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» LymeNet Flash » Questions and Discussion » Medical Questions » Bands I tested positive to . . . please help

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Author Topic: Bands I tested positive to . . . please help
lymelupus
Junior Member
Member # 24561

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Hi,
I have been reading a lot of info here and would like to now if the bands I tested positive to are Lyme specific
41 kDa
66 kDa
23 kDa
41 kDa
18 kDa

The IgM Interp. said
Positive IGM antibodies to significand B. Burgdorfe
RI proteins detecte ABN - 1

Lyme IgG and IgM
Positive lyme antibody IgG and IgM
Test Value Threshold Interpretation
<ABN -1

Does all of this mean it is absolutely Lyme and not something else, viral etc?

Thanks for any help

Posts: 9 | From nashua, nh 03062 | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
dmc
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Wow. It's a Lyme test and it says positive both IgM & IgG. It's very clear.
Posts: 2675 | From ct, usa | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
susank
Frequent Contributor (1K+ posts)
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What testing lab did you use?

--------------------
Pos.Bb culture 2012
Labcorp - no bands ever
Igenex - Neg. 4 times
With overall bands:
IGM 18,28,41,66 IND: 23-25,34,39
IGG 41,58 IND: 39
Bart H IGG 40

Posts: 1613 | From Texas | Registered: Aug 2009  |  IP: Logged | Report this post to a Moderator
lymelupus
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The dr used Quest Diagnostic
Posts: 9 | From nashua, nh 03062 | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
dmc
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That's even more of a wow. Quest is notorious for false negatives.
Posts: 2675 | From ct, usa | Registered: Jan 2004  |  IP: Logged | Report this post to a Moderator
lymelupus
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so I take it from your response that this is definitly Lyme?
Posts: 9 | From nashua, nh 03062 | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
Pinelady
Frequent Contributor (5K+ posts)
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I agree. Quest may have finally learned how to do it right.

Did you do a challenge with antibiotics?

How long have you been misdiagnosed with Lupus?

Do you have a LLMD to treat?

Prayers for a easy road to wellness.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

Posts: 5850 | From Kentucky | Registered: Dec 2008  |  IP: Logged | Report this post to a Moderator
lymelupus
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I don't know what a challenge with antibiotics means? I am currently taken doxy have been on it for two weeks and have two weeks more to go.

I have had these symptons for 16 years but always have tested neg to the western blot until recently.

My primary initially diagnosed me and then sent me to an id dr. We are questioning the length of treatment - one month - as this has been going on for quite some time and I have been very ill since last feb.

That is why I have sought help from people who are actually living with this. I was e-mailed some LLMD dr in my state but I am just not sure what to do.

Thanks for your reply any advice would be helpful.

Posts: 9 | From nashua, nh 03062 | Registered: Feb 2010  |  IP: Logged | Report this post to a Moderator
Lymetoo
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A challenge means taking 3-4 wks of abx then going off for 10 days... then doing the test.

Is that basically what happened? I wonder if your test finally showed positive because you were on abx?

Read here about the Western Blot... I'll be back in a minute.. so refresh your screen.

Western Blot Explanation
http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/42077

From the WB explanation.....

"The following is a brief explanation of the test results. Again, each band is an antigen complexed (bound together) with an antibody made by the immune system, specifically for that antigen (part) of Borrelia burgdorferi.

18: An outer surface protein.

22: Possibly a variant of outer surface protein C.

23-25: Outer surface protein C (osp C).

28: An outer surface protein.

30: Possibly a variant of outer surface protein A.

31: Outer surface protein A (osp A). 34: Outer surface protein B (osp B).

37: Unknown, but it is in the medical literature that it is a borrelia-associated antibody. Other labs consider it significant.

39: Unknown what this antigen is, but based on research at the National Institute of Health (NIH), other Borrelia (such as Borrelia recurrentis that causes relapsing fever), do not even have the genetics to code for the 39 kDa antigen, much less produce it. It is the most specific antibody for borreliosis of all.

41: Flagella or tail. This is how Borrelia burgdorferi moves around, by moving the flagella. Many bacteria have flagella. This is the most common borreliosis antibody.

45: Heat shock protein. This helps the bacteria survive fever. The only bacteria in the world that does not have heat shock proteins is Treponema pallidum, the cause of syphilis.

58: Heat shock protein.

66: Heat shock protein. This is the second most common borrelia antibody.

73: Heat shock protein.

83: This is the DNA or genetic material of Borrelia burgdorferi. It is the same thing as the 93, based upon the medical literature. But laboratories vary in assigning significance to the 83 versus the 93.

93: The DNA or genetic material of Borrelia burgdorferi.

In my clinical experience, if a patient has symptoms suspicious for borreliosis, and has one or more of the following bands, there is a very high probability the patient has borreliosis.

These bands are 18, 22, 23-25, 28, 30, 31, 34, 37, 39, 41, 83, and 93.

+++++++++++++++++++++

FROM 2005...
The significant antibodies, in my opinion, are the 18, 23-25, 28, 30, 31, 34, 39, 58, 66 and 93." ----Dr C of MO

++++++++++++++

Combine this information with your SYMPTOMS. A clinical diagnosis is what is most important.

Skip the ID duck and go for a real dr.. one who will treat you until you are well. I guarantee you will not be well in one month. Sad to say!!

Glad you found Lymenet! Now you can be on your way to recovery!! [Smile]

--------------------
--Lymetutu--
Opinions, not medical advice!

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Pinelady
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You may want to get copies of all your old tests. Many have been told neg. when in fact they had

specific bands that were dismissed when they should not have been, because the IDSA and CDC told them

they had to have so many bands to be positive.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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Karen Mc
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Trust me from someone who knows.... YOU WILL NEED MORE THAN 4 WEEKS OF ABX TREATMENT!!!!!!!!

It is VERY IMPORTANT that you find a LLMD. Obviously this has been going on for years (probably in the background) and now that it getting worse and you HAVE tested POSITIVE for lyme you need to try to get a handle on this.

I went for years also--not having ANY idea I had Lyme and co-infections...but looking back now ALL the signs were there--just too sutle to put together until I got so sick I COULD NOT HOLD MY HEAD UP.

I still have a long way to go, but I have also come ALONG way compaired to April 2009 when I finally saw a LLMD.

So PLEASE, get help...there is hope!!!


God Bless and good luck,

Karen (:

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Lymetoo
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Where's Lymelupus??

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96227 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
Pinelady
Frequent Contributor (5K+ posts)
Member # 18524

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I would guess they are as shocked as I was to

finally find what was making them sick.

--------------------
Suspected Lyme 07 Test neg One band migrating in IgG region
unable to identify.Igenex Jan.09IFA titer 1:40 IND
IgM neg pos
31 +++ 34 IND 39 IND 41 IND 83-93 +
DX:Neuroborreliosis

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Lymetoo
Moderator
Member # 743

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up

--------------------
--Lymetutu--
Opinions, not medical advice!

Posts: 96227 | From Texas | Registered: Feb 2001  |  IP: Logged | Report this post to a Moderator
   

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