Tincup
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If one of your coinfections is parvovirus, this may be of interest.
Virology. 2013 Nov;446(1-2):173-9. doi: 10.1016/j.virol.2013.06.022. Epub 2013 Aug 28. Human parvovirus B19 infection leads to downregulation of thyroid, estrogen, and retinoid hormone receptor expression. Ignatovich IV1, Hobbs JA. Author information
1Department of Psychiatry, College of Medicine, University of Florida, 1200 Newell Road, R1-136, Gainesville, FL 32610, USA; Department of Pediatrics, College of Medicine, University of Florida, 1200 Newell Road, R1-136, Gainesville, FL 32610, USA; Department of Molecular Genetics and Microbiology, College of Medicine, University of Florida, 1200 Newell Road, R1-136, Gainesville, FL 32610, USA. Electronic address: [email protected]. Abstract
Erythrovirus B19 (B19V) is a member of the family Parvoviridae.
Infection with B19V has been linked to a variety of diseases including erythroid, thyroid, neurological and autoimmune diseases.
Here we show that infection of primary CD36+ cells with B19V coincides with downregulation of thyroid, retinoid, and estrogen hormone receptors.
In addition we show changes in expression of a variety of related downstream signaling genes participating in cancer and cardiac-related diseases in B19V-infected erythroid primary cells.
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