posted
I have my Igenex test results back. The stuff that wasn't the Western blot was all negative.
For the Western Blot, it was overall negative.
IgM: **41 kDa + The rest were negative
IgG **39 kDA IND **41 kDA ++ The rest were negative.
I know 41 on it's own isn't very specific, but with the IND on the 39, is it enough to point to Lyme?
My lyme doc says so, and I think I agree with her. I was just hoping for some concrete proof.
Posts: 503 | From Alberta, Canada | Registered: Jun 2009
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"Band 39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all."
From Dr C's WB explanation:
"Many would say the " +/-" equivocal ["IND"] bands are not significant. The problem I have with that, is that there are "-" negative bands. The lab has no trouble calling some bands negative. So they must be seeing something when they put "+/-" [IND] at some bands.
The only thing that makes sense, is that there is a little bit of that antibody present in your serum. If the "+/-" equivocal [IND] is reported on the borrelia associated bands, it is usually significant, in my clinical experience. This is a strong clue that I am on the right track."
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96227 | From Texas | Registered: Feb 2001
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posted
That's almost the same as my result, except my IgG 39 was a + not an IND. I ruled everything else out, and 7 months into treatment, I am getting better.
Posts: 455 | From Was in PA, then MD, now in the Midwest | Registered: Nov 2008
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posted
Be sure to read Dr C's WB explanation including all the replies to it!
Print it out!
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96227 | From Texas | Registered: Feb 2001
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seekhelp
Frequent Contributor (5K+ posts)
Member # 15067
posted
Tough one. I've read Dr. C's explanation thoroughly. I'm not sure I could buy into it totally. I'd be checking other stuff too, but strongly considering Bb and see how you react.
Posts: 7545 | From The 5th Dimension - The Twilight Zone | Registered: Mar 2008
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Leelee
Frequent Contributor (1K+ posts)
Member # 19112
posted
If you have symptoms your test results could definitely point to Lyme. Remember that not all of us make or show the antibodies to Lyme.
-------------------- The ultimate measure of a man is not where he stands in moments of comfort and convenience, but where he stands at times of challenge and controversy. Martin Luther King,Jr Posts: 1573 | From Maryland | Registered: Feb 2009
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posted
I agree with seek help to test for other stuff too, but continue with Lyme treatment. I have tested for everything any Dr could think of. I'm sure there's still something out there I haven't tested for but I don't know what that could be. At this point Lyme makes the most sense and fits the best.
-------------------- Sofi Posts: 150 | From Northern California | Registered: Jun 2009
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posted
Seek .. You can't buy into Dr C's explanation? Then you may as well throw out everything that Dr B said as well.
-------------------- --Lymetutu-- Opinions, not medical advice! Posts: 96227 | From Texas | Registered: Feb 2001
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sutherngrl
Frequent Contributor (1K+ posts)
Member # 16270
posted
My doc says that unless Lyme changes its DNA and mutates, that it will FOREVER be a CLINICAL diagnosis.
It gets too deep into our cells to be detected and that is why so many of us test negative.
Posts: 4035 | From Mississippi | Registered: Jul 2008
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timaca
Frequent Contributor (1K+ posts)
Member # 6911
posted
Depending on your symptoms, consider getting tested for other pathogens such as EBV, enterovirus, HHV-6 and Cpn.
I don't think you have enough serological evidence to support a lyme diagnosis.
Best, Timaca
Posts: 2872 | From above 7,000 ft in a pine forest | Registered: Feb 2005
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Pinelady
Frequent Contributor (5K+ posts)
Member # 18524
posted
"Band 39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all."
If you did not challenge I would not expect any
thing more than what you got. My first test only
got one band unable to identify. So they say.
And I do so wish I had been treated. No matter
what some think You do have something with
flagella and with symptoms should be treated.
-------------------- Suspected Lyme 07 Test neg One band migrating in IgG region unable to identify.Igenex Jan.09IFA titer 1:40 IND IgM neg pos 31 +++ 34 IND 39 IND 41 IND 83-93 + DX:Neuroborreliosis Posts: 5850 | From Kentucky | Registered: Dec 2008
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