posted
For anyone that does not know -- I have a weird hobby. I like to read health books.
I just got a copy of a new book in the mail -- Hashimoto's Thyroiditis: Lifestyle Interventions for Finding and Treating the Root Cause.
The book does a really good job of explaining all the possible coinfections/triggers for the thyroid issues. Quote from page 117 -- A variety of bacterial infections have been implicated in triggering autoimmune thyroiditis, including H. pylori, lyme, and Yersinia enterocolitica.
Antibodies to Yersinia (indicating exposure) in people with Hashimoto's were found 14 times more often than in people without Hashimoto's. -- end quote
Yersinia is a parasite and the test is an add on test for comprehensive stool analysis.
The book also talks about viral causes and leaky gut and lots of other related health issues. Has one of the best explanations of the TH1 and Th2 immune system I have seen.
I would suggest anyone with Hashimoto's get a copy of this book.
seibertneurolyme
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poppy
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Those of us with this condition get told by some self appointed experts that taking iodine is bad for us, makes it worse, but I read a study where this was tested and found not to be true. Will post if anyone wants it and I can find it again.
It never made a lot of sense because iodine is needed to make T3, and these days a lot of us are being exposed unwillingly to fluoride and bromine which take up receptors and block the iodine we do get from foods.
[ 03-14-2014, 11:14 PM: Message edited by: poppy ]
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posted
Poppy lots of refernces to iodine in the book. It also has a 3 page chart listing iodine content of food.
These are the bullet points in the summary of the chapter on the iodine controversy.
1) Iodine perpetuates the autoimmune attack
2) Check iodine levels
3) If normal/high iodine levels, consider limiting iodine to less than 100 mcg per day for 3 months and then retesting TPO antiboidies.
The book does cite medical journal articles and interviews with "experts" to back up all info presented.
Bea Seibert
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poppy
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Enhanced iodine supplementation alters the immune process in a transgenic mouse model for autoimmune thyroiditis
To cite this article: Mrs. Margret Ehlers, Dr. Annette Thiel, Dr. Claudia Papewalis, Mr. Andreas Domroese, Ms. Wiebke Stenzel, Dr. Christian Bernecker, Dr. Matthias Haase, Dr. Stephanie Allelein, Dr. Sven Schinner, Dr. Holger Willenberg, Dr. Joachim Feldkamp, and Dr. Matthias Schott. Thyroid. -Not available-, ahead of print. doi:10.1089/thy.2013.0495.
Online Ahead of Editing: January 24, 2014
Full Text PDF (539.5 KB) Full Text PDF with Links (537.3 KB)
Author information Mrs. Margret Ehlers, Dr. Heinrich-Heine University Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Annette Thiel University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Claudia Papewalis University Hospital Duesseldorf, Department of Paediatric Oncology, Haematology and Immunology, Duesseldorf, Germany; [email protected] Mr. Andreas Domroese University Duesseldorf, Department of Functional Genomics of Microorganisms, Duesseldorf, Germany; [email protected] Ms. Wiebke Stenzel University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Christian Bernecker University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Matthias Haase University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Stephanie Allelein University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Sven Schinner University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Holger Willenberg University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Dr. Joachim Feldkamp Municipal Hospital Bielefeld, Department for Endocrinology and Diabetes, Bielefeld, Germany; [email protected] Dr. Matthias Schott University Hospital Duesseldorf, Division for Specific Endocrinology, Duesseldorf, Germany; [email protected] Accepted: 08 27 2013 Received: 08 27 2013 ABSTRACT
Background: The impact of excessive iodine intake on the development of autoimmune thyroiditis (AIT) is still under debate. Transgenic, antibody devoid, TAZ10 mice spontaneously develop AIT due to autoreactive thyreoperoxidase-specific T cells. In this model, development of AIT is determined by a T cell infiltration of the thyroid gland leading to an elevation of serum TSH-levels and a significant gain in weight. In the present study we investigated the impact of moderate and high iodine supplementation on the course of disease in these mice which are immunologically prone to AIT.
Methods: In addition to normal nutrition, mice were supplemented for 20 weeks with 2.5 µg vs. 5 µg iodine per ml drinking water which equates to a humans’ daily iodine supplementation of 150 µg, 315 µg, and 615 µg iodine. AIT defining parameters (gain in weight, elevation of serum TSH-levels, cellular infiltration of the thyroid) and immunological effects were analyzed.
Results: No significant differences were displayed when comparing weight and serum TSH-levels in the iodine supplemented versus control groups. Increased thyroid infiltrates with CD8+ T cells were detected by FACS and immunofluorescence staining in mice supplemented with elevated iodine amounts (315 µg respectively 615 µg iodine per day). Immunological monitoring revealed selectively changes in immune cell frequencies (CD8+ and regulatory T cells, NK cells) and cytokine production (interferon-gamma, interleukin 1α and 17), however, without affecting the overall immune balance.
Conclusion: Our results demonstrate that elevated iodine supplementation has no physical impact on the course of disease in transgenic, antibody devoid, TAZ10 mice which are immunologically prone to AIT.
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poppy
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I realize that mice are not people, but it has never made any sense to me that we would keep being exposed to bromine and fluorine which reduce the amount of iodine available to make T3, but then not supplement with iodine to counteract this.
See this:
Triiodothyronine (T3) is a thyroid hormone
iodo=iodine
[ 03-14-2014, 11:15 PM: Message edited by: poppy ]
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