posted
Last night I made a tea out of neem leaves - pretty bitter stuff.
I feel extra fatigued today. Has anybody tried neem? Does it have any effect on spirochetes or parasites?
Posts: 29 | From NY | Registered: Sep 2007
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CaliforniaLyme
Frequent Contributor (5K+ posts)
Member # 7136
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SHOULD work against Babesiosis to some degree!!! *************************************************
1:Ann Trop Med Parasitol. 2006 Jan;100(1):17-22.
Fractions of an antimalarial neem-leaf extract have activities superior to chloroquine, and are gametocytocidal.
Udeinya IJ, Brown N, Shu EN, Udeinya FI, Quakeyie I. Department of Pharmacology, Howard University College of Medicine, Washington, DC 20059, USA.
The antimalarial activities of two fractions (IRDN-A and IRDN-B) of an extract from the leaves of the neem tree (Azadirachta indica) were compared with those of chloroquine, in in-vitro assays against Plasmodium falciparum.
The asexual stages of a chloroquine-sensitive clone (ITG2F6) and a chloroquine-resistant isolate (W2) and the gametocytes of the NF 54 (BD-7) isolate of P. falciparum were used as the drug targets.
Activity against the asexual stages was generally evaluated as the concentrations inhibiting the parasitaemias recorded in the control cultures, after an incubation of 48-72 h, by 50% (IC50) or 100% (IC100).
For the ITG2F6 strain, the IC50 and IC100 (in microg/ml) were, respectively, 10(-5) and 10(-4) for IRDN-A, 10(-3) and 10(-2) for IRDN-B, and 10(-2) and 1.0 for chloroquine.
The corresponding values for the W2 strain were 10(-5) and 1.0 for IRDN-A, and 10.0 and >100 for chloroquine (even at 100 microg/ml, chloroquine only inhibited the parasitaemia by 85%).
Each of the two neem-leaf fractions lysed 50% and 100% of developing gametocytes, at 10(-3) and 1.0 microg/ml, respectively; and 50% and 100% of mature gametocytes at 10(-3) and 10(2) microg/ml, respectively.
If they are found safe and effective in vivo, the neem-leaf fractions may form the basis of new antimalarial drugs that not only cure chloroquine-sensitive and chloroquine-resistant malaria but also markedly reduce transmission.
PMID: 16417709
-------------------- There is no wealth but life. -John Ruskin
All truth goes through 3 stages: first it is ridiculed: then it is violently opposed: finally it is accepted as self evident. - Schopenhauer Posts: 5639 | From Aptos CA USA | Registered: Apr 2005
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I am happy to hear that neem is being mentioned. I used it early on in my disease as well and found it to be helpful.
It is also helpful in maintaining a lower blood sugar level. It is available on the web but if you know of any indian community you will be able to get it pretty affordably.
kindly,
Julia
-------------------- Please consult your LLMD before making any changes to your treatment regimen. Posts: 641 | From NJ, USA | Registered: Oct 2001
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I have used neem and eucalyptus for babesia. It seems to work well for these issues. I only tried it after I was better from a lot of things already, though, so I don't know how effective it would be on more severe Lyme. It also seems to help clear up symptoms under the skin. Neem is known for clearing skin infections in India.
Farah
Posts: 208 | From New Mexico | Registered: Dec 2005
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up
Posts: 641 | From Nevada | Registered: May 2009
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Lauralyme
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My LLMD has me take Neem.....one cap three times a day
It's an inexpensive supplement
-------------------- Fall down seven times, get up eight ~Japanese proverb Posts: 1146 | From west coast | Registered: Mar 2008
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lululymemom
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It's used in the Byron White Formula A-Bab..
Neem: This herb's anti-viral, anti bacterial and anti-fungal effects are well documented. Evidence exists for its use in pneumonia, ulcers, gout, diabetes, hypertension, skin infection and wound healing. The essential fatty acid content in Neem is high.
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