I also am on 1000mg of Biaxin daily but in addition I take Ceftin 500mg daily.

You need both types of antibiotics to combat the cystic form of the disease as well.

Lyme is polymorphic, meaning that it changes its structure. It hides out in organs, muscles, bloodstream, etc. In the chronic stages, the lyme bacteria builds a protective shell around itself - a cyst, which makes treating it very difficult. Doxy for example won't put a dent in cystic lyme.

The theory is that you need two meds when the lyme is cystic - one that will rupture the cyst, and the other to suck the life out of the lyme bacteria when it comes creeping out. So biaxin only works on one part of that process.....

This is where I come up short...don't know which biaxin does - the rupturing or sucking. Now in my case, I'm using tinidazole and biaxin. These two in combination deliver the one-two punch. I am seeing improvement - slow and steady but moving forward nonetheless.

Sorry....I'm one of the lesser drug knowledgabele lymies here....I defer to my lyme doc. He's great about explaining how everything works, and I get it, but once I leave the appt, I forget.....

In fact, Ceftin and other cephalasporins may cause the spirochete to morph into the cyst form.

The cyst form is also called the cell wall deficient or L form. The spirochetes have been shown to change into it when under adverse conditions.

Rocephin, Ceftin and Omnicef are cell wall inhibiting antibiotics, and can create the kind of environment where this happens. When in the cyst form, Bb is not vulnerable to most antibiotics.

Flagyl, Tinidazole, and Plaquenil are often used for the cyst form. It's believed that they don't actually kill the cysts, but they force them out of cyst form so your other antibiotics can kill them.

Kevin, many doctors will use combinations of antibiotics to be more effective. Look in Dr. Burrascanno's protocol. It is especially good to use two that have complementary modes of action. Biaxin and Ceftin is one example of that.