posted
Ivermectin is really effective at dealing with my protozoan problems, and parasites, mostly, too, but I'm afraid that if I take it for 3 or 4 months continuously, even only once a week, the bugs will adapt to it, and it will stop being effective.
Any input would be appreciated.
Posts: 242 | From durham, nc | Registered: Oct 2016
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posted
My brother in law has taken it on and off for years and hasn't developed resistance yet. It really works for him.
Best wishes!
Posts: 477 | From Pennsylvania | Registered: Nov 2015
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Catgirl
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posted
The bug I take it for adapts to it, but I don't take it once a week, I take it for about a week then go onto another med. Why just once a week?
-------------------- --Keep an open mind about everything. Also, remember to visit ACTIVISM (we can change things together). Posts: 5418 | From earth | Registered: Mar 2011
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posted
I had parasites once for a long, long time, maybe a year. It was the most hopeless and helpless feeling that I've ever had. I tried every remedy there was. I took Hulda Clark remedies, Wormwood capsules and Black Walnut and Cloves, an African herb and a Mexican herb as well as remedies that I don't even remember the name of,
but nothing did the least bit of good. Until one weekend, I opened an Artemisinin capsule and poured it into a cup of boiling water, added sweetnener and drank it as a tea. Then on Sunday, I had a second cup of Wormwood (Artemisinin) tea and ... I was cured!!!! It was something
about the hot tea that must have permeated every recess of my body. This was many years ago.
Posts: 653 | From Northern Virginia | Registered: Oct 2014
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posted
I'd read up on scientific studies on Filiariasis--- especially cutaneous filiariasis such as onchocerca and loa loa. You will get a depth of knowledge of HOW these bugs work and breed- which will help you decide on when, and how much ivermectin or fenbendazole to take.
Typically about 50 tiny adult female worms will hold up in a small bump or "pod" under the skin usually over a boney area such as the scalp or forearm. It will look like a "bump." Females produce up to 1500 little larvea or juveniles per day. These juveniles migrate to the skin and wait for an insect such as a tick, biting fly or mosquito to transmit them somewhere else. Their die off (juveniles) causes massive itching and/or sores. The juveniles are the only ones that are susceptible to ivermectin -- NOT THE ADULTS. But ivermectin if given once every 3 or 4 months will keep the juvenile level very low in your skin, thus treating the condition. Adults however live for up to 14 years--- so you are not cured until you kill of adults. You can surgically remove the pods to get many of the adults.
The real solution however is to find an agent that kills adults. Doxycycline will sterilize some filarial species that are dependent on the wolbachia bacteria because doxy kills wolbachia, hence sterlizing the worms. No more breeding.
But the A. Viteae filarial found in deer ticks does not harbor wolbachia.
See the second page of my thread for more links on these worms--- (Spirochaetecidal compounds thread) for lots of links to scientific research on these horrific filarial worms. These types of worms can also host borrelia and bartonella-- kind of like the gift that keeps on giving..
They are like little biowarfare agents! I doubt that anyone can be cured of Lyme or bartonella until they deworm and eliminate filarial worms.
Posts: 696 | From New York | Registered: Aug 2006
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posted
Here is some information on the filarial worm-- A. Viteae --- that has been found in deer ticks--- remember that to cure a filarial infection you need both a MACROFILARICIDAL and and MICROFILARICIDAL drug.
Ivermectin is a microfilaricide and it WILL NOT KILL adult worms, only the juveniles that cause most symptoms..
Adults live for up to 12-14 years...
Yes.... we are sooo $crewed!!
Acanthocheilonema viteae--
A. Viteae is a rodent Filarial worm identified in deer ticks which may also harbor borrelia burgdorferi DNA, rickettsia-like organisms, and bartonella-like organisms. A. Viteae has Onchocerca-like characteristics. It is not known whether this worm can infect human beings. Unlike other filaria, it is not dependent on the wolbachia bacteria, hence doxycycline probably does not work to sterllize A. Viteae.
Research on filariacidal drugs effective against Acanthocheilonema viteae.
PEER REVIEW SCIENCE "Experimental chemotherapy of filariasis: comparative evaluation of the efficacy of filaricidal compounds in Mastomys coucha infected with Litomosoides carinii, Acanthocheilonema viteae, Brugia malayi and B. pahangi. Zahner H1, Schares G. LINK: https://www.ncbi.nlm.nih.gov/pubmed/8094587
"Abstract Eleven types/classes of compound with antifilarial activity were comparatively evaluated in Mastomys coucha infected with Litomosoides carinii, Acanthocheilonema viteae, Brugia malayi or B. pahangi. The paper deals with the efficacy of (i) predominantly microfilaricidal compounds [diethylcarbamazine, levamisole, avermectins (ivermectin, milbemycin), nitrofurans (nitrofurantoin, hydroxymethylnitrofurantoin, nifurtimox, furazolidone, furapyrimidone), organophosphorals (metrifonate, haloxon), and aminophenyl-amidines], (ii) predominantly macrofilaricidal compounds [suramin, benzimidazoles (flubendazole, mebendazole, oxfendazole, ciclobendazole, albendazole, cambendazole, fenbendazole), and arsenicals (thiacetarsamide, Mel PH, R7/45)], and (iii) micro- and macrofilaricidal compounds [benzazole derivatives (CGP 20376 and other benzothiazoles) and nitrophenylamines (amoscanate, CGP 6140)]. Minimum effective doses against microfilariae and minimum curative doses against adult filariae as well as detailed data on dose-efficacy relationships are reported for the various drugs. The results obtained in M. coucha are compared with those published for other experimental in vivo filarial systems, thus attempting to describe a general status of in vivo antifilarial activity of the compounds." ------------
"Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin," Debrah A.Y., Mand S., Marfo-Debrekyei Y., Larbi J., Adjei O. and Hoerauf A. Debrah A.Y., Mand S., Marfo-Debrekyei Y., Larbi J., Adjei O. and Hoerauf A. Filaria Journal 2006 5:- (10p)
[ 10-14-2016, 03:57 PM: Message edited by: WakeUp ]
Posts: 696 | From New York | Registered: Aug 2006
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Catgirl
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posted
Fascinating Wakeup! Thank you for posting.
GVS, after reading Wakeup's post, I doubt once a week is going to kill them off.
-------------------- --Keep an open mind about everything. Also, remember to visit ACTIVISM (we can change things together). Posts: 5418 | From earth | Registered: Mar 2011
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quote:Originally posted by Catgirl: Fascinating Wakeup! Thank you for posting.
GVS, after reading Wakeup's post, I doubt once a week is going to kill them off.
Thanks catgirl!!
As far as dosing, I think the scientific papers show that a SINGLE dose of Ivermectin will keep the juveniles at bay for at least 3-6 months. Ivermectin apparently causes the environment to be inhospitable/ fatal to the juvenile worms for at least a few months.
Ivermectin, however will not kill adult worms, as I mentioned above, so probably would need to be taken at least 3 times per year just to keep the juvenile population down. Ivermectin would need to be taken 3 times per year, for 12 years in order to cure a person, since the breeding adults live that long..
The lifecycle of these nematodes is really complicated, and the fact that they can harbor borrelia and bartonella means that they must be eliminated if we are to achieve a cure. They also suppress the immune system.
But I am not a doctor, I just research scientific journals as a hobby-- so nothing I say is medical advice-- just research.
Posts: 696 | From New York | Registered: Aug 2006
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posted
Azadirachtin (the main chemical in NEEM) may work similarly to IVERMECTIN --- doesnt kill microfilaria, but does inhibit adults from releasing microfilari-- so is actually better than ivermectin.
NEEM inhibits release of microfilaria, according to a scientific study:
Effects of potential inhibitors on Brugia pahangi in vitro: macrofilaricidal action and inhibition of microfilarial production, by Barker GC1, Mercer JG, Svoboda JA, Thompson MJ, Rees HH, Howells RE.
ABSTRACT: A series of compounds that apparently disrupt hormonally regulated processes in insects have been examined for effects on the viability and microfilarial production of adult Brugia pahangi cultured in vitro. The azasteroids, 25-azacoprostane and 25-azacholestane, inhibited the production of microfilariae at 5 ppm, the former also exhibiting macrofilaricidal activity at this concentration. The brassinosteroids examined inhibited microfilarial production at 5 ppm but did not affect worm viability. Azadirachtin also proved to be a significant inhibitor of microfilarial release without effect on worm motility or viability. Of all the compounds tested, the non-steroidal amines appeared to be the most promising as potential filaricides, several of them proving to be macrofilaricidal at 1 ppm and affecting microfilarial production at even lower concentrations.
Posts: 696 | From New York | Registered: Aug 2006
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Catgirl
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posted
Thanks Wakeup (encouraging about neem)!
The first abstract you posted does not say what the minimum effective or curative doses were though or for how long. I read something earlier that showed they tested for 4 to 6 weeks, so maybe that was considered a dose period, but still the milligrams are not identified above. Maybe I'm missing something.
GVS, I know the Dr. K protocol starts out at 6 weeks. I have been on iver for several years and one pill never did anything for me, but after six weeks, I did feel better.
-------------------- --Keep an open mind about everything. Also, remember to visit ACTIVISM (we can change things together). Posts: 5418 | From earth | Registered: Mar 2011
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sparkle7
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posted
Thanks WakeUp. That's great info... I've been dealing with this for about 20 years. It took me a long time to realize it was a parasite issue.
Do you know if there's any good testing to find out which parasite we are dealing with?
I did all kinds of treatments but the only things that ever worked for me was anti-parasite herbs. They do keep coming back, though.
I will definitely look into neem. I prefer herbal treatments.
Posts: 7772 | From Northeast, again... | Registered: Oct 2006
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I need recommendations for ordering drugs like these without an Rx. I've had trouble finding a doctor who is willing to prescribe based on horrible symptoms like Oncherous Volvulus in head and babesia among other international bugs due to lack of blood tests for international species. Has anyone used an international pharmacy they feel comfortable with? I've used Canadian pharmacies with Rx. But my dr is stopping all meds so I'm left with option of vet meds and trying to find an international pharma, which seems risky and not ideal. Ideas? Message me if names cannot be posted? Microfilials suck.
Posts: 1 | From Gainesville, FL | Registered: Oct 2016
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bluelyme
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posted
Welome blitzen ...i think ebay and amazon are going to be your best bet ...maybe adc has it in stock again
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