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» LymeNet Flash » Questions and Discussion » Medical Questions » my igenix test results what do you think

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Author Topic: my igenix test results what do you think
Maya12
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So here are my igenix reuslts: lyme IgM western. Blot : igenix IgM result : positive
CDC Result: negative

Bands: 18kDa -
23-25 kDa -
28kDa -
30kDa -
31kDa +++
34kDa indeterminate
39kDa indeterminate
41kDa ++
45kDa -
58kDa -
66kDa -
83-93kDa +

Igenix IGG western blot was negative

What does this all mean, I know I have lyme but could someone please interpret the bands for me thanks.

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bcb1200
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Band 31 positive. It is very lyme specific and takes at least a year to show up. You've had it a while.

41 is not specific to lyme. It is the flagella (tail) but is also common in other bacteria.

83/93..lyme DNA. nothing else will cause this to be positive but lyme.

You have it.

--------------------
Bite date ?
2/10 symptoms began
5/10 dx'd, after 3 months numerous test and doctors

IgM Igenex +/CDC +
+ 23/25, 30, 31, 34, 41, 83/93

Currently on:

Currently at around 95% +/- most days.

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Lymetoo
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Western Blot Explanation
http://flash.lymenet.org/ubb/ultimatebb.php/topic/1/42077

from the above link:

"With most infections, your immune system first forms IgM antibodies, then in about 2 to 4 weeks, you see IgG antibodies. In some infections, IgG antibodies may be detectable for years.

Because Borrelia burgdorferi is a chronic persistent infection that may last for decades, you would think patients with chronic symptoms would have positive IgG Western blots.

But actually, more IgM blots are positive in chronic borreliosis than IgG. Every time Borrelia burgdorferi reproduces itself, it may stimulate the immune system to form new IgM antibodies.

Some patients have both IgG and IgM blots positive. But if either the IgG or IgM blot is positive, overall it is a positive result.

Response to antibiotics is the same if either is positive, or both. Some antibodies against the borrelia are given more significance if they are IgG versus IgM, or vice versa.

Since this is a chronic persistent infection, this does not make a lot of sense to me. A newly formed Borrelia burgdorferi should have the same antigen parts as the previous bacteria that produced it.

But anyway, from my clinical experience, these borrelia associated bands usually predict a clinical change in symptoms with antibiotics, regardless of whether they are IgG or IgM."
--


BAND 83: This is the DNA or genetic material of Borrelia burgdorferi. It is the same thing as the 93, based upon the medical literature. But laboratories vary in assigning significance to the 83 versus the 93.

BAND 93: The DNA or genetic material of Borrelia burgdorferi.

--------------

Yes, you've had this awhile.

--------------------
--Lymetutu--
Opinions, not medical advice!

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Maya12
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Oh geeze I wonder how long I have had it , I just really hope I can get rid of it even if I have had it for a long time. I wonder how long I have had it.

Is there less of a chance of recovering if you have had it longer.

I know others have had it a long time though and recovered

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Lymetoo
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Many of us had it a long long time and recovered. There is hope!

--------------------
--Lymetutu--
Opinions, not medical advice!

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Maya12
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Thanks lyme too I really appreciate it and do have hope also I got another cancelation for my llmd first visit and now am going on april 17th.
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Maya12
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I forgot to mention that my cd57 was 41

Also all I am doing with my nd until I see my llmd is taking milk thistle , alpha lipoid acid and a supplement called nac which has acetyl l cystine and vit c in it , these are to help me detox apparently. He as also suggested doing oxygen therapy to kill some Lyme and parasites as an adjunct to what my llmd will do. What do you guys think about these supplements and the oxygen therapy?

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