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» LymeNet Flash » Questions and Discussion » Medical Questions » Are Trypanosomes another possible tick-borne parasite?

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Author Topic: Are Trypanosomes another possible tick-borne parasite?
AliG
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Trends in Parasitology
Volume 24, Issue 10, October 2008, Pages 428-431

What happens when Trypanosoma brucei leaves Africa

Robert E. Jensen1, Larry Simpson2 and Paul T. Englund3,
1Department of Cell Biology, Johns Hopkins Medical School, Baltimore, MD 21205, USA 2Department of Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, CA 90095, USA 3Department of Biological Chemistry, Johns Hopkins Medical School, Baltimore, MD 21205, USA

Available online 18 August 2008.

References and further reading may be available for this article. To view references and further reading you must purchase this article.


Julius Luke� and co-workers evaluated the evolutionary origin of Trypanosoma equiperdum and Trypanosoma evansi, parasites that cause horse and camel diseases.

Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cycle through the tsetse fly and have been able to spread beyond Africa.

Transmission occurs sexually, or via blood-sucking flies* or vampire bats.

They concluded that these parasites, which resemble yeast petite mutants, are T. brucei sub-species, which have evolved recently through changes in mitochondrial DNA.

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*- anyone else wonder if this could also be TICK-transmitted? [Eek!]

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Note: I'm NOT a medical professional. The information I share is from my own personal research and experience. Please do not construe anything I share as medical advice, which should only be obtained from a licensed medical practitioner.

Posts: 4881 | From Middlesex County, NJ | Registered: Jul 2006  |  IP: Logged | Report this post to a Moderator
Melanie Reber
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Title
A trypanosome species isolated from naturally infected Haemaphysalis hystricis ticks in Kagoshima Prefecture, Japan.

Author(s)
Thekisoe OM, Honda T, Fujita H, Battsetseg B, Hatta T, Fujisaki K, Sugimoto C, Inoue N

Institution
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan.

Source
Parasitology 2007 Feb 19.:1-8.

Abstract
Common arthropod vectors for trypanosomes are flies, fleas and bugs. This study reports on an unknown trypanosome species isolated from naturally infected Haemaphysalis hystricis ticks, hereby, referred to as Trypanosoma KG1 isolate. The parasite has been successfully cultured in vitro with L929 or HEK 293T cell line as feeder cells. This trypanosome cannot survive in vitro without feeder cells. Following experimental infections of ticks, the trypomastigote-like and the epimastigote-like forms of this trypanosome could be detected by Giemsa-stained smears of the midgut and salivary glands of Ornithodoros moubata ticks which were made to feed on a culturing medium containing Trypanosoma KG1 isolate through an artificial membrane.

Trypanosoma KG1 isolate could also be detected from Giemsa-stained smears of the haemolymph up to 30 days post-inoculation into the O. moubata haemocoel. Trypanosoma KG1 isolate cannot be propagated in laboratory animals including mice, rats, rabbits and sheep. A phylogenetic tree constructed with the 18S rRNA gene indicates that Trypanosoma KG1 is a member of the stercorarian trypanosomes.

Language ENG
Pub Type(s) JOURNAL ARTICLE
PubMed ID 17306058

...

I'm sure there are more references, I just stopped at the first I found. So, yes, it IS tickborne.

Posts: 7052 | From Colorado | Registered: Mar 2003  |  IP: Logged | Report this post to a Moderator
lymie tony z
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Yeah well why not? It's a blood feeder vector the tse tse fly!

which usually causes sleeping sickness in humans....

two out of the many forms of trypanosomes, have a way of getting around human INNATE defences against them...

are'nt humans lucky!....LOL!

zman

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I am not a doctor...opinions expressed are from personal experiences only and should never be viewed as coming from a healthcare provider. zman

Posts: 2527 | From safety harbor florida(origin Cleve., Ohio | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
   

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