Moderator
lymie tony z
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P/L
I highly doubt TB however I'm pretty sure of Babs.

My own diagnosis due to the symptoms I've retained even after all kinds of different abx's.

One of the main reasons I asked for and got Rifampin last year around this time.

I asked for it again however I was in the medigap and could'nt afford it...


I can now but I'll have to see my PPO later this month to ask for some other abx for Babs.

Any suggestions?
zman

--------------------
I am not a doctor...opinions expressed are from personal experiences only and should never be viewed as coming from a healthcare provider. zman

Posts: 2527 | From safety harbor florida(origin Cleve., Ohio | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
Amanda
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riphampin is potentially effective agasint Lyme, Bartonlella and Erhlichia. This is according to Dr. B's guidelines, I don't know of any studies though that state this.

Drugs for Babs are
Mepron/azithryomyacin - OUTRAGIOUSLY expensive, but if insurance pays, give it a try. For a few, this doesn't work, so

Larium is about 100 a month if insurance doesn'ta pay, Costco has best price on it.

There is also Bactrim combines with flagyl. Not alwasy effective, but cheap

Clyndimyacin plus primaquine, cheap, and a few LLMDs are finding this combo can work when others don't.

Bottom line is that Babs is tough one to beat, and its hard to know what will work unless you just try different combos until you find what works.

Mepron/zith is considered the "gold" standard, but at a cost of 2,500 a month, its out of reach for many people, assuming insurance won't pay. And there are some people finding this protocol supresses, but doens't get rid of, the Babs

EVEN IF YOU HAVE INSURANCE, you can still get assistance, always try at least.

Go to Bridges to Access for free Mepron, Augmentin, Ceftin. Go through the list of their medicines. You must not have insurance, and you have to meet eligibility requirements, you can read about that on the website.

http://www.bridgestoaccess.com/about/program_description.html


The Partnership for Prescription Assistance offers a single point of access to more than 475 public and private patient assistance programs, including more than 180 programs offered by pharmaceutical companies
https://www.pparx.org/Intro.php

There is also
http://www.myfreemedicine.com/

and

www.needymeds.org


http://www.prescriptionhope.com/

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"few things are harder to put up with than the annoyance of a good example" - Mark Twain

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lymie tony z
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Thanks Amanda,
I have tried the Mepron and Ketek....for some reason the insurers at the time would only allow a small script for azithromycin...

I retained the symptoms of the babs...I also noticed the vertical welts on my abdomen that may be related to BARTONELLA "LIKE" Co infection.

The Bartonella should have been dealt with by other ABX's I've used in the past....except for the discovery that it isn't exactly Bartonella anylonger...but only seems like the "OLD" "Cat Scratch Fever Infectious Pathogen" Perhaps Mutated form of the old beastie!

I'm going to ask present doc for the atovoquone and something else this week...or I'll have to wait for my next visit to PA and my LLMD.

Or
This new PPO says he has no problem "REFERRING" me to the "Chronically ill" clinics in Rhode Island.....

Any word on those around here???
zman

--------------------
I am not a doctor...opinions expressed are from personal experiences only and should never be viewed as coming from a healthcare provider. zman

Posts: 2527 | From safety harbor florida(origin Cleve., Ohio | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
   

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