oops! Lymetutu
I have a consult with Dr. J soon, but can anyone give me a little insight into any details these results might indicate.
thanks.
IGG
18 kda +
22 kda -
23-25 kda +/-
28 kda -
30 kda +
31 kda +/-
34 kda +
37 kda -
39 kda +
41 kda + + + +
45 kda +
58 kda +/-
66 kda + +
73 kda -
83 kda -
93 kda +/-
IGM
18 kda +
22 kda -
23-25 kda +/-
28 kda +
30 kda +/-
31 kda -
34 kda -
37 kda -
39 kda +
41 kda +/-
45 kda +
58 kda +/-
66 kda +
73 kda -
83 kda -
93 kda +
You're in good hands with Dr Jones. Let us know if we can help you with anything else. The following link has excellent information on the Western Blot interpretation, including the significance of each band.
Western Blot explanation: http://flash.lymenet.org/ubb/Forum1/HTML/022767.html
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oops!
Lymetutu
My daughter was equivocal too a that time, she got cured by Dr. J years a go.
In this link you will find answers for your questions.
http://www.personalconsult.com/articles/drjonesapproach.html
When is the apointment?
quote:Looks guilty as charged
Originally posted by PacificMama:
I just got the results back from my daughter's western blot from Igenex. It was postivie for IGG, and equivocal for IGM.I have a consult with Dr. J soon, but can anyone give me a little insight into any details these results might indicate.
thanks.
IGG
18 kda +=*18-kDa p18 flagellin fragment
22 kda -
23-25 kda +/-
28 kda -
30 kda +=30-32-kDa OspA
*30-kDa OspA substrate binding protein31 kda +/-
34 kda +=34-kDa OspB [specific for Bb]
37 kda -
39 kda +=*39-kDa BmpA [specific for Bb]41 kda + + + +=*41-kDa FlaB very possitive
45 kda +=*45-kDa [appeared in IgM in control group in 1998 study done in Poland]
MEDLINE - 9972057 - "...whereas in control group only antibodies
against 45 kDa and 58 kDa were present."
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9972057&form=6&db=m&Dopt=b
[appears for HGE]
MEDLINE - 9620365 - "...confirmed the importance of the 42- to
45-kDa antigens as early, persistent, and specific markers of HGE
infection."
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9620365&form=6&db=m&Dopt=b58 kda +/-
66 kda + +=*66-kDa P66 Oms66 Hsp outer/integral membrane protein
73 kda -
83 kda -
93 kda +/-
IGM18 kda +=*18-kDa p18 flagellin fragment
22 kda -
23-25 kda +/-
28 kda +=*28-kDa OspD, Oms28 [specific for Bb]30 kda +/-
31 kda -
34 kda -
37 kda -
39 kda +=*39-kDa BmpA [specific for Bb]41 kda +/-
45 kda +=same as above
58 kda +/-
66 kda +=*66-kDa P66 Oms66 Hspouter/integral membrane protein
73 kda -
83 kda -
93 kda +=*93-kDa an immunodominant protoplasmic cylinder antigen, associated with the flagellum [specific for Bb]
Explaining Borreliosis (Lyme) Western Blot Tests
Explanation of Western Blot Bands
Igenex Labs on the Western Blot
Melissa Kaplan's Lyme Website Explains Western Blot
Dr. C Explains Western Blot
( No you don't always see a bite and if there's no bullseye the only way your going to be able to tell is (symptoms) and (((Maybe))) WB or lyme dot blot 3 day urine banged with abx's to free your antigens up for the test.
- = Not Present
+ = Low
++ = Medium
+++ = High
+/- = Equivocal = Indeterminate its there but not as intense as low) )
See this ( . )thats the size of the larva stage tick...
Next nymph size... ( * )
Next is adult ( o ) to ( 0 )
Pretty small????? HUH
[This message has been edited by treepatrol (edited 02 March 2005).]